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Stock-Based Compensation (Details Narrative) - USD ($)
12 Months Ended
Feb. 19, 2019
Sep. 28, 2018
Dec. 31, 2020
Dec. 31, 2019
Jun. 15, 2020
Unrecognized compensation cost related to non-vested stock based compensation     $ 1,400,000    
Stock based compensation cost expected to be recognized, weighted average period     1 year 1 month 6 days    
Equity Stock Awards [Member] | Granted Under 2018 Plan and 2007 Plan [Member]          
Number of shares reserved for future issuance     4,484,721    
Inducement Awards [Member]          
Number of shares reserved for future issuance     140,004    
Stock Options and Restricted Stock Awards [Member]          
Compensation cost     $ 1,900,000 $ 2,300,000  
Stock Options and Restricted Stock Awards [Member] | Research and Development Expense [Member]          
Compensation cost     800,000 900,000  
Stock Options and Restricted Stock Awards [Member] | General and Administrative Expense [Member]          
Compensation cost     $ 1,100,000 $ 1,400,000  
2018 Stock Incentive Plan [Member]          
Equity awards, number of stock authorized     2,700,000    
Number of shares reserved for future issuance     6,505,924    
2018 Stock Incentive Plan [Member] | Minimum [Member]          
Number of equity awards available for future issuance     1,200,000   2,500,000
2018 Stock Incentive Plan [Member] | Maximum [Member]          
Number of equity awards available for future issuance     3,900,000   6,400,000
2007 Stock Incentive Plan [Member]          
Stock options, strike price description     Options are generally granted with strike prices equal to the fair market value of a share of Celsion common stock on the date of grant. Incentive stock options may be granted to purchase shares of common stock at a price not less than 100% of the fair market value of the underlying shares on the date of grant, provided that the exercise price of any incentive stock option granted to an eligible employee owning more than 10% of the outstanding stock of Celsion must be at least 110% of such fair market value on the date of grant. Only officers and key employees may receive incentive stock options.    
Inducement Option Grants [Member] | Five New Employees [Member]          
Inducement option grant, exercise price per share $ 2.18 $ 2.77      
Option vested period 3 years 3 years      
Inducement Option Grants [Member] | Five New Employees [Member] | Restricted Stock [Member]          
Number of shares issued 13,000 19,000      
Inducement Option Grants [Member] | Five New Employees [Member] | Common Stock Outstanding [Member]          
Number of shares issued 140,004 164,004      
2018 Plan [Member]          
Number of shares reserved for future issuance     2,018,453    
2019 Bonus Program [Member] | Common Stock Outstanding [Member]          
Number of shares issued     429,855    
Annual bonus awards, percentage     50.00%