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Condensed Consolidated Statements of Changes in Stockholders' Equity (Unaudited) - USD ($)
Common Stock Outstanding [Member]
Additional Paid in Capital [Member]
Treasury Stock [Member]
Accumulated Other Comprehensive Income [Member]
Accumulated Deficit [Member]
Total
Balance at Dec. 31, 2019 $ 232,562 $ 304,885,663 $ (85,188) $ 42,778 $ (290,516,780) $ 14,559,035
Balance, shares at Dec. 31, 2019 23,255,818   334      
Net loss (5,056,878) (5,056,878)
Sale of equity through equity financing facilities net of fees $ 55,713 5,739,034 5,794,747
Sale of equity through equity financing facilities net of fees, shares 5,571,428          
Realized and unrealized gains and losses, net, on investment securities (38,965) (38,965)
Stock-based compensation expense 451,965 451,965
Issuance of restricted stock $ 4,299 494,333 498,632
Issuance of restricted stock, shares 429,855          
Balance at Mar. 31, 2020 $ 292,574 311,570,995 $ (85,188) 3,813 (295,573,658) 16,208,536
Balance, shares at Mar. 31, 2020 29,257,101   334      
Balance at Dec. 31, 2019 $ 232,562 304,885,663 $ (85,188) 42,778 (290,516,780) 14,559,035
Balance, shares at Dec. 31, 2019 23,255,818   334      
Balance at Dec. 31, 2020 $ 407,014 330,289,596 $ (85,188) (312,000,341) 18,611,081
Balance, shares at Dec. 31, 2020 40,701,022   334      
Net loss (5,689,003) (5,689,003)
Sale of equity through equity financing facilities net of fees $ 330,941 38,612,537 38,943,478
Sale of equity through equity financing facilities net of fees, shares 33,094,085          
Shares issued upon exercise of common stock warrants, net of fees $ 12,166 1,496,500 1,508,666
Shares issued upon exercise of common stock warrants, net of fees, shares 1,216,667          
Shares issued upon exercise of options to purchase common stock $ 75 4,650 4,725
Shares issued upon exercise of options to purchase common stock, shares 7,500          
Realized and unrealized gains and losses, net, on investment securities 1,785 1,785
Stock-based compensation expense 1,579,326 1,579,326
Balance at Mar. 31, 2021 $ 750,196 $ 371,982,609 $ (85,188) $ 1,785 $ (317,689,344) $ 54,960,058
Balance, shares at Mar. 31, 2021 75,019,274   334