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Financial Condition and Business Plan (Details Narrative) - USD ($)
1 Months Ended 6 Months Ended 12 Months Ended
Jun. 16, 2021
May 10, 2021
Mar. 19, 2021
Aug. 28, 2020
Jun. 18, 2021
Jan. 31, 2021
Sep. 30, 2020
Jun. 30, 2018
Jun. 30, 2021
Dec. 31, 2019
Dec. 31, 2018
Apr. 05, 2021
Dec. 31, 2020
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                          
Retained Earnings (Accumulated Deficit)                 $ 323,137,741       $ 312,000,341
[custom:CashAndCashEquivalentsRestrictedCashShorttermInvestmentsAndReceivableOnSaleOfNetOperatingLosses-0]                 64,500,000        
[custom:ReceivableOnSaleOfNetOperatingLosses-0]                 $ 1,850,000        
Horizon Credit Agreement [Member] | Horizon Technology Finance Corporation [Member]                          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                          
Proceeds from Contributed Capital               $ 10,000,000          
Debt Instrument, Face Amount       $ 10,000,000                  
Horizon Credit Agreement [Member] | Horizon Technology Finance Corporation [Member] | London Interbank Offered Rate (LIBOR) [Member]                          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                          
Debt Instrument, Interest Rate, Stated Percentage               7.625%          
Amendment to Horizon Credit Agreement [Member] | Horizon Technology Finance Corporation [Member]                          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                          
Repayments of Notes Payable       5,000,000                  
Debt Instrument, Face Amount       5,000,000                  
Debt instrument related end term charges       $ 200,000                  
SVB Loan Facility [Member]                          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                          
Debt Instrument, Interest Rate, Stated Percentage         3.25%                
Line of Credit Facility, Maximum Borrowing Capacity         $ 10,000,000                
Line of Credit Facility, Remaining Borrowing Capacity         $ 4,000,000                
Debt Instrument, Description         Payments under the loan agreement are interest only for the first 24 months after loan closing, followed by a 24-month amortization period of principal and interest through the scheduled maturity date.       Payments under the loan agreement are interest only for the first 24 months after loan closing, followed by a 24-month amortization period of principal and interest through the scheduled maturity date.        
SVB Loan Facility [Member] | Silicon Valley Bank [Member]                          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                          
Line of Credit Facility, Maximum Borrowing Capacity         $ 10,000,000       $ 10,000,000        
Line of Credit Facility, Remaining Borrowing Capacity                 $ 4,000,000        
SVB Loan Facility [Member] | Prime Rate [Member] | Silicon Valley Bank [Member]                          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                          
Debt Instrument, Interest Rate, Stated Percentage                 3.25%        
SVB Loan Facility [Member] | Horizon Technology Finance Corporation [Member]                          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                          
[custom:RepaymentOfOutstandingIndebtednessAmount-0]                 $ 6,000,000        
Capital on DemandTM Sales Agreement [Member] | Jones Trading Institutional Services, LLC [Member]                          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                          
[custom:CashAndCashEquivalentsRestrictedCashShorttermInvestmentsAndReceivableOnSaleOfNetOperatingLosses-0]                 $ 64,500,000        
Proceeds from Contributed Capital     $ 6,900,000                    
Debt Instrument, Face Amount           $ 35,000,000           $ 15,000,000  
Proceeds from Warrant Exercises           $ 1,500,000              
New Jersey [Member]                          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                          
[custom:NetProceedsFromSaleOfNetOperatingLosses] $ 1,600,000           $ 2,000,000.0     $ 12,200,000 $ 13,000,000    
New Jersey [Member] | Minimum [Member]                          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                          
[custom:NetProceedsFromSaleOfNetOperatingLosses]   $ 15,000,000                      
New Jersey [Member] | Maximum [Member]                          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                          
[custom:NetProceedsFromSaleOfNetOperatingLosses] $ 1,400,000 $ 20,000,000