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Condensed Consolidated Statements of Changes in Stockholders' Equity (Unaudited) - USD ($)
Common Stock [Member]
Additional Paid-in Capital [Member]
Treasury Stock [Member]
AOCI Attributable to Parent [Member]
Retained Earnings [Member]
Total
Beginning balance, value at Dec. 31, 2019 $ 232,562 $ 304,885,663 $ (85,188) $ 42,778 $ (290,516,780) $ 14,559,035
Balance, shares at Dec. 31, 2019 23,255,818   334      
Net loss (10,399,813) (10,399,813)
Sale of equity through equity financing facilities $ 94,027 18,088,572 18,182,599
Sale of equity through equity financing facilities net of fees, shares 9,402,843          
Realized and unrealized gains and losses, net, on investments securities (34,912) (34,912)
Issuance of common stock upon exercise of options $ 1,409 370,486 371,895
Issuance of common stock upon exercise of options, shares 140,864          
Common stock issued to settle accrued bonuses $ 4,299 494,333 $ 498,632
?Common stock issued to settle accrued bonuses, shares           429,855
Stock-based compensation expense 1,030,726 $ 1,030,726
Ending balance, value at Jun. 30, 2020 $ 332,297 324,869,780 $ (85,188) 7,866 (300,916,593) 24,208,162
Balance, shares at Jun. 30, 2020 33,229,380   334      
Beginning balance, value at Dec. 31, 2019 $ 232,562 304,885,663 $ (85,188) 42,778 (290,516,780) 14,559,035
Balance, shares at Dec. 31, 2019 23,255,818   334      
Ending balance, value at Dec. 31, 2020 $ 407,014 330,289,596 $ (85,188) (312,000,341) 18,611,081
Balance, shares at Dec. 31, 2020 40,701,022   334      
Beginning balance, value at Mar. 31, 2020 $ 292,574 311,570,995 $ (85,188) 3,813 (295,573,658) 16,208,536
Balance, shares at Mar. 31, 2020 29,257,101   334      
Net loss (5,342,935) (5,342,935)
Sale of equity through equity financing facilities $ 38,314 12,349,538 12,387,852
Sale of equity through equity financing facilities net of fees, shares 3,831,415          
Realized and unrealized gains and losses, net, on investments securities 4,053 4,053
Issuance of common stock upon exercise of options $ 1,409 370,486 371,895
Issuance of common stock upon exercise of options, shares 140,864          
Stock-based compensation expense 578,761 578,761
Ending balance, value at Jun. 30, 2020 $ 332,297 324,869,780 $ (85,188) 7,866 (300,916,593) 24,208,162
Balance, shares at Jun. 30, 2020 33,229,380   334      
Beginning balance, value at Dec. 31, 2020 $ 407,014 330,289,596 $ (85,188) (312,000,341) 18,611,081
Balance, shares at Dec. 31, 2020 40,701,022   334      
Ending balance, value at Mar. 31, 2021 $ 750,196 371,982,609 $ (85,188) 1,785 (317,689,344) 54,960,058
Balance, shares at Mar. 31, 2021 75,019,274   334      
Beginning balance, value at Dec. 31, 2020 $ 407,014 330,289,596 $ (85,188) (312,000,341) 18,611,081
Balance, shares at Dec. 31, 2020 40,701,022   334      
Net loss (11,137,400) (11,137,400)
Sale of equity through equity financing facilities $ 446,326 52,250,939 52,697,265
Sale of equity through equity financing facilities net of fees, shares 44,632,547          
Shares issued upon exercise of common stock warrants, net of fees $ 12,166 1,496,500 1,508,666
Shares issued upon exercise of common stock warrants, net of fees, shares 1,216,667          
Shares issued upon exercise of options to purchase common stock $ 75 4,650 4,725
Shares issued upon exercise of options to purchase common stock, shares 7,500          
Realized and unrealized gains and losses, net, on investments securities (3,770) (3,770)
Stock-based compensation expense 2,372,945 2,372,945
Ending balance, value at Jun. 30, 2021 $ 865,581 386,414,630 $ (85,188) (3,770) (323,137,741) 64,053,512
Balance, shares at Jun. 30, 2021 86,557,736   334      
Beginning balance, value at Mar. 31, 2021 $ 750,196 371,982,609 $ (85,188) 1,785 (317,689,344) 54,960,058
Balance, shares at Mar. 31, 2021 75,019,274   334      
Net loss (5,448,397) (5,448,397)
Sale of equity through equity financing facilities $ 115,385 13,638,402 13,753,787
Sale of equity through equity financing facilities net of fees, shares 11,538,462          
Realized and unrealized gains and losses, net, on investments securities (5,555) (5,555)
Stock-based compensation expense 793,619 793,619
Ending balance, value at Jun. 30, 2021 $ 865,581 $ 386,414,630 $ (85,188) $ (3,770) $ (323,137,741) $ 64,053,512
Balance, shares at Jun. 30, 2021 86,557,736   334