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v3.21.2

Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($) | 3 Months Ended | 9 Months Ended | 12 Months Ended
--- | --- | --- | ---
Sep. 30, 2021 | Sep. 30, 2020 | Sep. 30, 2021 | Sep. 30, 2020 | Dec. 31, 2020
Cash flows from operating activities: |  |  |  |  |
Net loss | $ (5,410,544) | $ (8,071,596) | $ (16,547,944) | $ (18,471,409) |
Adjustments to reconcile net loss to net cash used in operating activities: |  |  |  |  |
Depreciation and amortization |  |  | 542,740 | 572,065 |
Change in fair value of earn-out milestone liability | 257,000 | 1,099,721 | 327,000 | 1,397,291 |
Recognition of deferred revenue |  |  | (375,000) | (375,000) |
Stock-based compensation costs |  |  | 3,073,569 | 1,448,202 |
Deferred income tax asset |  |  | 1,845,823 | 1,819,324 |
Impairment of in-process research and development |  | 2,370,257 |  | 2,370,257 |
Amortization of deferred finance charges and debt discount associated with notes payable |  |  | 191,571 | 439,786 |
Fair value of warrants issued in exchange for services |  |  |  | 44,798 |
Net changes in: |  |  |  |  |
Accrued interest on investment securities |  |  | (38,404) | 21,369 |
Advances, deposits, and other current assets |  |  | (552,567) | (286,991) |
Accounts payable and accrued liabilities |  |  | 397,701 | (866,748) |
Net cash used in operating activities |  |  | (11,135,511) | (11,887,056) |
Cash flows from investing activities: |  |  |  |  |
Purchases of investment securities |  |  | (40,862,225) | (9,956,892) |
Proceeds from sale and maturity of investment securities |  |  | 12,000,000 | 17,900,000 |
Purchases of property and equipment |  |  | (285,971) | (13,918) |
Net cash (used in) provided by investing activities |  |  | (29,148,196) | 7,929,190 |
Cash flows from financing activities: |  |  |  |  |
Proceeds from sale of common stock equity, net of issuance costs |  |  | 52,688,945 | 20,250,426 |
Proceeds from issuance of common stock upon conversion of stock warrants |  |  | 1,508,666 |  |
Proceeds from issuance of common stock upon conversion of stock options |  |  | 4,725 | 371,895 |
Proceeds from the SVB Loan Facility, net of issuance costs |  |  | 5,756,630 |  |
Payoff of the Horizon Credit Agreement and accrued end of term fees |  |  | (5,190,587) | (5,200,000) |
Proceeds from Payroll Protection Program (PPP) loans |  |  |  | 1,324,750 |
Repayments on Payroll Protection Program (PPP) loans |  |  |  | (1,324,750) |
Net cash provided by financing activities |  |  | 54,768,379 | 15,422,321 |
Change in cash, cash equivalents and restricted cash |  |  | 14,484,672 | 11,464,455 |
Cash, cash equivalents and restricted cash at beginning of period |  |  | 17,164,177 | 6,875,273 | $ 6,875,273
Cash, cash equivalents and restricted cash at end of period | $ 31,648,849 | $ 18,339,728 | 31,648,849 | 18,339,728 | $ 17,164,177
Supplemental disclosures of cash flow information: |  |  |  |  |
Interest paid |  |  | (307,985) | (685,913) |
Cash paid for amounts included in measurement of lease liabilities: |  |  |  |  |
Operating cash flows from lease payments |  |  | 418,696 | 393,947 |
Common stock issued to settle accrued bonuses |  |  |  | 498,632 |
Fair value of warrants issued in connection with debt facility, net of cancelled warrants |  |  |  | 81,102 |
Realized and unrealized gains (losses), net, on investment securities |  |  | $ 2,139 | $ (42,778) |

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