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Financial Condition and Business Plan (Details Narrative) - USD ($)
1 Months Ended 9 Months Ended 12 Months Ended
Jun. 16, 2021
Mar. 19, 2021
Aug. 28, 2020
Jun. 18, 2021
Jan. 31, 2021
Sep. 30, 2020
Jun. 30, 2018
Sep. 30, 2021
Sep. 29, 2021
Dec. 31, 2019
Dec. 31, 2018
Apr. 05, 2021
Dec. 31, 2020
Sep. 30, 2018
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                            
Cumulative net losses               $ 328,548,285         $ 312,000,341  
Cash and cash equivalents, restricted cash, short-term investments, interest receivable               60,600,000            
Receivable on sale of net operating losses               $ 1,850,000            
Horizon Credit Agreement [Member] | Horizon Technology Finance Corporation [Member]                            
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                            
Proceeds from Contributed Capital             $ 10,000,000              
Debt Instrument, Face Amount     $ 10,000,000                      
Horizon Credit Agreement [Member] | Horizon Technology Finance Corporation [Member] | London Interbank Offered Rate (LIBOR) [Member]                            
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                            
Debt Instrument, Interest Rate, Stated Percentage                           7.625%
SVB Loan Facility [Member]                            
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                            
Debt Instrument, Description       Payments under the loan agreement are interest only for the first 24 months after loan closing, followed by a 24-month amortization period of principal and interest through the scheduled maturity date.       Payments under the loan agreement are interest only (calculated based on one-month LIBOR plus 7.625%) for the first 24 months through July 2020, followed by a 21-month amortization period of principal and interest starting on August 1, 2020 and ending through the scheduled maturity date            
Debt Instrument, Interest Rate, Stated Percentage       3.25%                    
Line of Credit Facility, Maximum Borrowing Capacity       $ 10,000,000                    
Line of Credit Facility, Remaining Borrowing Capacity       $ 4,000,000                    
SVB Loan Facility [Member] | Silicon Valley Bank [Member]                            
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                            
Line of Credit Facility, Maximum Borrowing Capacity               $ 10,000,000            
Line of Credit Facility, Remaining Borrowing Capacity               $ 4,000,000            
SVB Loan Facility [Member] | Prime Rate [Member] | Silicon Valley Bank [Member]                            
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                            
Debt Instrument, Interest Rate, Stated Percentage               3.25%            
SVB Loan Facility [Member] | Horizon Technology Finance Corporation [Member]                            
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                            
Repayment of outstanding in-debtedness amount               $ 6,000,000            
Amendment to Horizon Credit Agreement [Member] | Horizon Technology Finance Corporation [Member]                            
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                            
Repayments of Notes Payable     5,000,000                      
Debt Instrument, Face Amount     5,000,000                      
Debt instrument related end term charges     $ 200,000                      
Capital on DemandTM Sales Agreement [Member] | Jones Trading Institutional Services, LLC [Member]                            
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                            
Cash and cash equivalents, restricted cash, short-term investments, interest receivable               60,600,000            
Proceeds from Contributed Capital   $ 6,900,000                        
Debt Instrument, Face Amount         $ 35,000,000             $ 15,000,000    
Proceeds from Warrant Exercises         $ 1,500,000                  
New Jersey [Member]                            
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                            
Net proceeds from sale of net operating losses $ 1,600,000         $ 2,000,000.0   $ 20,000,000 $ 15,000,000 $ 12,200,000 $ 13,000,000      
New Jersey [Member] | Maximum [Member]                            
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                            
Net proceeds from sale of net operating losses $ 1,400,000