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LICENSES OF INTELLECTUAL PROPERTY AND PATENTS (Details Narrative) - USD ($) | 12 Months Ended |  |
--- | --- | --- | ---
Dec. 31, 2021 | Dec. 31, 2020 | Jan. 31, 2003
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Common stock, shares, issued | 5,770,538 | 2,713,424 |
Common stock, value, issued | $ 57,705 | $ 27,134 |
License Agreement [Member] | Duke University [Member] |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Number of days before issuance factoring into average closing price | 20 |  |
Common stock, shares, issued |  |  | 253,691
Common stock, value, issued |  |  | $ 2,200,000

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