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FINANCIAL CONDITION (Details Narrative) - USD ($)
 1 Months Ended 12 Months Ended
Jun. 18, 2021
Aug. 28, 2020
Dec. 31, 2021
Dec. 31, 2020
Jun. 30, 2018
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Sep. 30, 2018
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                    
Cumulated net losses     $ 332,769,591 $ 312,000,341   $ 332,769,591 $ 312,000,341      
Cash and cash equivalents, short-term investments     56,900,000     56,900,000        
[custom:ReceivableOnSaleOfNetOperatingLosses-0]     1,400,000 1,900,000   $ 1,400,000 1,900,000      
Horizon Credit Agreement [Member] | Horizon Technology Finance Corporation [Member]                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                    
Proceeds from Contributed Capital         $ 10,000,000          
Debt Instrument, Face Amount   $ 10,000,000                
Horizon Credit Agreement [Member] | Horizon Technology Finance Corporation [Member] | London Interbank Offered Rate (LIBOR) [Member]                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                    
Debt Instrument, Interest Rate, Stated Percentage                   7.625%
SVB Loan Facility [Member]                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                    
Debt Instrument, Description Payments under the loan agreement are interest only for the first 24 months after loan closing, followed by a 24-month amortization period of principal and interest through the scheduled maturity date.         Payments under the loan agreement are interest only (calculated based on one-month LIBOR plus 7.625%) for the first 24 months through July 2020, followed by a 21-month amortization period of principal and interest starting on August 1, 2020 and ending through the scheduled maturity date on April 1, 2023.        
Debt Instrument, Interest Rate, Stated Percentage 3.25%                  
Line of Credit Facility, Maximum Borrowing Capacity $ 10,000,000                  
Line of Credit Facility, Remaining Borrowing Capacity $ 4,000,000                  
SVB Loan Facility [Member] | Silicon Valley Bank [Member]                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                    
Line of Credit Facility, Maximum Borrowing Capacity     10,000,000     $ 10,000,000        
Line of Credit Facility, Remaining Borrowing Capacity     $ 4,000,000     $ 4,000,000        
SVB Loan Facility [Member] | Prime Rate [Member] | Silicon Valley Bank [Member]                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                    
Debt Instrument, Interest Rate, Stated Percentage     3.25%     3.25%        
SVB Loan Facility [Member] | Horizon Technology Finance Corporation [Member]                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                    
Repayment of outstanding in-debtedness amount     $ 6,000,000     $ 6,000,000        
Amendment to Horizon Credit Agreement [Member] | Horizon Technology Finance Corporation [Member]                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                    
Repayments of Notes Payable   5,000,000                
Debt Instrument, Face Amount   5,000,000 5,000,000     5,000,000        
Debt instrument related end term charges   $ 200,000                
New Jersey [Member]                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                    
Net proceeds from sale of net operating losses     $ 1,500,000 $ 2,000,000.0   1,400,000 1,900,000 $ 12,200,000 $ 13,000,000  
Proceeds from Contributed Capital             $ 1,900,000      
New Jersey [Member] | Minimum [Member]                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                    
Net proceeds from sale of net operating losses           15,000,000        
New Jersey [Member] | Maximum [Member]                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                    
Net proceeds from sale of net operating losses           20,000,000        
Operating Costs and Expenses           $ 3,400,000