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STOCKHOLDERS’ EQUITY (Details Narrative) - USD ($)
 1 Months Ended 9 Months Ended 12 Months Ended
Mar. 03, 2022
Feb. 28, 2022
Jan. 10, 2022
Mar. 31, 2021
Mar. 19, 2021
Jan. 22, 2021
Sep. 08, 2020
Jun. 22, 2020
Feb. 27, 2020
Dec. 04, 2018
Sep. 30, 2018
Sep. 30, 2021
Dec. 31, 2021
Dec. 31, 2020
Feb. 28, 2021
Mar. 12, 2020
Feb. 28, 2020
Accumulated Other Comprehensive Income (Loss) [Line Items]                                  
Shelf registration statement amount         $ 100,000,000           $ 75,000,000            
Reverse Stock Split                         On February 28, 2022, the Company effected a 15-for-1 reverse stock split of its common stock which was made effective for trading purposes as of the commencement of trading on March 31, 2022. As of that date, each 15 shares of issued and outstanding common stock and equivalents was consolidated into one share of common stock. All shares have been restated to reflect the effects of the 15-for-1 reverse stock split. In addition, at the market open on March 1, 2022, the Company’s common stock started trading under a new CUSIP number 15117N602 although the Company’s ticker symbol, CLSN, remained unchanged.        
Stockholders equity note changes in capital structure description                         To continue listing on The NASDAQ Capital Market, which requires that the Company comply with the applicable listing requirements under NASDAQ Marketplace Rules, which requirements include, among others, a minimum bid price of at least $1.00 per share. On December 2, 2021, the Company received a letter from NASDAQ indicating that the closing bid price of the Company’s Common Stock fell below $1.00 per share for the previous 30 consecutive business days, and that the Company was therefore not in compliance with the minimum bid price requirement for continued inclusion on The NASDAQ Capital Market. The Company had 180 calendar days, until May 31, 2022, to regain compliance with this requirement, which occurs when the closing bid price of the Company’s Common Stock is at least $1.00 per share for a minimum of ten consecutive business days during the 180-day compliance period.        
Reverse stock split common stock outstanding                         5,770,516        
Common stock, shares outstanding                         5,770,516 2,713,402      
Warrants                         7,273       213,333
Proceeds from Issuance of Common Stock                         $ 52,688,946 $ 22,811,669      
Class of Warrant or Right, Exercise Price of Warrants or Rights                         $ 48.30        
Preferred Stock, Shares Issued                         0 0      
Preferred Stock, Par or Stated Value Per Share                         $ 0.01 $ 0.01      
Common Stock, Par or Stated Value Per Share                         $ 0.01 $ 0.01      
Preferred Stock Value                              
Preferred Stock Shares Outstanding                         0 0      
Subsequent Event [Member]                                  
Accumulated Other Comprehensive Income (Loss) [Line Items]                                  
Reverse Stock Split   On February 28, 2022, the Company effected a 15-for-1 reverse stock split of its common stock which was made effective for trading purposes as of the commencement of trading on March 1, 2022.                              
Common stock, shares outstanding   15                              
Share Price     $ 285                            
Preferred Stock, Par or Stated Value Per Share     $ 300                            
Proceeds from Issuance of Preferred Stock and Preference Stock     $ 14,250,000                            
Preferred Stock Value $ 300                                
Proceeds From Issuance Under Placement $ 1,000,000                                
Subsequent Event [Member] | Series A Convertible Redeemable Preferred Stock [Member]                                  
Accumulated Other Comprehensive Income (Loss) [Line Items]                                  
Share Price     $ 300                            
Preferred Stock, Shares Issued     50,000                            
Preferred Stock, Par or Stated Value Per Share     $ 0.01                            
Preferred Stock, Convertible, Conversion Price     $ 13.65                            
Convertible Preferred Stock, Shares Issued upon Conversion     1,098,901                            
Common Stock, Par or Stated Value Per Share     $ 13.65                            
Preferred Stock Shares Outstanding 50,000                                
Subsequent Event [Member] | Series B Convertible Redeemable Preferred Stock [Member]                                  
Accumulated Other Comprehensive Income (Loss) [Line Items]                                  
Share Price     $ 300                            
Preferred Stock, Shares Issued     50,000                            
Preferred Stock, Par or Stated Value Per Share     $ 0.01                            
Preferred Stock, Convertible, Conversion Price     $ 15.00                            
Convertible Preferred Stock, Shares Issued upon Conversion     1,000,000                            
Preferred Stock Voting Rights     right to cast 3,000 votes per share                            
Common Stock, Par or Stated Value Per Share     $ 15.00                            
Preferred Stock Shares Outstanding 50,000                                
Capital on DemandTM Sales Agreement [Member]                                  
Accumulated Other Comprehensive Income (Loss) [Line Items]                                  
Less than 12 months, unrealized gains, fair value                   $ 16,000,000.0              
Capital on Demand Agreement [Member]                                  
Accumulated Other Comprehensive Income (Loss) [Line Items]                                  
Stock Issued During Period, Shares, New Issues                         500,000 300,000      
Proceeds from Issuance of Common Stock                         $ 6,900,000 $ 6,200,000      
Securities Purchase Agreement [Member]                                  
Accumulated Other Comprehensive Income (Loss) [Line Items]                                  
Stock Issued During Period, Shares, New Issues                 304,761                
Proceeds from Issuance of Common Stock                 $ 4,800,000                
Shares Issued, Price Per Share                 $ 15.75                
Securities Purchase Agreement [Member] | January 2021 Registered Direct Offering [Member]                                  
Accumulated Other Comprehensive Income (Loss) [Line Items]                                  
Stock Issued During Period, Shares, New Issues           1,728,395                      
Proceeds from Issuance of Common Stock           $ 35,000,000                      
Share Price           $ 20.25                      
Placement agent fee description.           In connection with the January 2021 Offering, the Company entered into a placement agent agreement with A.G.P./Alliance Global Partners (“AGP,” and together with Brookline Capital Markets, the “January 2021 Placement Agents”) pursuant to which the Company agreed to pay the January 2021 Placement Agents a cash fee equal to 7% of the aggregate gross proceeds raised from the sale of the securities sold in the January 2021 Offering and reimburse the January 2021 Placement Agents for certain of their expenses in an amount not to exceed $82,500.                      
Securities Purchase Agreement [Member] | March 2021 Registered Direct Offering [Member]                                  
Accumulated Other Comprehensive Income (Loss) [Line Items]                                  
Stock Issued During Period, Shares, New Issues       769,230                          
Proceeds from Issuance of Common Stock       $ 15,000,000                          
Share Price       $ 19.50                          
Placement agent fee description.       Placement Agent Agreement”) with AGP, as lead placement agent (together with JonesTrading Institutional Services LLC and Brookline Capital Markets, a division of Arcadia Securities, LLC, serving as co-placement agents, the “March 2021 Placement Agents”), pursuant to which the Company agreed to pay the March 2021 Placement Agents an aggregate cash fee equal to 7% of the aggregate gross proceeds raised from the sale of the securities sold in the offering and reimburse the Placement Agents for certain of their expenses in an amount not to exceed $82,500.                          
Exchange Agreements [Member]                                  
Accumulated Other Comprehensive Income (Loss) [Line Items]                                  
Class of Warrant or Right, Number of Securities Called by Each Warrant or Right                       81,111          
Proceeds from Issuance of Warrants                       $ 1,500,000          
Underwriting Agreement [Member] | Underwritten Offering [Member]                                  
Accumulated Other Comprehensive Income (Loss) [Line Items]                                  
Stock Issued During Period, Shares, New Issues               177,777                  
Proceeds from Issuance of Common Stock               $ 9,100,000                  
Shares Issued, Price Per Share               $ 56.25                  
Share Price               52.3125                  
Underwriting discount price per share               $ 3.9375                  
Payments from sale of nols               7.00%                  
LPC Purchase Agreement [Member] | Lincoln Park Capital Fund, LLC [Member]                                  
Accumulated Other Comprehensive Income (Loss) [Line Items]                                  
Stock Issued During Period, Shares, New Issues             26,000,000.0                    
Proceeds from Issuance of Common Stock                           $ 2,200,000      
Maximum [Member]                                  
Accumulated Other Comprehensive Income (Loss) [Line Items]                                  
Common stock, shares outstanding                         6,600,000        
Warrants                         2,500,000        
Maximum [Member] | Subsequent Event [Member]                                  
Accumulated Other Comprehensive Income (Loss) [Line Items]                                  
Proceeds From Issuance Under Placement $ 110,000                                
Minimum [Member]                                  
Accumulated Other Comprehensive Income (Loss) [Line Items]                                  
Common stock, shares outstanding                         400,000        
Warrants                         200,000   81,111    
Common Stock [Member]                                  
Accumulated Other Comprehensive Income (Loss) [Line Items]                                  
Reverse stock split common stock outstanding                         86,557,736        
Stock Issued During Period, Shares, New Issues                         2,975,503 1,111,615      
Original Warrants [Member] | Securities Purchase Agreement [Member]                                  
Accumulated Other Comprehensive Income (Loss) [Line Items]                                  
Class of Warrant or Right, Number of Securities Called by Each Warrant or Right                 198,095                
Class of Warrant or Right, Exercise Price of Warrants or Rights                 $ 17.25                
Warrant [Member] | Exchange Agreements [Member]                                  
Accumulated Other Comprehensive Income (Loss) [Line Items]                                  
Class of Warrant or Right, Number of Securities Called by Each Warrant or Right                               213,333  
Class of Warrant or Right, Exercise Price of Warrants or Rights                               $ 18.60  
LPC Commitment Shares [Member] | LPC Purchase Agreement [Member] | Lincoln Park Capital Fund, LLC [Member]                                  
Accumulated Other Comprehensive Income (Loss) [Line Items]                                  
Stock Issued During Period, Shares, New Issues             218,854