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STOCK-BASED COMPENSATION (Details Narrative) - USD ($)
$ / shares in Units, $ in Millions
12 Months Ended
Feb. 19, 2019
Sep. 28, 2018
Dec. 31, 2021
Dec. 31, 2020
Jun. 10, 2021
Jun. 15, 2020
May 14, 2019
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]              
Common Stock, Shares Issued     5,770,538 2,713,424      
Unrecognized compensation cost     $ 1.7        
Cost recognized over a weighted-average period     1 year        
Equity Stock Awards [Member] | Granted Under 2018 Plan and 2007 Plan [Member]              
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]              
Common Stock, Capital Shares Reserved for Future Issuance     433,676        
Inducement Awards [Member]              
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]              
Common Stock, Capital Shares Reserved for Future Issuance     9,332        
Stock Options and Restricted Stock Awards [Member]              
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]              
Compensation cost     $ 3.8 $ 1.9      
Stock Options and Restricted Stock Awards [Member] | Research and Development Expense [Member]              
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]              
Compensation cost     1.4 0.8      
Stock Options and Restricted Stock Awards [Member] | General and Administrative Expense [Member]              
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]              
Compensation cost     $ 2.4 $ 1.1      
Common Stock, Shares Issued       429,855      
2018 Stock Incentive Plan [Member]              
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]              
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Authorized     180,000        
Common Stock, Capital Shares Reserved for Future Issuance     946,561        
2018 Stock Incentive Plan [Member] | Minimum [Member]              
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]              
Shares Available for Grant         513,333 166,667 80,000
2018 Stock Incentive Plan [Member] | Maximum [Member]              
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]              
Shares Available for Grant         940,000 426,667 260,000
2007 Stock Incentive Plan [Member]              
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]              
Stock options, strike price description     Options are generally granted with strike prices equal to the fair market value of a share of Celsion common stock on the date of grant. Incentive stock options may be granted to purchase shares of common stock at a price not less than 100% of the fair market value of the underlying shares on the date of grant, provided that the exercise price of any incentive stock option granted to an eligible employee owning more than 10% of the outstanding stock of Celsion must be at least 110% of such fair market value on the date of grant. Only officers and key employees may receive incentive stock options.        
Inducement Option Grants [Member] | Five New Employees [Member]              
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]              
Exercise price per share $ 32.70 $ 41.55          
Award Vesting Period 3 years            
Inducement Option Grants [Member] | Five New Employees [Member] | Restricted Stock [Member]              
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]              
Shares, Issued 8,666 1,266          
Inducement Option Grants [Member] | Five New Employees [Member] | Common Stock [Member]              
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]              
Shares, Issued 9,332 10,933          
2018 Plan [Member]              
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]              
Common Stock, Capital Shares Reserved for Future Issuance     512,884