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Statements of Changes in Stockholders' Equity (Unaudited) - USD ($)
Common Stock [Member]
Additional Paid-in Capital [Member]
Treasury Stock [Member]
AOCI Attributable to Parent [Member]
Retained Earnings [Member]
Total
Beginning Balance at Dec. 31, 2020 $ 27,134 $ 330,669,476 $ (85,188) $ (312,000,341) $ 18,611,081
Beginning Balance, shares at Dec. 31, 2020 2,713,402   22      
Net loss (5,689,003) (5,689,003)
Realized and unrealized gains and losses, net, on investments securities 1,785 1,785
Stock-based compensation expense 1,579,326 1,579,326
Sale of equity through equity financing facilities $ 22,063 38,921,415 38,943,478
Sale of equity through equity financing facilities, shares 2,206,272          
Shares issued upon exercise of common stock warrants, net of fees $ 811 1,507,855 1,508,666
Shares issued upon exercise of common stock warrants, net of fees 81,111          
Shares issued upon exercise of options to purchase common stock $ 5 4,720 4,725
Shares issued upon exercise of options to purchase common stock, shares 500          
Ending Balance at Mar. 31, 2021 $ 50,013 372,682,792 $ (85,188) 1,785 (317,689,344) 54,960,058
Ending Balance, shares at Mar. 31, 2021 5,001,285   22      
Beginning Balance at Dec. 31, 2020 $ 27,134 330,669,476 $ (85,188) (312,000,341) 18,611,081
Beginning Balance, shares at Dec. 31, 2020 2,713,402   22      
Ending Balance at Dec. 31, 2021 $ 57,705 388,600,979 $ (85,188) (7,974) (332,769,591) 55,795,931
Ending Balance, shares at Dec. 31, 2021 5,770,516   22      
Net loss (10,474,332) (10,474,332)
Net effect of reverse stock split (49)          
Realized and unrealized gains and losses, net, on investments securities (51,004) (51,004)
Stock-based compensation expense 994,614 994,614
Ending Balance at Mar. 31, 2022 $ 57,505 $ 389,595,593 $ (85,188) $ (58,978) $ (343,243,923) $ 46,265,209
Ending Balance, shares at Mar. 31, 2022 5,770,467   22