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v3.23.1

Consolidated Statements of Cash Flows - USD ($) | 12 Months Ended
--- | ---
Dec. 31, 2022 | Dec. 31, 2021
Cash flows from operating activities: |  |
Net loss | $ (35,898,234) | $ (20,769,250)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation and amortization | 731,629 | 702,918
Change in fair value of earn-out milestone liability | (5,396,000) | (1,622,000)
Stock-based compensation | 2,673,034 | 3,759,737
Change in deferred income tax asset |  | 462,377
Impairment of goodwill and in-process research and development | 13,366,234 | 1,976,101
Amortization of deferred finance charges and debt discount associated with note payable | 181,259 | 237,258
Net changes in: |  |
Accrued interest receivable on investment securities | (20,088) | (108,844)
Advances and deposits on clinical programs and other current assets | (514,600) | (786,718)
Other assets | 133,489 | (124,728)
Accounts payable – trade | 1,039,372 | 302,404
Other accrued liabilities | 1,072,529 | 247,142
Deferred revenue | (500,000) | (500,000)
Net cash used in operating activities | (23,131,376) | (16,223,603)
Cash flows from investing activities: |  |
Purchases of investment in debt securities | (48,191,922) | (53,811,069)
Proceeds from sale and maturity of investment in debt securities | 56,775,000 | 24,000,000
Purchases of property and equipment | (267,800) | (311,613)
Net cash used in investing activities | 8,315,278 | (30,122,682)
Cash flows from financing activities: |  |
Proceeds from redeemable convertible preferred stock offering | 28,500,000 |
Payment upon redemption of redeemable convertible preferred stock | (28,500,000) |
Proceeds from issuance of common stock equity, net of issuance costs | 6,722,667 | 52,688,946
Proceeds from issuance of common stock upon exercise of warrants |  | 1,508,666
Proceeds from issuance of common stock upon exercise of stock options |  | 4,725
Proceeds from notes payable |  | 5,756,630
Payments on notes payable including end-of-term fees |  | (5,190,587)
Net cash provided by financing activities | 6,722,667 | 54,768,380
Change in cash, cash equivalents and restricted cash | (8,093,431) | 8,422,095
Cash, cash equivalents and restricted cash at beginning of year | 25,586,272 | 17,164,177
Cash, cash equivalents and restricted cash at end of year | 17,492,841 | 25,586,272
Supplemental disclosure of cash flow information: |  |
Interest | (4,847,359) | (357,277)
Cash paid for amounts included in measurement of lease liabilities: |  |
Operating cash flows from lease payments | 601,495 | 568,269
Realized and unrealized gains, net, on investment in debt securities | $ 26,494 | $ 7,974

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