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Consolidated Statements of Changes in Stockholders' Equity - USD ($)
Preferred Stock [Member]
Series A and B Preferred Stock [Member]
Common Stock [Member]
Additional Paid-in Capital [Member]
Treasury Stock [Member]
AOCI Attributable to Parent [Member]
Retained Earnings [Member]
Total
Beginning balance, value at Dec. 31, 2020   $ 27,134 $ 330,669,476 $ (85,188) $ (312,000,341) $ 18,611,081
Beginning balance, shares at Dec. 31, 2020   2,713,402   22      
Net loss   (20,769,250) (20,769,250)
Sale of equity through equity financing facilities   $ 29,755 52,659,191 52,688,946
Sale of equity through equity financing facilities, shares   2,975,503          
Realized and unrealized gains and losses, net, on investment securities   (7,974) (7,974)
Stock-based compensation expense   3,759,737 3,759,737
Issuance of common stock upon exercise of options   $ 5 4,720 4,725
Issuance of common stock upon exercise of options, shares   500          
Shares issued pursuant to warrant exercises   $ 811 1,507,855 1,508,666
Shares issued pursuant to warrant exercises, shares   81,111          
Ending balance, value at Dec. 31, 2021 $ 57,705 388,600,979 $ (85,188) (7,974) (332,769,591) 55,795,931
Ending balance, shares at Dec. 31, 2021 5,770,516   22      
Net loss (35,898,234) (35,898,234)
Effect of reverse stock split
Effect of reverse stock split, shares   (27)          
Issuance of preferred stock upon financing $ 28,500,000
Issuance of preferred stock upon financing, shares 100,000            
Redemption of preferred stock $ (28,500,000)
Redemption of preferred stock, shares (100,000)            
Sale of equity through equity financing facilities $ 16,644 6,706,010 6,722,654
Sale of equity through equity financing facilities, shares   1,664,349          
Issuance of common stock for restricted options $ 13 13
Issuance of common stock for restricted options, shares   1,381          
Realized and unrealized gains and losses, net, on investment securities 34,468 34,468
Stock-based compensation expense 2,673,034 2,673,034
Ending balance, value at Dec. 31, 2022 $ 74,362 $ 397,980,023 $ (85,188) $ 26,494 $ (368,667,825) $ 29,327,866
Ending balance, shares at Dec. 31, 2022 7,436,219   22