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Stock-Based Compensation (Details Narrative) - USD ($)
$ / shares in Units, $ in Millions
3 Months Ended
Mar. 17, 2023
Dec. 13, 2022
Sep. 27, 2022
Jul. 19, 2022
Mar. 31, 2023
Mar. 31, 2022
Dec. 31, 2022
Jun. 10, 2021
Jun. 15, 2020
May 14, 2019
May 15, 2018
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                      
Options granted, weighted average exercise price         $ 1.32 $ 4.16          
Common stock, outstanding         9,097,005   7,436,197        
Unrecognized share based compensation         $ 0.8            
Inducement Awards [Member]                      
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                      
Common stock, outstanding         209,751            
Equity Stock Awards [Member] | Granted Under 2018 Plan and 2007 Plan [Member]                      
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                      
Common stock, reserved for future issuance         844,697            
Stock Options and Restricted Stock Awards [Member]                      
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                      
Share based compensation         $ 0.3 $ 1.0          
Stock Options and Restricted Stock Awards [Member] | Research and Development Expense [Member]                      
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                      
Share based compensation         0.1 0.4          
Stock Options and Restricted Stock Awards [Member] | General and Administrative Expense [Member]                      
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                      
Share based compensation         $ 0.2 $ 0.6          
Common Stock [Member]                      
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                      
Shares issued, shares         1,660,608            
Minimum [Member]                      
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                      
Common stock, outstanding         400,000            
Unrecognized share based compensation, period         3 years            
Maximum [Member]                      
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                      
Common stock, outstanding         6,600,000            
Unrecognized share based compensation, period         4 years            
2018 Stock Incentive Plan [Member]                      
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                      
Share-based payment award, shares authorized                     180,000
Shares available for issuance         100,376            
Common stock, reserved for future issuance         945,073            
2018 Stock Incentive Plan [Member] | Minimum [Member]                      
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                      
Shares available for issuance               513,333 166,667 80,000  
2018 Stock Incentive Plan [Member] | Maximum [Member]                      
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                      
Shares available for issuance               940,000 426,667 260,000  
2007 Stock Incentive Plan [Member]                      
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                      
Stock options, strike price description         Options are generally granted with strike prices equal to the fair market value of a share of common stock on the date of grant. Incentive stock options may be granted to purchase shares of common stock at a price not less than 100% of the fair market value of the underlying shares on the date of grant, provided that the exercise price of any incentive stock option granted to an eligible employee owning more than 10% of the outstanding stock of the Company must be at least 110% of such fair market value on the date of grant. Only officers and key employees may receive incentive stock options.            
Inducement Option Grants [Member] | Ten New Employees [Member]                      
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                      
Options granted, weighted average exercise price $ 1.32 $ 1.40 $ 1.65 $ 1.95              
Inducement Option Grants [Member] | Ten New Employees [Member] | Restricted Stock [Member]                      
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                      
Shares issued, shares 1,100 4,000 2,250 63,000              
Inducement Option Grants [Member] | Ten New Employees [Member] | Common Stock [Member]                      
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                      
Shares issued, shares 5,230 19,000 8,501 177,000