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SEGMENT PERFORMANCE MEASURES AND EXPENSES | 12 Months Ended
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Dec. 31, 2024
Segment Reporting [Abstract] |
SEGMENT PERFORMANCE MEASURES AND EXPENSES | 3. SEGMENT PERFORMANCE MEASURES AND EXPENSES The Company operates in one segment for the research and development of our product candidates. The Company’s chief operating decision maker (“CODM”) has been identified as the Chief Executive Officer and President, who reviews operating results to make decisions about allocating resources and assessing performance for the entire Company based on consolidated financial information. Consequently, we view the entire organization as one reportable segment and the strategic purpose of all operating activities (including general & administrative expenses) is to support that one segment. As a pre-revenue research and development company, the CODM evaluates company-wide performance and allocates resources based on non-financial research and development milestones achieved, and to a lesser extent, financial measures of performance such as clinical development (research and development expenses) and general and administrative expenses incurred. Our CODM does not generally evaluate our performance using asset or historical cash flow information. The table below provides a summary of the significant expense categories and consolidated net loss details provided to the CODM (in thousands): SCHEDULE OF SIGNIFICANT EXPENSE CATEGORIES AND CONSOLIDATED NET LOSS
|  | For the year ended December 31, |
|  | (In thousands) |  |  | Change Increase (Decrease) |
|  | 2024 |  |  | 2023 |  |  |  |  |  |  |
Operating Expenses: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Clinical Research |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
OVATION |  | $ | 1,386 |  |  | $ | 1,197 |  |  | $ | 189 |  |  |  | 15.8 | %
Vaccine |  |  | 1,420 |  |  |  | - |  |  |  | 1,420 |  |  |  | 100.0 | %
Other clinical and regulatory |  |  | 2,434 |  |  |  | 1,793 |  |  |  | 641 |  |  |  | 35.8 | %
Subtotal |  |  | 5,240 |  |  |  | 2,990 |  |  |  | 2,250 |  |  |  | 75.3 | %
Non-Clinical R&D and CMC |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
OVATION |  |  | 1,819 |  |  |  | 1,504 |  |  |  | 315 |  |  |  | 20.9 | %
PlaCCine Vaccine |  |  | 2,554 |  |  |  | 4,511 |  |  |  | (1,957 | ) |  |  | (43.4 | )%
Manufacturing (CMC) |  |  | 2,026 |  |  |  | 2,283 |  |  |  | (257 | ) |  |  | (11.3 | )%
Subtotal |  |  | 6,399 |  |  |  | 8,298 |  |  |  | (1,899 | ) |  |  | (22.9 | )%
Research and development expenses |  |  | 11,639 |  |  |  | 11,288 |  |  |  | 351 |  |  |  | 3.1 | %
General and administrative expenses |  |  | 7,493 |  |  |  | 9,742 |  |  |  | (2,249 | ) |  |  | (23.1 | )%
Total operating expenses |  |  | 19,132 |  |  |  | 21,030 |  |  |  | (1,898 | ) |  |  | (9.0 | )%
Loss from operations |  | $ | (19,132 | ) |  | $ | (21,030 | ) |  | $ | (1,898 | ) |  |  | (9.0 | )%

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- Definition The entire disclosure for reporting segments including data and tables. Reportable segments include those that meet any of the following quantitative thresholds a) it's reported revenue, including sales to external customers and intersegment sales or transfers is 10 percent or more of the combined revenue, internal and external, of all operating segments b) the absolute amount of its reported profit or loss is 10 percent or more of the greater, in absolute amount of 1) the combined reported profit of all operating segments that did not report a loss or 2) the combined reported loss of all operating segments that did report a loss c) its assets are 10 percent or more of the combined assets of all operating segments. + References Reference 1: http://www.xbrl.org/2003/role/exampleRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 55 -Paragraph 48 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482785/280-10-55-48 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Topic 280 -SubTopic 10 -Name Accounting Standards 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