<SEC-DOCUMENT>0001213900-19-006662-index.html : 20190418
<SEC-HEADER>0001213900-19-006662.hdr.sgml : 20190418
<ACCEPTANCE-DATETIME>20190418151628
ACCESSION NUMBER:		0001213900-19-006662
CONFORMED SUBMISSION TYPE:	POS AM
PUBLIC DOCUMENT COUNT:		19
FILED AS OF DATE:		20190418
DATE AS OF CHANGE:		20190418

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Aptorum Group Ltd
		CENTRAL INDEX KEY:			0001734005
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			E9
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		POS AM
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-227198
		FILM NUMBER:		19755705

	BUSINESS ADDRESS:	
		STREET 1:		17/F, GUANGDONG INVESTMENT TOWER
		STREET 2:		148 CONNAUGHT ROAD CENTRAL
		CITY:			HONG KONG
		STATE:			F4
		ZIP:			999077
		BUSINESS PHONE:		852 2117 6611

	MAIL ADDRESS:	
		STREET 1:		17/F, GUANGDONG INVESTMENT TOWER
		STREET 2:		148 CONNAUGHT ROAD CENTRAL
		CITY:			HONG KONG
		STATE:			F4
		ZIP:			999077
</SEC-HEADER>
<DOCUMENT>
<TYPE>POS AM
<SEQUENCE>1
<FILENAME>posam2019a1_aptorumgroup.htm
<DESCRIPTION>POST-EFFECTIVE AMENDMENT NO. 1 TO FORM F-1
<TEXT>
Document 1 - file: posam2019a1_aptorumgroup.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>2
<FILENAME>posam2019a1ex5-1_aptorum.htm
<DESCRIPTION>OPINION OF CAYMAN ISLANDS COUNSEL OF APTORUM GROUP LIMITED, AS TO THE VALIDITY OF THE ORDINARY SHARES AND TAX MATTERS
<TEXT>
Document 2 - file: posam2019a1ex5-1_aptorum.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.2
<SEQUENCE>3
<FILENAME>posam2019a1ex5-2_aptorum.htm
<DESCRIPTION>OPINION OF U.S. COUNSEL OF APTORUM GROUP LIMITED, AS TO THE BINDING OBLIGATION OF THE UNDERWRITER WARRANTS UNDER THE LAWS OF THE STATE OF NEW YORK
<TEXT>
Document 3 - file: posam2019a1ex5-2_aptorum.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.1
<SEQUENCE>4
<FILENAME>posam2019a1ex23-1_aptorum.htm
<DESCRIPTION>CONSENT OF MARCUM BERNSTEIN & PINCHUK LLP
<TEXT>
Document 4 - file: posam2019a1ex23-1_aptorum.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>5
<FILENAME>img_001.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 5 - file: img_001.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>6
<FILENAME>img_002.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 6 - file: img_002.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>7
<FILENAME>img_003.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 7 - file: img_003.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>8
<FILENAME>img_004.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 8 - file: img_004.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>9
<FILENAME>img_005.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 9 - file: img_005.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>10
<FILENAME>img_006.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 10 - file: img_006.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>11
<FILENAME>img_007.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 11 - file: img_007.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>12
<FILENAME>img_008.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 12 - file: img_008.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>13
<FILENAME>img_009.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 13 - file: img_009.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>14
<FILENAME>img_010.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 14 - file: img_010.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>15
<FILENAME>img_011.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 15 - file: img_011.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>16
<FILENAME>ex5-2_001.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 16 - file: ex5-2_001.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>17
<FILENAME>img_012.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 17 - file: img_012.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>18
<FILENAME>ex23-1_001.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 18 - file: ex23-1_001.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>19
<FILENAME>ex23-1_002.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 19 - file: ex23-1_002.jpg

</DOCUMENT>
</SEC-DOCUMENT>