    <SEC-DOCUMENT>0001213900-20-029638-index.html : 20201001
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    <ACCEPTANCE-DATETIME>20201001172750
    ACCESSION NUMBER:		0001213900-20-029638
    CONFORMED SUBMISSION TYPE:	424B4
    PUBLIC DOCUMENT COUNT:		12
    FILED AS OF DATE:		20201001
    DATE AS OF CHANGE:		20201001

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Aptorum Group Ltd
    		CENTRAL INDEX KEY:			0001734005
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		IRS NUMBER:				000000000
    		STATE OF INCORPORATION:			E9
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		424B4
    		SEC ACT:		1933 Act
    		SEC FILE NUMBER:	333-248743
    		FILM NUMBER:		201217226

    	BUSINESS ADDRESS:
    		STREET 1:		17 HANOVER SQUARE
    		CITY:			LONDON
    		STATE:			X0
    		ZIP:			W1S 1BN
    		BUSINESS PHONE:		852 3953 7700

    	MAIL ADDRESS:
    		STREET 1:		17 HANOVER SQUARE
    		CITY:			LONDON
    		STATE:			X0
    		ZIP:			W1S 1BN
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>424B4
    <SEQUENCE>1
    <FILENAME>ea127698-424b4_aptorumgroup.htm
    <DESCRIPTION>PROSPECTUS
    <TEXT>
    Document 1 - file: ea127698-424b4_aptorumgroup.htm

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    <SEQUENCE>2
    <FILENAME>image_002.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 2 - file: image_002.jpg

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    <SEQUENCE>3
    <FILENAME>image_003.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 3 - file: image_003.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>image_004.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 4 - file: image_004.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>5
    <FILENAME>image_005.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 5 - file: image_005.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>6
    <FILENAME>image_006.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 6 - file: image_006.jpg

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    <TYPE>GRAPHIC
    <SEQUENCE>7
    <FILENAME>image_007.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 7 - file: image_007.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>8
    <FILENAME>image_008.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 8 - file: image_008.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>9
    <FILENAME>image_009.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 9 - file: image_009.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>10
    <FILENAME>image_010.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 10 - file: image_010.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>11
    <FILENAME>image_011.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 11 - file: image_011.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>12
    <FILENAME>image_012.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 12 - file: image_012.jpg

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