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</LabelSeparator><CurrencyCode>USD</CurrencyCode><FootnoteIndexer /><hasSegments>true</hasSegments><hasScenarios>false</hasScenarios><MCU><KeyName /><CurrencySymbol>$</CurrencySymbol><contextRef><ContextID>From2013-05-09to2013-05-10_custom_SancilioMember_us-gaap_WarrantMember</ContextID><EntitySchema>http://www.sec.gov/CIK</EntitySchema><EntityValue>0000025743</EntityValue><PeriodDisplayName /><PeriodType>duration</PeriodType><PeriodStartDate>2013-05-09T00:00:00</PeriodStartDate><PeriodEndDate>2013-05-10T00:00:00</PeriodEndDate><Segments><anyType xsi:type="Segment"><IsDefaultForEntity>false</IsDefaultForEntity><Name /><IsFromEntityGroup>false</IsFromEntityGroup><ValueName>Warrants</ValueName><ValueType>us-gaap_ClassOfWarrantOrRightAxis</ValueType><Namespace>xbrldi</Namespace><Schema>http://xbrl.org/2006/xbrldi</Schema><DimensionInfo><Id>us-gaap_WarrantMember</Id><dimensionId>us-gaap_ClassOfWarrantOrRightAxis</dimensionId><type>explicitMember</type></DimensionInfo></anyType><anyType xsi:type="Segment"><IsDefaultForEntity>false</IsDefaultForEntity><Name /><IsFromEntityGroup>false</IsFromEntityGroup><ValueName>Sancilio &amp; Company</ValueName><ValueType>us-gaap_CounterpartyNameAxis</ValueType><Namespace>xbrldi</Namespace><Schema>http://xbrl.org/2006/xbrldi</Schema><DimensionInfo><Id>txmd_SancilioMember</Id><dimensionId>us-gaap_CounterpartyNameAxis</dimensionId><type>explicitMember</type></DimensionInfo></anyType></Segments><Scenarios /></contextRef><UPS><UnitProperty><UnitID>Shares</UnitID><UnitType>Standard</UnitType><StandardMeasure><MeasureSchema>http://www.xbrl.org/2003/instance</MeasureSchema><MeasureValue>shares</MeasureValue><MeasureNamespace>xbrli</MeasureNamespace><MeasureDescription /><MeasureType /></StandardMeasure><Scale>0</Scale></UnitProperty><UnitProperty><UnitID>Pure</UnitID><UnitType>Standard</UnitType><StandardMeasure><MeasureSchema>http://www.xbrl.org/2003/instance</MeasureSchema><MeasureValue>pure</MeasureValue><MeasureNamespace>xbrli</MeasureNamespace><MeasureDescription /><MeasureType /></StandardMeasure><Scale>0</Scale></UnitProperty><UnitProperty><UnitID>USD</UnitID><UnitType>Standard</UnitType><StandardMeasure><MeasureSchema>http://www.xbrl.org/2003/iso4217</MeasureSchema><MeasureValue>USD</MeasureValue><MeasureNamespace>iso4217</MeasureNamespace><MeasureDescription /><MeasureType /></StandardMeasure><Scale>0</Scale></UnitProperty></UPS><CurrencyCode>USD</CurrencyCode><OriginalCurrencyCode>USD</OriginalCurrencyCode></MCU><CurrencySymbol>$</CurrencySymbol><Labels><Label Key="CalendarSupplement" Id="0" Label="0 Months Ended" /><Label Key="Calendar" Id="1" Label="May 10, 2013" /><Label Key="us-gaap_ClassOfWarrantOrRightAxis:us-gaap_WarrantMember" Id="2" Label="Warrants" /><Label Key="us-gaap_CounterpartyNameAxis:txmd_SancilioMember" Id="3" Label="Sancilio &amp; Company" /></Labels></Column><Column FlagID="0"><Id>15</Id><IsAbstractGroupTitle>false</IsAbstractGroupTitle><LabelSeparator>

</LabelSeparator><CurrencyCode /><FootnoteIndexer /><hasSegments>true</hasSegments><hasScenarios>false</hasScenarios><MCU><KeyName /><CurrencySymbol /><contextRef><ContextID>From2013-05-01to2013-05-31_custom_SancilioMember_us-gaap_WarrantMember</ContextID><EntitySchema>http://www.sec.gov/CIK</EntitySchema><EntityValue>0000025743</EntityValue><PeriodDisplayName /><PeriodType>duration</PeriodType><PeriodStartDate>2013-05-01T00:00:00</PeriodStartDate><PeriodEndDate>2013-05-31T00:00:00</PeriodEndDate><Segments><anyType xsi:type="Segment"><IsDefaultForEntity>false</IsDefaultForEntity><Name /><IsFromEntityGroup>false</IsFromEntityGroup><ValueName>Warrants</ValueName><ValueType>us-gaap_ClassOfWarrantOrRightAxis</ValueType><Namespace>xbrldi</Namespace><Schema>http://xbrl.org/2006/xbrldi</Schema><DimensionInfo><Id>us-gaap_WarrantMember</Id><dimensionId>us-gaap_ClassOfWarrantOrRightAxis</dimensionId><type>explicitMember</type></DimensionInfo></anyType><anyType xsi:type="Segment"><IsDefaultForEntity>false</IsDefaultForEntity><Name /><IsFromEntityGroup>false</IsFromEntityGroup><ValueName>Sancilio &amp; Company</ValueName><ValueType>us-gaap_CounterpartyNameAxis</ValueType><Namespace>xbrldi</Namespace><Schema>http://xbrl.org/2006/xbrldi</Schema><DimensionInfo><Id>txmd_SancilioMember</Id><dimensionId>us-gaap_CounterpartyNameAxis</dimensionId><type>explicitMember</type></DimensionInfo></anyType></Segments><Scenarios /></contextRef><UPS><UnitProperty><UnitID>Shares</UnitID><UnitType>Standard</UnitType><StandardMeasure><MeasureSchema>http://www.xbrl.org/2003/instance</MeasureSchema><MeasureValue>shares</MeasureValue><MeasureNamespace>xbrli</MeasureNamespace><MeasureDescription /><MeasureType /></StandardMeasure><Scale>0</Scale></UnitProperty></UPS><CurrencyCode /><OriginalCurrencyCode /></MCU><CurrencySymbol /><Labels><Label Key="CalendarSupplement" Id="0" Label="1 Months Ended" /><Label Key="Calendar" Id="1" Label="May 31, 2013" /><Label Key="us-gaap_ClassOfWarrantOrRightAxis:us-gaap_WarrantMember" Id="2" Label="Warrants" /><Label Key="us-gaap_CounterpartyNameAxis:txmd_SancilioMember" Id="3" Label="Sancilio &amp; Company" /></Labels></Column><Column FlagID="0"><Id>16</Id><IsAbstractGroupTitle>false</IsAbstractGroupTitle><LabelSeparator>

</LabelSeparator><CurrencyCode /><FootnoteIndexer /><hasSegments>true</hasSegments><hasScenarios>false</hasScenarios><MCU><KeyName /><CurrencySymbol>$</CurrencySymbol><contextRef><ContextID>AsOf2013-06-30_WarrantMember_MinimumMember</ContextID><EntitySchema>http://www.sec.gov/CIK</EntitySchema><EntityValue>0000025743</EntityValue><PeriodDisplayName /><PeriodType>instant</PeriodType><PeriodStartDate>2013-06-30T00:00:00</PeriodStartDate><PeriodEndDate>0001-01-01T00:00:00</PeriodEndDate><Segments><anyType xsi:type="Segment"><IsDefaultForEntity>false</IsDefaultForEntity><Name /><IsFromEntityGroup>false</IsFromEntityGroup><ValueName>Warrants</ValueName><ValueType>us-gaap_ClassOfWarrantOrRightAxis</ValueType><Namespace>xbrldi</Namespace><Schema>http://xbrl.org/2006/xbrldi</Schema><DimensionInfo><Id>us-gaap_WarrantMember</Id><dimensionId>us-gaap_ClassOfWarrantOrRightAxis</dimensionId><type>explicitMember</type></DimensionInfo></anyType><anyType xsi:type="Segment"><IsDefaultForEntity>false</IsDefaultForEntity><Name /><IsFromEntityGroup>false</IsFromEntityGroup><ValueName>Lower Range</ValueName><ValueType>us-gaap_RangeAxis</ValueType><Namespace>xbrldi</Namespace><Schema>http://xbrl.org/2006/xbrldi</Schema><DimensionInfo><Id>us-gaap_MinimumMember</Id><dimensionId>us-gaap_RangeAxis</dimensionId><type>explicitMember</type></DimensionInfo></anyType></Segments><Scenarios /></contextRef><UPS><UnitProperty><UnitID>USDPUnit</UnitID><UnitType>Divide</UnitType><NumeratorMeasure><MeasureSchema>http://www.xbrl.org/2003/iso4217</MeasureSchema><MeasureValue>USD</MeasureValue><MeasureNamespace>iso4217</MeasureNamespace><MeasureDescription /><MeasureType /></NumeratorMeasure><DenominatorMeasure><MeasureSchema>http://therapeuticsmd.com/20130630</MeasureSchema><MeasureValue>Unit</MeasureValue><MeasureNamespace>txmd</MeasureNamespace><MeasureDescription /><MeasureType /></DenominatorMeasure><Scale>0</Scale></UnitProperty></UPS><CurrencyCode>USD</CurrencyCode><OriginalCurrencyCode>USD</OriginalCurrencyCode></MCU><CurrencySymbol /><Labels><Label Key="Calendar" Id="0" Label="Jun. 30, 2013" /><Label Key="us-gaap_ClassOfWarrantOrRightAxis:us-gaap_WarrantMember" Id="1" Label="Warrants" /><Label Key="us-gaap_RangeAxis:us-gaap_MinimumMember" Id="2" Label="Lower Range" /></Labels></Column><Column FlagID="0"><Id>17</Id><IsAbstractGroupTitle>false</IsAbstractGroupTitle><LabelSeparator>

</LabelSeparator><CurrencyCode /><FootnoteIndexer /><hasSegments>true</hasSegments><hasScenarios>false</hasScenarios><MCU><KeyName /><CurrencySymbol>$</CurrencySymbol><contextRef><ContextID>AsOf2013-06-30_WarrantMember_MaximumMember</ContextID><EntitySchema>http://www.sec.gov/CIK</EntitySchema><EntityValue>0000025743</EntityValue><PeriodDisplayName /><PeriodType>instant</PeriodType><PeriodStartDate>2013-06-30T00:00:00</PeriodStartDate><PeriodEndDate>0001-01-01T00:00:00</PeriodEndDate><Segments><anyType xsi:type="Segment"><IsDefaultForEntity>false</IsDefaultForEntity><Name /><IsFromEntityGroup>false</IsFromEntityGroup><ValueName>Warrants</ValueName><ValueType>us-gaap_ClassOfWarrantOrRightAxis</ValueType><Namespace>xbrldi</Namespace><Schema>http://xbrl.org/2006/xbrldi</Schema><DimensionInfo><Id>us-gaap_WarrantMember</Id><dimensionId>us-gaap_ClassOfWarrantOrRightAxis</dimensionId><type>explicitMember</type></DimensionInfo></anyType><anyType xsi:type="Segment"><IsDefaultForEntity>false</IsDefaultForEntity><Name /><IsFromEntityGroup>false</IsFromEntityGroup><ValueName>Upper Range</ValueName><ValueType>us-gaap_RangeAxis</ValueType><Namespace>xbrldi</Namespace><Schema>http://xbrl.org/2006/xbrldi</Schema><DimensionInfo><Id>us-gaap_MaximumMember</Id><dimensionId>us-gaap_RangeAxis</dimensionId><type>explicitMember</type></DimensionInfo></anyType></Segments><Scenarios /></contextRef><UPS><UnitProperty><UnitID>USDPUnit</UnitID><UnitType>Divide</UnitType><NumeratorMeasure><MeasureSchema>http://www.xbrl.org/2003/iso4217</MeasureSchema><MeasureValue>USD</MeasureValue><MeasureNamespace>iso4217</MeasureNamespace><MeasureDescription /><MeasureType /></NumeratorMeasure><DenominatorMeasure><MeasureSchema>http://therapeuticsmd.com/20130630</MeasureSchema><MeasureValue>Unit</MeasureValue><MeasureNamespace>txmd</MeasureNamespace><MeasureDescription /><MeasureType /></DenominatorMeasure><Scale>0</Scale></UnitProperty></UPS><CurrencyCode>USD</CurrencyCode><OriginalCurrencyCode>USD</OriginalCurrencyCode></MCU><CurrencySymbol /><Labels><Label Key="Calendar" Id="0" Label="Jun. 30, 2013" /><Label Key="us-gaap_ClassOfWarrantOrRightAxis:us-gaap_WarrantMember" Id="1" Label="Warrants" /><Label Key="us-gaap_RangeAxis:us-gaap_MaximumMember" Id="2" Label="Upper Range" /></Labels></Column><Column FlagID="0"><Id>18</Id><IsAbstractGroupTitle>false</IsAbstractGroupTitle><LabelSeparator>

</LabelSeparator><CurrencyCode /><FootnoteIndexer /><hasSegments>true</hasSegments><hasScenarios>false</hasScenarios><MCU><KeyName /><CurrencySymbol>$</CurrencySymbol><contextRef><ContextID>From2012-06-18to2012-06-19_Debt7Member_Warrants1Member</ContextID><EntitySchema>http://www.sec.gov/CIK</EntitySchema><EntityValue>0000025743</EntityValue><PeriodDisplayName /><PeriodType>duration</PeriodType><PeriodStartDate>2012-06-18T00:00:00</PeriodStartDate><PeriodEndDate>2012-06-19T00:00:00</PeriodEndDate><Segments><anyType xsi:type="Segment"><IsDefaultForEntity>false</IsDefaultForEntity><Name /><IsFromEntityGroup>false</IsFromEntityGroup><ValueName>Warrants Tranche 1</ValueName><ValueType>us-gaap_ClassOfWarrantOrRightAxis</ValueType><Namespace>xbrldi</Namespace><Schema>http://xbrl.org/2006/xbrldi</Schema><DimensionInfo><Id>txmd_Warrants1Member</Id><dimensionId>us-gaap_ClassOfWarrantOrRightAxis</dimensionId><type>explicitMember</type></DimensionInfo></anyType><anyType xsi:type="Segment"><IsDefaultForEntity>false</IsDefaultForEntity><Name /><IsFromEntityGroup>false</IsFromEntityGroup><ValueName>Promissory Notes - June 2012 Notes Issuance</ValueName><ValueType>us-gaap_LongtermDebtTypeAxis</ValueType><Namespace>xbrldi</Namespace><Schema>http://xbrl.org/2006/xbrldi</Schema><DimensionInfo><Id>txmd_Debt7Member</Id><dimensionId>us-gaap_LongtermDebtTypeAxis</dimensionId><type>explicitMember</type></DimensionInfo></anyType></Segments><Scenarios /></contextRef><UPS><UnitProperty><UnitID>Shares</UnitID><UnitType>Standard</UnitType><StandardMeasure><MeasureSchema>http://www.xbrl.org/2003/instance</MeasureSchema><MeasureValue>shares</MeasureValue><MeasureNamespace>xbrli</MeasureNamespace><MeasureDescription /><MeasureType /></StandardMeasure><Scale>0</Scale></UnitProperty><UnitProperty><UnitID>USDPUnit</UnitID><UnitType>Divide</UnitType><NumeratorMeasure><MeasureSchema>http://www.xbrl.org/2003/iso4217</MeasureSchema><MeasureValue>USD</MeasureValue><MeasureNamespace>iso4217</MeasureNamespace><MeasureDescription /><MeasureType /></NumeratorMeasure><DenominatorMeasure><MeasureSchema>http://therapeuticsmd.com/20130630</MeasureSchema><MeasureValue>Unit</MeasureValue><MeasureNamespace>txmd</MeasureNamespace><MeasureDescription /><MeasureType /></DenominatorMeasure><Scale>0</Scale></UnitProperty></UPS><CurrencyCode>USD</CurrencyCode><OriginalCurrencyCode>USD</OriginalCurrencyCode></MCU><CurrencySymbol /><Labels><Label Key="CalendarSupplement" Id="0" Label="0 Months Ended" /><Label Key="Calendar" Id="1" Label="Jun. 19, 2012" /><Label Key="us-gaap_ClassOfWarrantOrRightAxis:txmd_Warrants1Member" Id="2" Label="Warrants Tranche 1" /><Label Key="us-gaap_LongtermDebtTypeAxis:txmd_Debt7Member" Id="3" Label="Promissory Notes - June 2012 Notes Issuance" /></Labels></Column><Column FlagID="0"><Id>19</Id><IsAbstractGroupTitle>false</IsAbstractGroupTitle><LabelSeparator>

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 -Publisher FASB

 -Name Accounting Standards Codification

 -Topic 235

 -SubTopic 10

 -Section S99

 -Paragraph 1

 -Subparagraph (SX 210.4-08.(i))

 -URI http://asc.fasb.org/extlink&amp;oid=26873400&amp;loc=d3e23780-122690



Reference 2: http://www.xbrl.org/2003/role/presentationRef

 -Publisher SEC

 -Name Regulation S-X (SX)

 -Number 210

 -Section 08

 -Paragraph i

 -Article 4



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 -Publisher FASB

 -Name Accounting Standards Codification

 -Topic 235

 -SubTopic 10

 -Section S99

 -Paragraph 1

 -Subparagraph (SX 210.4-08.(i)(4))

 -URI http://asc.fasb.org/extlink&amp;oid=26873400&amp;loc=d3e23780-122690



Reference 2: http://www.xbrl.org/2003/role/presentationRef

 -Publisher SEC

 -Name Regulation S-X (SX)

 -Number 210

 -Section 08

 -Paragraph i

 -Subparagraph 4

 -Article 4



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 -Publisher FASB

 -Name Accounting Standards Codification

 -Topic 820

 -SubTopic 10

 -Section 50

 -Paragraph 2

 -Subparagraph (e)

 -URI http://asc.fasb.org/extlink&amp;oid=25499696&amp;loc=d3e19207-110258



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 -Publisher FASB

 -Name Accounting Standards Codification

 -Topic 820

 -SubTopic 10

 -Section 50

 -Paragraph 2

 -Subparagraph (e)

 -URI http://asc.fasb.org/extlink&amp;oid=25499696&amp;loc=d3e19207-110258



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 -Publisher FASB

 -Name Accounting Standards Codification

 -Topic 820

 -SubTopic 10

 -Section 50

 -Paragraph 2

 -Subparagraph (e)

 -URI http://asc.fasb.org/extlink&amp;oid=25499696&amp;loc=d3e19207-110258



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 -Publisher FASB

 -Name Accounting Standards Codification

 -Topic 820

 -SubTopic 10

 -Section 50

 -Paragraph 2

 -Subparagraph (e)

 -URI http://asc.fasb.org/extlink&amp;oid=25499696&amp;loc=d3e19207-110258



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 -Publisher FASB

 -Name Accounting Standards Codification

 -Topic 718

 -SubTopic 10

 -Section 50

 -Paragraph 2

 -Subparagraph (c)(1)(iv)(3)

 -URI http://asc.fasb.org/extlink&amp;oid=6415400&amp;loc=d3e5070-113901



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 -Publisher FASB

 -Name Accounting Standards Codification

 -Topic 718

 -SubTopic 10

 -Section 50

 -Paragraph 2

 -Subparagraph (c)(1)(iv)(1)

 -URI http://asc.fasb.org/extlink&amp;oid=6415400&amp;loc=d3e5070-113901



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The term is often expanded to include other professions, for example, pharmacists charging to maintain a medicinal profile of a client or customer.</ElementDefenition><ElementReferences>Reference 1: http://www.xbrl.org/2003/role/presentationRef

 -Publisher FASB

 -Name Accounting Standards Codification

 -Topic 946

 -SubTopic 225

 -Section S99

 -Paragraph 1

 -Subparagraph (SX 210.6-07.2(a),(b),(c),(d))

 -URI http://asc.fasb.org/extlink&amp;oid=6488393&amp;loc=d3e606610-122999



Reference 2: http://www.xbrl.org/2003/role/presentationRef

 -Publisher FASB

 -Name Accounting Standards Codification

 -Topic 946

 -SubTopic 225

 -Section 45

 -Paragraph 3

 -Subparagraph (k)

 -URI http://asc.fasb.org/extlink&amp;oid=6488370&amp;loc=d3e13550-115849



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