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STOCKHOLDERS' EQUITY (Details Narrative) (USD $)
 0 Months Ended 12 Months Ended 0 Months Ended 1 Months Ended 0 Months Ended 1 Months Ended 2 Months Ended 0 Months Ended 12 Months Ended 0 Months Ended
Jul. 28, 2011
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2011
Jul. 29, 2011
Oct. 05, 2011
Stock Purchase Agreement With Pernix Therapeutics LLC
Sep. 30, 2013
Private placement
Jun. 19, 2012
February 2012 Notes/ Warrants
Jun. 30, 2013
February 2012 Notes/ Warrants
Dec. 31, 2011
VitaMed Promissory Notes
Nov. 30, 2011
VitaMed Promissory Notes
Oct. 30, 2011
VitaMed Promissory Notes
Number
Oct. 31, 2011
VitaMed Promissory Notes
Nov. 30, 2011
VitaMed Promissory Notes
Apr. 20, 2013
Jefferies LLC (Underwriters)
Mar. 20, 2013
Jefferies LLC (Underwriters)
Dec. 31, 2013
Jefferies LLC (Underwriters)
Sep. 25, 2013
Stifel, Nicolaus & Company (Underwriters)
Preferred stock, shares authorized   10,000,000 10,000,000                              
Preferred stock, par value (in dollars per share)   $ 0.001 $ 0.001                              
Preferred stock, shares issued   0 0                              
Preferred stock, shares outstanding   0 0                              
Common stock, shares authorized   250,000,000 250,000,000                              
Common stock, shares issued 16,575,209 144,976,757 99,784,982   165,856                          
Common stock, shares outstanding 16,575,209 144,976,757 99,784,982   165,856                          
Number of shares issued during the period           2,631,579 3,953,489                   29,411,765 13,750,000
Share price (in dollars per share)             $ 2.15                   $ 1.70 $ 2.40
Share price to underwritters (in dollars per share)           $ 0.38                     $ 1.58 $ 2.23
Number of shares issued during the period,value   $ 78,650,353 $ 7,895,485 $ 1,707,000   $ 1,000,000 $ 7,895,485                   $ 45,400,000 $ 30,200,000
Additional period for purchase share                                 30 days  
Total Additional common stock issued under shelf registration statement                               4,411,765    
Additional common stock issued under shelf registration statement                             1,954,587      
Additional common stock issued under shelf registration statement,value                             3,100,000      
Numbers of options to purchase shares of common stock exercised for cash     1,691,393                              
Options to purchase shares of common stock, value   30,910 191,000 17,250           17,250                
Numbers of options to purchase shares of common stock, cashless exercise     240,395                              
Number of shares issued in exercise of warrants     3,102,000           3,102,000                  
Amount of shares issued in exercise of warrants               8,145,486 8,145,486                  
Value of debt converted to shares      (6,716,504)            1,054,647     100,000   849,137        
Numbers of shares converted for debt                 2,775,415   1,415,136 266,822 20,266,822          
Conversion price (in dollars per share)                 $ 0.38     $ 0.38            
Transaction cash fees             552,500                      
Legal fees and expenses paid             52,016                      
Aggregate purchase price of common stock sold             $ 8,500,001                      
Reverse stock split ratio 1 for 100