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CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($) | 12 Months Ended
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Dec. 31, 2016 | Dec. 31, 2015 | Dec. 31, 2014
Income Statement [Abstract] |  |  |
Revenues, net | $ 19,356,450 | $ 20,142,898 | $ 15,026,219
Cost of goods sold | 4,185,708 | 4,506,673 | 3,671,803
Gross profit | 15,170,742 | 15,636,225 | 11,354,416
Operating expenses: |  |  |
Sales, general, and administrative | 51,348,414 | 28,721,236 | 22,124,072
Research and development | 53,943,477 | 72,042,774 | 43,218,938
Depreciation and amortization | 132,451 | 62,400 | 52,467
Total operating expenses | 105,424,342 | 100,826,410 | 65,395,477
Operating loss | (90,253,600) | (85,190,185) | (54,041,061)
Other income and (expense) |  |  |
Miscellaneous income | 367,317 | 95,719 | 46,569
Accreted interest | 10,824 | 17,442 | 37,309
Financing costs |  |  | (260,027)
Total other income (expense) | 378,141 | 113,161 | (176,149)
Loss before income taxes | (89,875,459) | (85,077,024) | (54,217,210)
Net loss | $ (89,875,459) | $ (85,077,024) | $ (54,217,210)
Loss per share, basic and diluted: |  |  |
Net loss per share, basic and diluted | $ (0.46) | $ (0.49) | $ (0.36)
Weighted average number of common shares outstanding, basic and diluted | 196,088,196 | 173,174,229 | 149,727,228

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