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STOCKHOLDERS' EQUITY (Details Narrative) - USD ($) |  |  |  |  |  |  |  |  | 12 Months Ended
--- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Sep. 28, 2017 | Sep. 25, 2017 | Jan. 12, 2016 | Jan. 06, 2016 | Jul. 15, 2015 | Jul. 09, 2015 | Feb. 17, 2015 | Feb. 10, 2015 | Dec. 31, 2017 | Dec. 31, 2016 | Dec. 31, 2015
Preferred stock, par value (in dollars per share) |  |  |  |  |  |  |  |  | $ 0.001 | $ 0.001 |
Preferred stock, shares authorized |  |  |  |  |  |  |  |  | 10,000,000 | 10,000,000 |
Preferred stock, shares issued |  |  |  |  |  |  |  |  | 0 | 0 |
Preferred stock, shares outstanding |  |  |  |  |  |  |  |  | 0 | 0 |
Common stock, shares authorized |  |  |  |  |  |  |  |  | 350,000,000 | 350,000,000 |
Common stock, shares issued |  |  |  |  |  |  |  |  | 216,429,642 | 196,688,222 |
Common stock, shares outstanding |  |  |  |  |  |  |  |  | 216,429,642 | 196,688,222 |
Value of common stock issued during period for stock options exercised |  |  |  |  |  |  |  |  | $ 212,615 | $ 989,060 | $ 1,232,579
Number of stock options exercised (in shares) |  |  |  |  |  |  |  |  | 102,546 | 523,362 |
Proceeds from sale of common stock, net of costs |  |  |  |  |  |  |  |  | $ 68,572,635 | $ 134,863,475 | 91,374,649
Number of stock options exercised in cashless exercise (in shares) |  |  |  |  |  |  |  |  |  | 127,109 |
Number of common stock issued during period for stock options exercised in cashless exercise (in shares) |  |  |  |  |  |  |  |  |  | 87,833 |
Stock Options [Member] |  |  |  |  |  |  |  |  |  |  |
Value of common stock issued during period for stock options exercised |  |  |  |  |  |  |  |  |  |  | $ 1,232,579
Number of stock options exercised (in shares) |  |  |  |  |  |  |  |  |  |  | 612,867
Number of stock options exercised in cashless exercise (in shares) |  |  |  |  |  |  |  |  |  |  | 417
Number of common stock issued during period for stock options exercised in cashless exercise (in shares) |  |  |  |  |  |  |  |  |  |  | 114
Underwriting Agreement - J.P. Morgan Securities LLC [Member] |  |  |  |  |  |  |  |  |  |  |
Number of shares offered in underwriting agreement |  | 12,400,000 |  |  |  |  |  |  |  |  |
Number of shares issued during the period | 12,400,000 |  |  |  |  |  |  |  |  |  |
Share price (in dollars per share) |  | $ 5.55 |  |  |  |  |  |  |  |  |
Proceeds from sale of common stock, net of costs |  | $ 68,573,000 |  |  |  |  |  |  |  |  |
Underwriting Agreement - Goldman and Cowen [Member] |  |  |  |  |  |  |  |  |  |  |
Number of shares offered in underwriting agreement |  |  |  | 15,151,515 |  |  |  |  |  |  |
Number of shares issued during the period |  |  | 17,424,242 |  |  |  |  |  |  |  |
Share price (in dollars per share) |  |  |  | $ 8.25 |  |  |  |  |  |  |
Proceeds from sale of common stock, net of costs |  |  |  | $ 134,864,000 |  |  |  |  |  |  |
Additional common stock issued under offering |  |  |  | 2,272,727 |  |  |  |  |  |  |
Number of days of the option to purchase shares |  |  |  | 30 days |  |  |  |  |  |  |
Stifel Underwriters [Member] |  |  |  |  |  |  |  |  |  |  |
Number of shares offered in underwriting agreement |  |  |  |  |  | 3,846,154 |  |  |  |  |
Number of shares issued during the period |  |  |  |  | 4,423,077 |  |  |  |  |  |
Share price (in dollars per share) |  |  |  |  |  | $ 7.80 |  |  |  |  |
Proceeds from sale of common stock, net of costs |  |  |  |  |  | $ 32,257,000 |  |  |  |  |
Additional common stock issued under offering |  |  |  |  |  | 576,923 |  |  |  |  |
Number of days of the option to purchase shares |  |  |  |  |  | 30 days |  |  |  |  |
Cowen and Company, LLC (Underwriters) [Member] |  |  |  |  |  |  |  |  |  |  |
Number of shares offered in underwriting agreement |  |  |  |  |  |  |  | 13,580,246 |  |  |
Number of shares issued during the period |  |  |  |  |  |  | 15,617,282 |  |  |  |
Share price (in dollars per share) |  |  |  |  |  |  |  | $ 4.05 |  |  |
Proceeds from sale of common stock, net of costs |  |  |  |  |  |  |  | $ 59,118,000 |  |  |
Additional common stock issued under offering |  |  |  |  |  |  |  | 2,037,036 |  |  |
Number of days of the option to purchase shares |  |  |  |  |  |  |  | 30 days |  |  |

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