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CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($)
 12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Income Statement [Abstract]      
Revenues, net $ 16,777,713 $ 19,356,450 $ 20,142,898
Cost of goods sold 2,636,943 4,185,708 4,506,673
Gross profit 14,140,770 15,170,742 15,636,225
Operating expenses:      
Sales, general, and administration 57,703,370 51,348,414 28,721,236
Research and development 33,852,993 53,943,477 72,042,774
Depreciation and amortization 213,117 132,451 62,400
Total operating expense 91,769,480 105,424,342 100,826,410
Operating loss (77,628,710) (90,253,600) (85,190,185)
Other income:      
Miscellaneous income 695,631 367,317 95,719
Accreted interest 7,699 10,824 17,442
Total other income 703,330 378,141 113,161
Loss before taxes (76,925,380) (89,875,459) (85,077,024)
Net loss $ (76,925,380) $ (89,875,459) $ (85,077,024)
Net loss per share, basic and diluted (in dollars per share) $ (0.37) $ (0.46) $ (0.49)
Weighted average number of common shares outstanding (in shares) 205,523,288 196,088,196 173,174,229