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v3.19.1

INTANGIBLE ASSETS (Details Narrative) |  |  | 3 Months Ended
--- | --- | --- | ---
Aug. 06, 2018 USD ($) $ / shares shares | Jul. 30, 2018 USD ($) | Mar. 31, 2019 USD ($) Number | Mar. 31, 2018 USD ($)
Finite-Lived Intangible Assets [Line Items] |  |  |  |
Amortization expense | $ |  |  | $ 40,444 | $ 21,197
Subscription Agreement [Member] | Knight Therapeutics Inc. [Member] |  |  |  |
Finite-Lived Intangible Assets [Line Items] |  |  |  |
Issue of common stock shares (in shares) | shares | 3,921,568 |  |  |
Common stock sale price (in dollars per share) | $ / shares | $ 5.10 |  |  |
Gross proceeds | $ | $ 20,000,000 |  |  |
Approved Hormone Therapy Drug Candidate Patents [Member] |  |  |  |
Finite-Lived Intangible Assets [Line Items] |  |  |  |
Useful Life |  |  | 20 years |
Domestic U.S. Patents [Member] |  |  |  |
Finite-Lived Intangible Assets [Line Items] |  |  |  |
Number of issued patents |  |  | 22 |
Foreign Patents [Member] |  |  |  |
Finite-Lived Intangible Assets [Line Items] |  |  |  |
Number of issued patents |  |  | 27 |
Domestic Utility Patents [Member] |  |  |  |
Finite-Lived Intangible Assets [Line Items] |  |  |  |
Number of issued patents |  |  | 12 |
Foreign Utility Patents [Member] |  |  |  |
Finite-Lived Intangible Assets [Line Items] |  |  |  |
Number of issued patents |  |  | 5 |
Domestic Patents - TX-004HR [Member] |  |  |  |
Finite-Lived Intangible Assets [Line Items] |  |  |  |
Number of issued patents |  |  | 3 |
Foreign Patents - TX-004HR [Member] |  |  |  |
Finite-Lived Intangible Assets [Line Items] |  |  |  |
Number of issued patents |  |  | 13 |
Domestic Utility Patent - Transdermal Patch Candidates [Member] |  |  |  |
Finite-Lived Intangible Assets [Line Items] |  |  |  |
Number of issued patents |  |  | 1 |
Foreign Utility Patent - Transdermal Patch Candidates [Member] |  |  |  |
Finite-Lived Intangible Assets [Line Items] |  |  |  |
Number of issued patents |  |  | 5 |
Domestic Utilty Patent - Opera Software [Member] |  |  |  |
Finite-Lived Intangible Assets [Line Items] |  |  |  |
Number of issued patents |  |  | 1 |
Domestic Utility Patents Topical - Cream Candidates [Member] |  |  |  |
Finite-Lived Intangible Assets [Line Items] |  |  |  |
Number of issued patents |  |  | 1 |
Domestic Patents - TX-009HR [Member] |  |  |  |
Finite-Lived Intangible Assets [Line Items] |  |  |  |
Number of issued patents |  |  | 1 |
Foreign Patents Progesterone - Only Candidate [Member] |  |  |  |
Finite-Lived Intangible Assets [Line Items] |  |  |  |
Number of issued patents |  |  | 5 |
Domestic Patents - TX-009HR [Member] |  |  |  |
Finite-Lived Intangible Assets [Line Items] |  |  |  |
Number of issued patents |  |  | 1 |
Foreign Patents Progesterone - Only Candidate [Member] |  |  |  |
Finite-Lived Intangible Assets [Line Items] |  |  |  |
Number of issued patents |  |  | 4 |
Council License Agreement [Member] |  |  |  |
Finite-Lived Intangible Assets [Line Items] |  |  |  |
Payment of milestone recorded as finite-lived intangible asset | $ |  | $ 20,000,000 |  |
Council License Agreement [Member] | ANNOVERA [Member] |  |  |  |
Finite-Lived Intangible Assets [Line Items] |  |  |  |
Milestone payments upon FDA approval | $ |  |  | $ 20,000,000 |
Milestone payments (payment after release of first commercial batch) | $ |  |  | $ 20,000,000 |
Annual royalty rate reduction of initial rate during the six-month period from commercial sale of a generic equivalent |  |  | 50.00% |
Annual royalty rate reduction of initial rate after the six-month period from commercial sale of a generic equivalent |  |  | 20.00% |
Maximum costs and expenses for post approval study to be paid by the Company | $ |  |  | $ 20,000,000 |
Council License Agreement [Member] | ANNOVERA [Member] | Step-based Royalty Payment One [Member] |  |  |  |
Finite-Lived Intangible Assets [Line Items] |  |  |  |
Royalty (percent) |  |  | 5.00% |
Council License Agreement [Member] | ANNOVERA [Member] | Step-based Royalty Payment One [Member] | Maximum [Member] |  |  |  |
Finite-Lived Intangible Assets [Line Items] |  |  |  |
Net sales amount per step-based royalty | $ |  |  | $ 50,000,000 |
Council License Agreement [Member] | ANNOVERA [Member] | Step-based Royalty Payment Three [Member] |  |  |  |
Finite-Lived Intangible Assets [Line Items] |  |  |  |
Royalty (percent) |  |  | 15.00% |
Council License Agreement [Member] | ANNOVERA [Member] | Step-based Royalty Payment Three [Member] | Minimum [Member] |  |  |  |
Finite-Lived Intangible Assets [Line Items] |  |  |  |
Net sales amount per step-based royalty | $ |  |  | $ 150,000,000 |
Council License Agreement [Member] | ANNOVERA [Member] | Step-based Royalty Payment Two [Member] |  |  |  |
Finite-Lived Intangible Assets [Line Items] |  |  |  |
Royalty (percent) |  |  | 10.00% |
Council License Agreement [Member] | ANNOVERA [Member] | Step-based Royalty Payment Two [Member] | Minimum [Member] |  |  |  |
Finite-Lived Intangible Assets [Line Items] |  |  |  |
Net sales amount per step-based royalty | $ |  |  | $ 50,000,000 |
Council License Agreement [Member] | ANNOVERA [Member] | Step-based Royalty Payment Two [Member] | Maximum [Member] |  |  |  |
Finite-Lived Intangible Assets [Line Items] |  |  |  |
Net sales amount per step-based royalty | $ |  |  | $ 150,000,000 |

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