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A summary of activity under the 2009, 2012 and 2019 Plans and related information follows: (Details) - USD ($)
3 Months Ended 9 Months Ended 12 Months Ended
Sep. 30, 2019
Sep. 30, 2018
Sep. 30, 2019
Sep. 30, 2018
Dec. 31, 2018
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Exercised 55,236 1,052,300 331,619 1,446,876  
Vested and Exercisable     4 years 292 days    
Unvested     9 years 21 days 21 hours 36 minutes    
Share-based Payment Arrangement, Option [Member]          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Balance, beginning     20,872,824    
Balance, beginning     $ 4.93    
Balance, ending     6 years 18 days 6 hours   5 years 343 days 2 hours 24 minutes
Balance, beginning     $ 12,239,876    
Granted     4,419,501    
Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price     $ 3.13    
Exercised     343,716    
Share-based Compensation Arrangements by Share-based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price     $ 0.32    
Exercised     $ 1,426,828    
Expired Forfeited     98,625    
Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures and Expirations in Period, Weighted Average Exercise Price     $ 5.63    
Balance, ending 24,849,984   24,849,984   20,872,824
Balance, ending $ 4.67   $ 4.67   $ 4.93
Balance, ending $ 13,761,778   $ 13,761,778   $ 12,239,876
Vested and Exercisable 17,601,027   17,601,027    
Vested and Exercisable $ 4.85   $ 4.85    
Vested and Exercisable $ 9,745,527   $ 9,745,527    
Unvested 7,248,957   7,248,957    
Unvested $ 4.22   $ 4.22    
Unvested $ 4,016,251   $ 4,016,251