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Summarized quarterly financial data for fiscal years 2019 and 2018 is as follows: (Details) - USD ($) | 3 Months Ended | 12 Months Ended
--- | --- | ---
Dec. 31, 2019 | Sep. 30, 2019 | Jun. 30, 2019 | Mar. 31, 2019 | Dec. 31, 2018 | Sep. 30, 2018 | Jun. 30, 2018 | Mar. 31, 2018 | Dec. 31, 2019 | Dec. 31, 2018 | Dec. 31, 2017
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |
Revenues | $ 15,902,000 | $ 23,719,000 | $ 6,079,000 | $ 3,947,000 | $ 5,089,000 | $ 3,474,000 | $ 3,763,000 | $ 3,773,000 | $ 49,646,937 | $ 16,099,460 | $ 16,777,713
Gross profit | 13,023,000 | 22,275,000 | 4,830,000 | 3,184,000 | 4,139,000 | 2,775,000 | 3,309,000 | 3,139,000 | 43,312,352 | 13,361,808 | 14,140,770
Net loss | $ (49,435,000) | $ (31,967,000) | $ (55,237,000) | $ (39,506,000) | $ (39,391,000) | $ (35,605,000) | $ (33,219,000) | $ (24,402,000) | $ (176,144,999) | $ (132,617,160) | $ (76,925,380)
Loss per common share, basic and diluted | $ (0.19) | $ (0.13) | $ (0.23) | $ (0.16) | $ (0.17) | $ (0.16) | $ (0.15) | $ (0.11) | $ (0.72) | $ (0.59) | $ (0.37)
Loss on extinguishment of debt |  |  | $ 10,100,000 |  |  |  |  |  | $ 10,057,632 |  |
License Agreement Theramex |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |
Revenues |  | $ 15,500,000 |  |  |  |  |  |  |  |  |

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