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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
 12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
CASH FLOWS FROM OPERATING ACTIVITIES      
Net loss $ (183,524,137) $ (176,144,999) $ (132,617,160)
Adjustments to reconcile net loss to net cash used in operating activities:      
Depreciation of fixed assets 772,624 415,193 181,412
Amortization of intangible assets 269,546 197,593 112,474
Write off of patent and trademark cost 1,131,776 78,864
Write off of deferred financing fees 275,379
Non-cash operating lease expense 1,405,443 1,062,318
Provision for doubtful accounts 213,814 307,438 216,022
Lease impairment 136,832
Inventory Write-down 7,204,818 0  
Loss of extinguishment of debt 10,057,632
Share-based compensation 10,678,992 10,693,662 8,661,967
Amortization of intellectual property license fee 3,024,391 778,692
Amortization of deferred financing costs 2,256,429 856,302 269,859
Changes in operating assets and liabilities:      
 Accounts receivable (8,199,558) (13,639,575) (6,951,041)
 Inventory (3,337,189) (8,593,046) (1,782,312)
 Other assets 3,429,443 (1,880,048) (2,657,190)
Accounts payable 1,887,115 (3,562,629) 18,646,241
Accrued expenses and other liabilities 2,903,947 13,675,008 9,107,947
Net cash used in operating activities (159,470,335) (165,697,595) (106,811,781)
CASH FLOWS FROM INVESTING ACTIVITIES      
Payment for intellectual property license (20,000,000) (20,000,000)
Patent costs (1,390,834) (1,441,989) (1,105,407)
Purchase of fixed assets (207,073) (2,450,285) (217,040)
Payment of security deposit (20,420) (175,410)
Net cash used in investing activities (1,597,907) (23,912,694) (21,497,857)
CASH FLOWS FROM FINANCING ACTIVITIES      
Proceeds from exercise of options and warrants 271,678 108,656 1,666,208
Proceeds from sale of common stock, net of costs 31,702,635 77,031,258 89,907,797
Proceeds from Financing Agreement 50,000,000 200,000,000
Proceeds from Credit Agreement 75,000,000
Payment of deferred financing fees (1,250,000) (6,652,270) (3,786,918)
Repayment of Credit Agreement (81,660,719)
Net cash provided by financing activities 80,724,313 188,826,925 162,787,087
(Decrease) increase in cash (80,343,929) (783,364) 34,477,449
Cash, beginning of period 160,829,713 161,613,077 127,135,628
Cash, end of period 80,485,784 160,829,713 161,613,077
Supplemental disclosure of cash flow information      
Interest paid 25,849,236 17,787,903 1,890,166
Non-cash investing activity      
Warrant granted in relation to Financing Agreement $ 7,668,161