A member of our Board

of Directors, J. Martin Carrol, is also a director of Catalent. From time to time, we have entered into agreements with Catalent and its affiliates in the normal course of business. Agreements with Catalent have been reviewed by independent directors of our Company, or a committee consisting of independent directors of our Company. During the three months ended March

2021

and

2020

, we were billed by Catalent of $

772

thousand and $

1.3

million, respectively, for manufacturing activities. As of March

2021

and December

2020

, we have

estimated

amounts payable to Catalent totaling $

639

thousand and $

276

thousand, respectively. In addition, we have minimum purchase requirements in place with Catalent as disclosed in Note

, Commitments and contingencies.

A member of our Board of Directors, Karen L. Ling, is an executive vice president and chief human resources officer of American International Group, Inc. (“AIG”). From time to time, we have entered into agreements with AIG in the normal course of business. Agreements with AIG have been reviewed by independent directors of our Company, or a committee consisting of independent directors of our Company. During the three months ended March 31, 2021 and 2020, we were billed by AIG of $13 thousand and $71 thousand, respectively, for various insurance premiums. As of March 31, 2021 and December 31, 2020, we have no amounts payable to AIG.