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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2021
Mar. 31, 2020
Cash flows from operating activities:    
Net loss $ (39,383) $ (56,849)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 1,019 1,008
Charges (credits) to provision for doubtful accounts 230 (123)
Inventory charge 502 136
Debt financing fees 1,272 320
Non-cash operating lease expense 216 352
Share-based compensation 2,957 2,366
Changes in operating assets and liabilities:    
Accounts receivable (1,567) 3,855
Inventory 145 (2,883)
Prepaid and other current assets (817) 4,436
Accounts payable (10,758) 9,533
Accrued expenses and other current liabilities 7,804 (1,262)
Total adjustments 1,003 17,738
Net cash used in operating activities (38,380) (39,111)
Cash flows from investing activities:    
Payment of patent related costs (375) (422)
Purchase of fixed assets (63) (21)
Net cash used in investing activities (438) (443)
Cash flows from financing activities:    
Proceeds from sale of common stock, net of costs 150,899  
Proceeds from exercise of options and warrants 50 72
Repayments of debt (50,000)  
Borrowings of debt   50,000
Payment of debt financing fees (5,000) (1,250)
Net cash provided by financing activities 95,949 48,822
Net increase in cash 57,131 9,268
Cash, beginning of period 80,486 160,830
Cash, end of period 137,617 170,098
Supplemental disclosure of cash flow information:    
Interest paid $ 8,955 $ 5,893