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CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY (DEFICIT) - USD ($) $ in Thousands | Total | Common Stock [Member] | Additional Paid-in Capital [Member] | Accumulated Deficit [Member]
--- | --- | --- | --- | ---
Beginning balance, value at Dec. 31, 2019 | $ 9,201 | $ 271 | $ 704,351 | $ (695,421)
Beginning balance, shares at Dec. 31, 2019 |  | 271,177,000 |  |
Shares issued for exercise of options | 72 |  | 72 |
Shares issued for exercise of options (in shares) |  | 351,000 |  |
Shares issued for vested restricted stock units (in shares) |  | 150,000 |  |
Share-based compensation | 2,366 |  | 2,366 |
Net loss | (56,849) |  |  | (56,849)
Ending balance, value at Mar. 31, 2020 | (45,210) | $ 271 | 706,789 | (752,270)
Ending balance, shares at Mar. 31, 2020 |  | 271,678,000 |  |
Beginning balance, value at Dec. 31, 2019 | 9,201 | $ 271 | 704,351 | (695,421)
Beginning balance, shares at Dec. 31, 2019 |  | 271,177,000 |  |
Net loss | (141,437) |  |  |
Ending balance, value at Sep. 30, 2020 | (116,033) | $ 273 | 720,552 | (836,858)
Ending balance, shares at Sep. 30, 2020 |  | 272,812,000 |  |
Beginning balance, value at Mar. 31, 2020 | (45,210) | $ 271 | 706,789 | (752,270)
Beginning balance, shares at Mar. 31, 2020 |  | 271,678,000 |  |
Shares issued for exercise of options | 95 | $ 1 | 94 |
Shares issued for exercise of options (in shares) |  | 313,000 |  |
Shares issued for vested restricted stock units (in shares) |  | 303,000 |  |
Share-based compensation | 3,003 |  | 3,003 |
Net loss | (51,976) |  |  | (51,976)
Ending balance, value at Jun. 30, 2020 | (94,088) | $ 272 | 709,886 | (804,246)
Ending balance, shares at Jun. 30, 2020 |  | 272,294,000 |  |
Shares issued for exercise of warrants and options, net of cashless exercises | 106 | $ 1 | 105 |
Shares issued for exercise of warrants and options, net of cashless exercises (in shares) |  | 518,000 |  |
Warrants issued in relation to debt financing agreement | 7,428 |  | 7,428 |
Share-based compensation | 3,133 |  | 3,133 |
Net loss | (32,612) |  |  | (32,612)
Ending balance, value at Sep. 30, 2020 | (116,033) | $ 273 | 720,552 | (836,858)
Ending balance, shares at Sep. 30, 2020 |  | 272,812,000 |  |
Beginning balance, value at Dec. 31, 2020 | $ (124,001) | $ 300 | 754,644 | (878,945)
Beginning balance, shares at Dec. 31, 2020 | 299,765,000 | 299,765,000 |  |
Shares issued for sale of common stock, net of cost, value | $ 150,899 | $ 93 | 150,806 |
Shares issued for sale of common stock, net of cost, shares |  | 92,870,000 |  |
Shares issued for exercise of warrants and options, net of cashless exercises | 50 |  | 50 |
Shares issued for exercise of warrants and options, net of cashless exercises (in shares) |  | 503,000 |  |
Shares issued for vested restricted stock units (in shares) |  | 52,000 |  |
Share-based compensation | 2,957 |  | 2,957 |
Net loss | (39,383) |  |  | (39,383)
Ending balance, value at Mar. 31, 2021 | (9,478) | $ 393 | 908,457 | (918,328)
Ending balance, shares at Mar. 31, 2021 |  | 393,190,000 |  |
Beginning balance, value at Dec. 31, 2020 | $ (124,001) | $ 300 | 754,644 | (878,945)
Beginning balance, shares at Dec. 31, 2020 | 299,765,000 | 299,765,000 |  |
Shares issued for exercise of options (in shares) | 61,000 |  |  |
Net loss | $ (129,455) |  |  |
Ending balance, value at Sep. 30, 2021 | $ (57,360) | $ 425 | 950,615 | (1,008,400)
Ending balance, shares at Sep. 30, 2021 | 424,879,000 | 424,879,000 |  |
Beginning balance, value at Mar. 31, 2021 | $ (9,478) | $ 393 | 908,457 | (918,328)
Beginning balance, shares at Mar. 31, 2021 |  | 393,190,000 |  |
Shares issued for sale of common stock, net of cost, value | 163 |  | 163 |
Shares issued for sale of common stock, net of cost, shares |  | 125,000 |  |
Shares issued for exercise of warrants and options, net of cashless exercises | 228 | $ 1 | 227 |
Shares issued for exercise of warrants and options, net of cashless exercises (in shares) |  | 600,000 |  |
Shares issued for exercise of options | 21 |  | 21 |
Shares issued for exercise of options (in shares) |  | 54,000 |  |
Shares issued for vested restricted stock units |  | $ 1 | (1) |
Shares issued for vested restricted stock units (in shares) |  | 929,000 |  |
Shares issued for sale of common stock related to employee stock purchase plan | 134 |  | 134 |
Shares issued for sale of common stock related to employee stock purchase plan (in shares) |  | 150,000 |  |
Share-based compensation | 2,510 |  | 2,510 |
Net loss | (42,652) |  |  | (42,652)
Ending balance, value at Jun. 30, 2021 | (49,074) | $ 395 | 911,511 | (960,980)
Ending balance, shares at Jun. 30, 2021 |  | 395,048,000 |  |
Shares issued for sale of common stock, net of cost, value | 31,819 | $ 29 | 31,790 |
Shares issued for sale of common stock, net of cost, shares |  | 28,770,000 |  |
Shares issued for exercise of options | 3 |  | 3 |
Shares issued for exercise of options (in shares) |  | 7,000 |  |
Shares issued for vested restricted stock units |  | $ 1 | (1) |
Shares issued for vested restricted stock units (in shares) |  | 1,054,000 |  |
Share-based compensation | 7,312 |  | 7,312 |
Net loss | (47,420) |  |  | (47,420)
Ending balance, value at Sep. 30, 2021 | $ (57,360) | $ 425 | $ 950,615 | $ (1,008,400)
Ending balance, shares at Sep. 30, 2021 | 424,879,000 | 424,879,000 |  |

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