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Business, basis of presentation, new accounting standards and summary of significant accounting policies - Additional Information (Details) | 3 Months Ended | 12 Months Ended
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Dec. 31, 2021 USD ($) | Sep. 30, 2021 USD ($) | [2] | Jun. 30, 2021 USD ($) | Mar. 31, 2021 USD ($) | Dec. 31, 2020 USD ($) | [3] | Sep. 30, 2020 USD ($) | [4] | Jun. 30, 2020 USD ($) | Mar. 31, 2020 USD ($) | Dec. 31, 2021 USD ($) Segment Location | Dec. 31, 2020 USD ($) | Dec. 31, 2019 USD ($)
Business Basis Of Presentation New Accounting Standards And Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Net loss | $ (42,960,000) | [1] | $ (47,420,000) | $ (42,652,000) | $ (39,383,000) | $ (42,087,000) | $ (32,612,000) | $ (51,976,000) | $ (56,849,000) | $ (172,415,000) | $ (183,524,000) | $ (176,145,000)
Current liabilities over current assets |  |  |  |  |  |  |  |  |  | 133,400,000 |  |
Total liabilities over total assets |  |  |  |  |  |  |  |  |  | 93,600,000 |  |
Cash FDIC insured amount | 250,000 |  |  |  |  |  |  |  |  | $ 250,000 |  |
License rights cost amortized expiration period |  |  |  |  |  |  |  |  |  | 2039-06 |  |
Number of reportable segment | Segment |  |  |  |  |  |  |  |  |  | 1 |  |
Number of operating segment | Segment |  |  |  |  |  |  |  |  |  | 1 |  |
Number of geographic location | Location |  |  |  |  |  |  |  |  |  | 1 |  |
Loss contingency accrual | 0 |  |  |  |  |  |  |  |  | $ 0 |  |
ANNOVERA [Member] |  |  |  |  |  |  |  |  |  |  |  |
Business Basis Of Presentation New Accounting Standards And Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Return period of unsalable prescription products |  |  |  |  |  |  |  |  |  | 12 months |  |
Vitamins, IMVEXXY and BIJUVA [Member] |  |  |  |  |  |  |  |  |  |  |  |
Business Basis Of Presentation New Accounting Standards And Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Shelf life of prescription products |  |  |  |  |  |  |  |  |  | 24 months |  |
BIJUVA and ANNOVERA [Member] |  |  |  |  |  |  |  |  |  |  |  |
Business Basis Of Presentation New Accounting Standards And Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Shelf life of prescription products |  |  |  |  |  |  |  |  |  | 18 months |  |
VitaCare [Member] | COVID-19 [Member] |  |  |  |  |  |  |  |  |  |  |  |
Business Basis Of Presentation New Accounting Standards And Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Cost savings initiative to reduce annual costs | 20,000,000.0 |  |  |  |  |  |  |  |  | $ 20,000,000.0 |  |
Minimum [Member] | Land and Building [Member] |  |  |  |  |  |  |  |  |  |  |  |
Business Basis Of Presentation New Accounting Standards And Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Useful life of assets |  |  |  |  |  |  |  |  |  | 3 years |  |
Minimum [Member] | Software and Software Development Costs [Member] |  |  |  |  |  |  |  |  |  |  |  |
Business Basis Of Presentation New Accounting Standards And Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Useful life of assets |  |  |  |  |  |  |  |  |  | 5 years |  |
Minimum [Member] | COVID-19 [Member] |  |  |  |  |  |  |  |  |  |  |  |
Business Basis Of Presentation New Accounting Standards And Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Cost savings initiative to reduce annual costs | $ 40,000,000.0 |  |  |  |  |  |  |  |  | $ 40,000,000.0 |  |
Maximum [Member] |  |  |  |  |  |  |  |  |  |  |  |
Business Basis Of Presentation New Accounting Standards And Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Return period of unsalable prescription products |  |  |  |  |  |  |  |  |  | 12 months |  |
Maximum [Member] | Land and Building [Member] |  |  |  |  |  |  |  |  |  |  |  |
Business Basis Of Presentation New Accounting Standards And Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Useful life of assets |  |  |  |  |  |  |  |  |  | 7 years |  |
Maximum [Member] | Software and Software Development Costs [Member] |  |  |  |  |  |  |  |  |  |  |  |
Business Basis Of Presentation New Accounting Standards And Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Useful life of assets |  |  |  |  |  |  |  |  |  | 7 years |  |
[1] | Included $5.1 million in senior executive severances, which included our former CEO.
[2] | Included $7.3 million in senior executive severances, which included our former EVP of Operations.
[3] | Included $0.5 million in write off of certain costs related to trademarks and patents.
[4] | Included (i) $2.0 million in license revenue related to the Knight License Agreement, (ii) $5.7 million in inventory charge, primarily related to BIJUVA, and (iii) $0.6 million in write off of certain costs related to trademarks and patents.

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