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Summary quarterly information (unaudited) | 12 Months Ended
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Dec. 31, 2021
Quarterly Financial Information Disclosure [Abstract] |
Summary quarterly information (unaudited) |
16. | Summary quarterly information (unaudited)
The following table sets forth a summary of the unaudited quarterly results for 2021 and 2020 (in thousands, except per share amounts):
|  | March 31, |  |  | June 30, |  |  | September 30, |  |  | December 31, |
|  | 2021 |  |  | 2021 |  |  | 2021 (2) |  |  | 2021 (3) |
Revenue, net |  | $ | 19,866 |  |  | $ | 23,001 |  |  | $ | 25,406 |  |  | $ | 18,678 |
Gross profit |  | $ | 15,179 |  |  | $ | 18,869 |  |  | $ | 20,124 |  |  | $ | 13,941 |
Loss from operations |  | $ | (29,278 | ) |  | $ | (35,179 | ) |  | $ | (39,921 | ) |  | $ | (35,392 | )
Net loss |  | $ | (39,383 | ) |  | $ | (42,652 | ) |  | $ | (47,420 | ) |  | $ | (42,960 | )
Loss per common share, basic and diluted (1) |  | $ | (0.11 | ) |  | $ | (0.11 | ) |  | $ | (0.11 | ) |  | $ | (0.10 | )
|  | March 31, |  |  | June 30, |  |  | September 30, |  |  | December 31, |
|  | 2020 |  |  | 2020 |  |  | 2020 (4) |  |  | 2020 (5) |
Revenue, net |  | $ | 12,251 |  |  | $ | 10,701 |  |  | $ | 19,342 |  |  | $ | 22,578 |
Gross profit |  | $ | 9,536 |  |  | $ | 6,301 |  |  | $ | 16,063 |  |  | $ | 16,997 |
Loss from operations |  | $ | (50,922 | ) |  | $ | (45,038 | ) |  | $ | (24,974 | ) |  | $ | (34,607 | )
Net loss |  | $ | (56,849 | ) |  | $ | (51,976 | ) |  | $ | (32,612 | ) |  | $ | (42,087 | )
Loss per common share, basic and diluted (1) |  | $ | (0.21 | ) |  | $ | (0.19 | ) |  | $ | (0.12 | ) |  | $ | (0.15 | )
| (1) | Basic and diluted loss per common share are computed independently for each quarter and the full year based upon respective weighted average shares outstanding. Therefore, the sum of the quarterly basic and diluted earnings per share amounts may not equal the annual basic and diluted earnings per share amounts reported.
| (2) | Included $7.3 million in senior executive severances, which included our former EVP of Operations.
| (3) | Included $5.1 million in senior executive severances, which included our former CEO.
| (4) | Included (i) $2.0 million in license revenue related to the Knight License Agreement, (ii) $5.7 million in inventory charge, primarily related to BIJUVA, and (iii) $0.6 million in write off of certain costs related to trademarks and patents.
| (5) | Included $0.5 million in write off of certain costs related to trademarks and patents.

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- Definition The entire disclosure for quarterly financial data. Includes, but is not limited to, tabular presentation of financial information for fiscal quarters, effect of year-end adjustments, and an explanation of matters or transactions that affect comparability of the information. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 270 -URI http://asc.fasb.org/topic&trid=2126967 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 270 -SubTopic 10 -Section 50 -Paragraph 1B -URI http://asc.fasb.org/extlink&oid=124502072&loc=SL124452896-108306 + Details
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