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Stockholders' Deficit - Schedule of Outstanding Awards Issued to Share-based Payment Award Plan and Inducement Grants (Details) - shares | Dec. 31, 2021 | Dec. 31, 2020 | Dec. 31, 2019 | Dec. 31, 2018
--- | --- | --- | --- | ---
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |
Options | 17,655,000 | 23,782,000 | 25,030,000 | 20,873,000
2019 Plan [Member] |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |
Number of shares common stock available | 13,054 |  |  |
2019 Plan [Member] | Options [Member] |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |
Options | 3,332 |  |  |
2019 Plan [Member] | Restricted Stock Units [Member] |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |
RSUs/PSUs | 10,174 |  |  |
2019 Plan [Member] | Performance Shares Unit [Member] |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |
RSUs/PSUs | 5,193 |  |  |
2012 Plan [Member] | Options [Member] |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |
Options | 4,601 |  |  |
2009 Plan [Member] | Options [Member] |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |
Options | 9,722 |  |  |
2021 Inducement Grants [Member] | Restricted Stock Units [Member] |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |
RSUs/PSUs | 3,410 |  |  |
2021 Inducement Grants [Member] | Performance Shares Unit [Member] |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |
RSUs/PSUs | 3,010 |  |  |

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- Definition Number of equity instruments other than options outstanding, including both vested and non-vested instruments. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1)(ii) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1)(i) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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