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LICENSE AGREEMENTS - Narrative (Details) € in Thousands |  |  |  | 1 Months Ended | 3 Months Ended | 12 Months Ended
--- | --- | --- | --- | --- | --- | ---
Aug. 05, 2021 USD ($) | Nov. 30, 2020 USD ($) | Jul. 30, 2020 USD ($) | Jan. 31, 2022 USD ($) | Dec. 31, 2021 USD ($) | Sep. 30, 2016 USD ($) | Aug. 31, 2016 USD ($) | Jun. 30, 2016 USD ($) period | Dec. 31, 2021 USD ($) | Jun. 30, 2021 USD ($) | Mar. 31, 2021 USD ($) | Mar. 31, 2021 EUR (€) | Dec. 31, 2020 USD ($) | Dec. 31, 2020 EUR (€) | Sep. 30, 2020 USD ($) | Dec. 31, 2021 USD ($) | Dec. 31, 2021 EUR (€) | Dec. 31, 2020 USD ($) | Dec. 31, 2019 USD ($)
Organization And Basis Of Presentation [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License and related revenue |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 26,544,000 |  | $ 11,236,000 | $ 0
License agreement, royalty rate |  |  |  |  | 2.00% |  |  |  | 2.00% |  |  |  |  |  |  | 2.00% |  |  |
Transaction price |  |  |  |  |  |  |  |  |  |  |  |  | $ 11,200,000 |  | $ 11,200,000 |  |  | 11,200,000 |
Qilu Pharmaceutical Co., Ltd. | Licensing Agreements |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Organization And Basis Of Presentation [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Potential milestone payments |  |  |  |  |  |  |  |  |  |  | $ 23,000,000 |  |  |  |  |  |  |  |
License and related revenue |  |  |  |  |  |  |  |  |  | $ 900,000 | 2,800,000 |  |  |  | $ 11,200,000 |  |  |  |
Upfront payment |  |  | $ 12,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 12,000,000 |
Total milestone payments |  |  | $ 23,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Royalty payment, percentage |  |  | 12.00% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Business combination, milestone payments |  |  |  |  |  |  |  |  |  |  | 3,000,000 |  |  |  |  |  |  |  |
University of Zurich |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Organization And Basis Of Presentation [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Royalty payment obligation, percent |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 4.00% | 4.00% |  |
Third party maximum ownership, percent |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 10.00% | 10.00% |  |
Third party minimum ownership, percent |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 2.00% | 2.00% |  |
Expenses related to achievement of development milestone |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 500,000 |  | 300,000 |
University of Zurich | Collaborative Arrangement, Revenue Based on Clinical Development Milestone |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Organization And Basis Of Presentation [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License agreement, amount payable upon achievement of specified milestone |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 500,000 |  |  |
Micromet AG |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Organization And Basis Of Presentation [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Royalty payment obligation, percent |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 3.50% | 3.50% |  |
Expenses related to achievement of development milestone |  |  |  |  |  |  |  |  |  |  | 600,000 | € 500 | 900,000 | € 700 |  |  |  |  |
Potential milestone payments |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 2,700,000 | € 2,400 |  |
License agreement, royalty payment, reduction, conditions not met |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 1.50% | 1.50% |  |
License maintenance fees |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 56,625 | € 50 |  |
XOMA Ireland Limited |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Organization And Basis Of Presentation [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License agreement, amount payable upon achievement of specified milestone |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 250,000 |  |  |
Royalty payment obligation, percent |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 2.50% | 2.50% |  |
Third party maximum ownership, percent |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 50.00% | 50.00% |  |
Third party minimum ownership, percent |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 1.75% | 1.75% |  |
Roche |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Organization And Basis Of Presentation [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License agreement, up-front fee |  |  |  |  |  |  | $ 7,500,000 |  |  |  |  |  |  |  |  |  |  |  |
License agreement, additional up-front fee |  |  |  |  |  |  | 262,500,000 |  |  |  |  |  |  |  |  |  |  |  |
Milestone achieved |  |  |  |  | $ 20,000,000 |  |  |  | $ 20,000,000 |  |  |  |  |  |  | $ 20,000,000 |  |  |
Payment terms |  |  |  |  | 30 days |  |  |  |  |  |  |  |  |  |  |  |  |  |
License agreement, option periods | period |  |  |  |  |  |  |  | 2 |  |  |  |  |  |  |  |  |  |  |
License agreement, buyout amount under first option period |  |  |  |  |  |  |  | $ 135,000,000 |  |  |  |  |  |  |  |  |  |  |
License agreement, period to pay buyout option once exercised |  |  |  |  |  |  |  | 30 days |  |  |  |  |  |  |  |  |  |  |
License agreement, buyout amount under second option period |  |  |  |  |  |  |  | $ 265,000,000 |  |  |  |  |  |  |  |  |  |  |
Buyout amount under second option period |  |  |  |  |  |  |  | $ 220,000,000 |  |  |  |  |  |  |  |  |  |  |
Roche | Subsequent Event |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Organization And Basis Of Presentation [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Proceeds from milestone achieved |  |  |  | $ 20,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Roche | EBI-031 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Organization And Basis Of Presentation [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Milestone achieved |  |  |  |  | $ 20,000,000 |  |  |  | 20,000,000 |  |  |  |  |  |  | $ 20,000,000 |  |  |
Payment terms |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 30 days | 30 days |  |
License and related revenue |  |  |  |  |  |  |  |  | $ 20,000,000 |  |  |  |  |  |  |  |  |  |
Roche | EBI-031 | Minimum |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Organization And Basis Of Presentation [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License agreement, royalty rate |  |  |  |  | 7.50% |  |  |  | 7.50% |  |  |  |  |  |  | 7.50% |  |  |
Roche | EBI-031 | Maximum |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Organization And Basis Of Presentation [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License agreement, royalty rate |  |  |  |  | 15.00% |  |  |  | 15.00% |  |  |  |  |  |  | 15.00% |  |  |
Roche | EBI-031 | Subsequent Event |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Organization And Basis Of Presentation [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Proceeds from milestone achieved |  |  |  | $ 20,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Roche | IL-6 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Organization And Basis Of Presentation [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License agreement, royalty rate |  |  |  |  | 50.00% |  |  |  | 50.00% |  |  |  |  |  |  | 50.00% |  |  |
Roche | First Indication |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Organization And Basis Of Presentation [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License agreement, amount payable upon achievement of specified milestone |  |  |  |  |  |  | 197,500,000 |  |  |  |  |  |  |  |  |  |  |  |
Roche | Collaborative arrangement, revenue based on development milestone |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Organization And Basis Of Presentation [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License agreement, amount payable upon achievement of specified milestone |  |  |  |  |  |  | 72,500,000 |  |  |  |  |  |  |  |  |  |  |  |
Roche | Collaborative arrangement, revenue based on development milestone | EBI-031 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Organization And Basis Of Presentation [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License agreement, amount payable upon achievement of specified milestone |  |  |  |  |  | $ 22,500,000 |  |  |  |  |  |  |  |  |  |  |  |  |
Roche | Collaborative Arrangement, Revenue Based on Development Milestone, Phase II |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Organization And Basis Of Presentation [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License agreement, amount payable upon achievement of specified milestone |  |  |  |  |  |  | 30,000,000 |  |  |  |  |  |  |  |  |  |  |  |
Roche | Collaborative arrangement, revenue based on regulatory milestone |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Organization And Basis Of Presentation [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License agreement, amount payable upon achievement of specified milestone |  |  |  |  |  |  | 50,000,000 |  |  |  |  |  |  |  |  |  |  |  |
Roche | Collaborative arrangement, revenue based on commercialization milestone |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Organization And Basis Of Presentation [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License agreement, amount payable upon achievement of specified milestone |  |  |  |  |  |  | $ 75,000,000 |  |  |  |  |  |  |  |  |  |  |  |
Roche | Second Indication |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Organization And Basis Of Presentation [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License agreement, amount payable upon achievement of specified milestone |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 65,000,000 |  |  |
MENA License Agreement | Licensing Agreements |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Organization And Basis Of Presentation [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License and related revenue |  |  |  |  |  |  |  |  |  |  | $ 1,500,000 |  |  |  |  |  |  |  |
Upfront payment |  | $ 3,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Transaction price |  |  |  |  | $ 1,500,000 |  |  |  | $ 1,500,000 |  |  |  | $ 1,500,000 |  |  | $ 1,500,000 |  | $ 1,500,000 |
Royalty revenue, percentage |  |  |  |  |  |  |  |  |  |  |  |  | 0.50 |  |  |  |  | 0.50 |
Eczacibasi Pharmaceuticals Marketing Agreement |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Organization And Basis Of Presentation [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Potential milestone payments | $ 2,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Transaction price | $ 1,500,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Eczacibasi Pharmaceuticals Marketing Agreement | TURKEY |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Organization And Basis Of Presentation [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Royalty revenue, percentage | 0.30 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

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