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SHARE-BASED COMPENSATION (Tables)
3 Months Ended
Mar. 31, 2022
Share-based Payment Arrangement [Abstract]  
Schedule of Share-Based Compensation Expense
The following table sets forth the amount of share-based compensation expense recognized by the Company by line item on its Condensed Consolidated Statements of Operations and Comprehensive Loss for three months ended March 31, 2022 and 2021 (in thousands):
Three Months Ended March 31,
20222021
Research and development$502 $178 
General and administrative1,392 780 
Total Share Based Compensation $1,894 $958 
Schedule of Stock Option Activity The following table sets forth a summary of the Company’s total stock option activity, including awards granted under the 2014 Plan and 2009 Plan and inducement grants made outside of stockholder approved plans, for the three months ended March 31, 2022:
Number of Shares under Option
(in thousands)
Weighted-Average
Exercise Price
Weighted-Average Remaining
Contractual 
Life
(in years)
Aggregate
Intrinsic
Value
(in thousands)
Outstanding at December 31, 202115,703 $1.938.03$82 
Granted1,080 $0.71
Exercised— 
Canceled or forfeited— 
Outstanding at March 31, 202216,783 $1.857.92$
Exercisable at March 31, 20228,513 $1.687.26$
Schedule of Weighted-Average Inputs and Assumptions in Black-Scholes Option
For the three months ended March 31, 2022 and 2021, the grant-date fair value of stock options was determined using the following weighted-average inputs and assumptions in the Black-Scholes option pricing model:
Three Months Ended March 31,
20222021
Fair market value$0.71$3.15
Grant exercise price$0.71$3.15
Expected term (in years)6.06.0
Risk-free interest rate1.7%0.8%
Expected volatility71.9%75.0%
Dividend yield—%—%
Schedule of the Status of Restricted Stock Units
The following table sets forth a summary of the Company's RSU and PSU activity for the three months ended March 31, 2022:
Restricted Stock Units
(in thousands)
Weighted Average Grant Date Fair Value
Unvested at December 31, 20213,041 $0.80
Granted RSU3,960 $0.67
Granted PSU1,004 $0.67
Unvested at March 31, 2022
8,005 $0.72