    <SEC-DOCUMENT>0001485003-22-000154-index.html : 20221107
    <SEC-HEADER>0001485003-22-000154.hdr.sgml : 20221107
    <ACCEPTANCE-DATETIME>20221107080030
    ACCESSION NUMBER:		0001485003-22-000154
    CONFORMED SUBMISSION TYPE:	8-K
    PUBLIC DOCUMENT COUNT:		10
    CONFORMED PERIOD OF REPORT:	20221107
    ITEM INFORMATION:		Results of Operations and Financial Condition
    ITEM INFORMATION:		Financial Statements and Exhibits
    FILED AS OF DATE:		20221107
    DATE AS OF CHANGE:		20221107

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Sesen Bio, Inc.
    		CENTRAL INDEX KEY:			0001485003
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		IRS NUMBER:				262025616
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		8-K
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-36296
    		FILM NUMBER:		221363775

    	BUSINESS ADDRESS:
    		STREET 1:		245 FIRST STREET
    		STREET 2:		SUITE 1800
    		CITY:			CAMBRIDGE
    		STATE:			MA
    		ZIP:			02142
    		BUSINESS PHONE:		617-444-8550

    	MAIL ADDRESS:
    		STREET 1:		245 FIRST STREET
    		STREET 2:		SUITE 1800
    		CITY:			CAMBRIDGE
    		STATE:			MA
    		ZIP:			02142

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	Eleven Biotherapeutics, Inc.
    		DATE OF NAME CHANGE:	20100223
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>8-K
    <SEQUENCE>1
    <FILENAME>sesnform3q2022earningsrele.htm
    <DESCRIPTION>8-K
    <TEXT>
    Document 1 - file: sesnform3q2022earningsrele.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-99.1
    <SEQUENCE>2
    <FILENAME>ex991_3q2022earningsrele.htm
    <DESCRIPTION>EX-99.1
    <TEXT>
    Document 2 - file: ex991_3q2022earningsrele.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>ex991_3q2022earningsrele001.jpg
    <TEXT>
    Document 3 - file: ex991_3q2022earningsrele001.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>ex991_3q2022earningsrele002.jpg
    <TEXT>
    Document 4 - file: ex991_3q2022earningsrele002.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>5
    <FILENAME>ex991_3q2022earningsrele003.jpg
    <TEXT>
    Document 5 - file: ex991_3q2022earningsrele003.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>6
    <FILENAME>ex991_3q2022earningsrele004.jpg
    <TEXT>
    Document 6 - file: ex991_3q2022earningsrele004.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>7
    <FILENAME>ex991_3q2022earningsrele005.jpg
    <TEXT>
    Document 7 - file: ex991_3q2022earningsrele005.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>8
    <FILENAME>ex991_3q2022earningsrele006.jpg
    <TEXT>
    Document 8 - file: ex991_3q2022earningsrele006.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>9
    <FILENAME>ex991_3q2022earningsrele007.jpg
    <TEXT>
    Document 9 - file: ex991_3q2022earningsrele007.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>10
    <FILENAME>ex991_3q2022earningsrele008.jpg
    <TEXT>
    Document 10 - file: ex991_3q2022earningsrele008.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>