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Related-Party Transactions (Details) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2023
Jun. 30, 2022
Jun. 30, 2023
Jun. 30, 2022
Related-Party Transactions        
Research and development $ 18,518 $ 14,212 $ 35,159 $ 22,979
Collaboration revenues 3,560 2,703 6,803 3,525
Penn        
Related-Party Transactions        
Research and development $ 0 $ 200 $ 300 $ 400