<SEC-DOCUMENT>0001068238-23-000067.txt : 20230322
<SEC-HEADER>0001068238-23-000067.hdr.sgml : 20230322
<ACCEPTANCE-DATETIME>20230322111345
ACCESSION NUMBER:		0001068238-23-000067
CONFORMED SUBMISSION TYPE:	SC 13D/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20230322
DATE AS OF CHANGE:		20230322

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Carisma Therapeutics Inc.
		CENTRAL INDEX KEY:			0001485003
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				262025616
		STATE OF INCORPORATION:			PA
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13D/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-87951
		FILM NUMBER:		23751853

	BUSINESS ADDRESS:	
		STREET 1:		3675 MARKET STREET
		STREET 2:		SUITE 200
		CITY:			PHILADELPHIA
		STATE:			PA
		ZIP:			19104
		BUSINESS PHONE:		2674916422

	MAIL ADDRESS:	
		STREET 1:		3675 MARKET STREET
		STREET 2:		SUITE 200
		CITY:			PHILADELPHIA
		STATE:			PA
		ZIP:			19104

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Sesen Bio, Inc.
		DATE OF NAME CHANGE:	20180516

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Eleven Biotherapeutics, Inc.
		DATE OF NAME CHANGE:	20100223

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			HealthCap VII, L.P.
		CENTRAL INDEX KEY:			0001645161
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13D/A

	BUSINESS ADDRESS:	
		STREET 1:		18 AVENUE D'OUCHY
		CITY:			CH 1006 LAUSANNE
		STATE:			V8
		ZIP:			1000-1018
		BUSINESS PHONE:		41 21 614 3500

	MAIL ADDRESS:	
		STREET 1:		18 AVENUE D'OUCHY
		CITY:			CH 1006 LAUSANNE
		STATE:			V8
		ZIP:			1000-1018
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13D/A
<SEQUENCE>1
<FILENAME>carisma_sch_13da.htm
<DESCRIPTION>CARISMA SCHEDULE 13D/A
<TEXT>
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        <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-weight: bold;">UNITED STATES<br>
          SECURITIES AND EXCHANGE COMMISSION</div>
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      <div style="text-align: center; margin-bottom: 12pt; font-family: 'Times New Roman',Times,serif; font-weight: bold;">Washington, D.C. 20549</div>
      <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-weight: bold;">Schedule&#160;13D/A</div>
      <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-weight: bold;">Under the Securities Exchange Act of 1934</div>
      <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-weight: bold;">(Amendment No. 1)*</div>
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        <div style="margin-bottom: 6pt;"><br>
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        <div style="text-align: center;">_______________________<br>
        </div>
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      <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-weight: bold;">CARISMA THERAPEUTICS INC.</div>
      <div style="text-align: center; margin-bottom: 12pt; font-family: 'Times New Roman',Times,serif;">(Name of Issuer)</div>
      <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-weight: bold;">Common Stock, par value $0.001 per share</div>
      <div style="text-align: center; margin-bottom: 12pt; font-family: 'Times New Roman',Times,serif;">(Title of Class&#160;of Securities)</div>
      <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-weight: bold;">14216R 101</div>
      <div style="text-align: center; margin-bottom: 12pt; font-family: 'Times New Roman',Times,serif;">(CUSIP Number)</div>
      <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-weight: bold;">HealthCap VII, L.P.</div>
      <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-weight: bold;">Represented by its general partner</div>
      <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-weight: bold;">HealthCap VII GP S.A.</div>
      <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-weight: bold;">23 Avenue Villamont</div>
      <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-weight: bold;">Lausanne, V8 CH -1005</div>
      <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-weight: bold;">+4121 614 3500</div>
      <div style="text-align: center; font-family: 'Times New Roman',Times,serif;">(Name, Address and Telephone Number of Person</div>
      <div style="text-align: center; margin-bottom: 12pt; font-family: 'Times New Roman',Times,serif;">Authorized to Receive Notices and Communications)</div>
      <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-weight: bold;">March 22, 2023</div>
      <div style="text-align: center; font-family: 'Times New Roman',Times,serif;">(Date of Event which Requires Filing of this Statement)</div>
      <div>
        <div style="margin-bottom: 12pt; text-align: center;">__________________________<br>
        </div>
        <div><br>
        </div>
      </div>
      <div style="text-align: justify; margin-bottom: 12pt; font-family: 'Times New Roman',Times,serif;">If the filing person has previously filed a statement on Schedule&#160;13G to report the acquisition that is the subject of this Schedule&#160;13D, and is filing
        this schedule because of &#167;240.13d-1(e), &#167;240.13d&#8209;1(f) or &#167;240.13d-1(g), check the following box: &#9633;</div>
      <div style="text-align: justify; margin-bottom: 12pt; font-family: 'Times New Roman',Times,serif;">* The remainder of this cover page shall be filled out for a reporting person&#8217;s initial filing on this form with respect to the subject class of
        securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page.</div>
      <div style="text-align: justify; margin-bottom: 12pt; font-family: 'Times New Roman',Times,serif;">The information required on the remainder of this cover page&#160;shall not be deemed to be &#8220;filed&#8221; for the purpose of Section&#160;18 of the Securities Exchange
        Act of 1934, as amended (&#8220;<font style="font-weight: bold;">Act</font>&#8221;) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).</div>
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        <div style="text-align: right; font-family: 'Times New Roman',Times,serif; font-size: 12pt; font-weight: bold;"> <font style="font-weight: normal; font-size: 10pt;">Page 2 of 6</font><font style="font-size: 10pt;"><br>
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        <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-weight: bold;">SCHEDULE&#160;13D</div>
      </div>
      <div style="text-align: justify; margin-bottom: 12pt; font-family: 'Times New Roman',Times,serif;">CUSIP No. 14216R 101</div>
      <br>
      <table cellspacing="0" cellpadding="0" border="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" id="ze4fc3dbf2f01406c96d0bd507c125e5d">

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            <td style="border-left: 1px solid #000000; border-right: 1px solid #000000; border-top: 1px solid; vertical-align: top; width: 10%;">
              <div style="margin-left: 6.5pt;">1.&#160;</div>
            </td>
            <td colspan="4" style="vertical-align: top; border-right: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0);">
              <div style="text-align: justify;">Name of Reporting Person</div>
            </td>
          </tr>
          <tr>
            <td style="border-bottom: 1px solid; border-left: 1px solid #000000; border-right: 1px solid #000000; vertical-align: top; width: 10%;">&#160;</td>
            <td colspan="4" style="vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0);">
              <div style="text-align: justify;">HealthCap VII, L.P.</div>
            </td>
          </tr>
          <tr>
            <td style="border-left: 1px solid #000000; border-right: 1px solid #000000; vertical-align: top; width: 10%;">
              <div style="margin-left: 6.5pt;">2.</div>
            </td>
            <td colspan="4" style="vertical-align: top; border-right: 1px solid rgb(0, 0, 0);">
              <div style="text-align: justify;">Check the Appropriate Box if a Member of a Group</div>
            </td>
          </tr>
          <tr>
            <td style="border-bottom: 1px solid; border-left: 1px solid #000000; border-right: 1px solid #000000; vertical-align: top; width: 10%;">&#160;</td>
            <td colspan="2" style="vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="text-align: justify;">(a)<font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 36pt" id="TRGRRTFtoHTMLTab"> </font>&#9744;</div>
            </td>
            <td colspan="2" style="vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0);">
              <div style="text-align: justify;">(b)<font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 36pt" id="TRGRRTFtoHTMLTab"> </font>&#9744;</div>
            </td>
          </tr>
          <tr>
            <td style="border-bottom: 1px solid; border-left: 1px solid #000000; border-right: 1px solid #000000; vertical-align: top; width: 10%;">
              <div style="margin-left: 6.5pt;">3.</div>
            </td>
            <td colspan="4" style="vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0);">
              <div style="text-align: justify;">SEC Use Only</div>
            </td>
          </tr>
          <tr>
            <td style="border-left: 1px solid #000000; border-right: 1px solid #000000; vertical-align: top; width: 10%;">
              <div style="margin-left: 6.5pt;">4.</div>
            </td>
            <td colspan="4" style="vertical-align: top; border-right: 1px solid rgb(0, 0, 0);">
              <div style="text-align: justify;">Source of Funds (See Instructions)</div>
            </td>
          </tr>
          <tr>
            <td style="border-bottom: 1px solid; border-left: 1px solid #000000; border-right: 1px solid #000000; vertical-align: top; width: 10%;">&#160;</td>
            <td colspan="4" style="vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0);">
              <div style="text-align: justify;">WC</div>
            </td>
          </tr>
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            <td style="border-left: 1px solid #000000; border-right: 1px solid #000000; vertical-align: top; width: 10%;">
              <div style="margin-left: 6.5pt;">5.</div>
            </td>
            <td colspan="3" style="vertical-align: top;">
              <div style="text-align: justify;">Check if Disclosure of Legal Proceedings Is Required Pursuant to Items&#160;2(d) or 2(e)</div>
            </td>
            <td style="width: 11.88%; vertical-align: bottom; border-right: 1px solid rgb(0, 0, 0);">
              <div>&#9744;</div>
            </td>
          </tr>
          <tr>
            <td style="border-bottom: 1px solid; border-left: 1px solid #000000; border-right: 1px solid #000000; vertical-align: top; width: 10%;">&#160;</td>
            <td colspan="4" style="vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0);">
              <div style="text-align: justify;">Not Applicable</div>
            </td>
          </tr>
          <tr>
            <td style="border-left: 1px solid #000000; border-right: 1px solid #000000; vertical-align: top; width: 10%;">
              <div style="margin-left: 6.5pt;">6.</div>
            </td>
            <td colspan="4" style="vertical-align: top; border-right: 1px solid rgb(0, 0, 0);">
              <div style="text-align: justify;">Citizenship or Place of Organization</div>
            </td>
          </tr>
          <tr>
            <td style="border-bottom: 1px solid; border-left: 1px solid #000000; border-right: 1px solid #000000; vertical-align: top; width: 10%;">&#160;</td>
            <td colspan="4" style="vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0);">
              <div style="text-align: justify;">Delaware</div>
            </td>
          </tr>
          <tr>
            <td rowspan="8" style="border-bottom: 1px solid #000000; border-left: 1px solid #000000; border-right: 1px solid #000000; vertical-align: middle; width: 10%;">
              <div style="text-align: center;">Number of Shares Beneficially Owned by Each Reporting Person With</div>
            </td>
            <td style="border-right: 1px solid #000000; vertical-align: top; width: 10%;">
              <div>&#160; 7.</div>
            </td>
            <td colspan="3" style="vertical-align: top; border-right: 1px solid rgb(0, 0, 0);">
              <div style="text-align: justify;">Sole Voting Power</div>
            </td>
          </tr>
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            <td style="border-bottom: 1px solid; border-right: 1px solid #000000; vertical-align: top; width: 10%;">&#160;</td>
            <td colspan="3" style="vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0);">
              <div style="text-align: justify;">0</div>
            </td>
          </tr>
          <tr>
            <td style="border-right: 1px solid #000000; vertical-align: top; width: 10%;">
              <div style="text-align: justify;">&#160; 8.</div>
            </td>
            <td colspan="3" style="vertical-align: top; border-right: 1px solid rgb(0, 0, 0);">
              <div style="text-align: justify;">Shared Voting Power</div>
            </td>
          </tr>
          <tr>
            <td style="border-bottom: 1px solid; border-right: 1px solid #000000; vertical-align: top; width: 10%;">&#160;</td>
            <td colspan="3" style="vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0);">
              <div style="text-align: justify;">3,398,248(1)</div>
            </td>
          </tr>
          <tr>
            <td style="border-right: 1px solid #000000; vertical-align: top; width: 10%;">
              <div style="text-align: justify;">&#160; 9.</div>
            </td>
            <td colspan="3" style="vertical-align: top; border-right: 1px solid rgb(0, 0, 0);">
              <div style="text-align: justify;">Sole Dispositive Power</div>
            </td>
          </tr>
          <tr>
            <td style="border-bottom: 1px solid; border-right: 1px solid #000000; vertical-align: top; width: 10%;">&#160;</td>
            <td colspan="3" style="vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0);">
              <div style="text-align: justify;">0</div>
            </td>
          </tr>
          <tr>
            <td style="border-right: 1px solid #000000; vertical-align: top; width: 10%;">
              <div style="text-align: justify;">&#160; 10.</div>
            </td>
            <td colspan="3" style="vertical-align: top; border-right: 1px solid rgb(0, 0, 0);">
              <div style="text-align: justify;">Shared Dispositive Power</div>
            </td>
          </tr>
          <tr>
            <td style="border-bottom: 1px solid; border-right: 1px solid #000000; vertical-align: top; width: 10%;">&#160;</td>
            <td colspan="3" style="vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0);">
              <div style="text-align: justify;">3,398,248(1)</div>
            </td>
          </tr>
          <tr>
            <td style="border-left: 1px solid #000000; border-right: 1px solid #000000; vertical-align: top; width: 10%;">
              <div>&#160; 11.</div>
            </td>
            <td colspan="4" style="vertical-align: top; border-right: 1px solid rgb(0, 0, 0);">
              <div style="text-align: justify;">Aggregate Amount Beneficially Owned by Each Reporting Person</div>
            </td>
          </tr>
          <tr>
            <td style="border-bottom: 1px solid; border-left: 1px solid #000000; border-right: 1px solid #000000; vertical-align: top; width: 10%;">&#160;</td>
            <td colspan="4" style="vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0);">
              <div style="text-align: justify;">3,398,248(1)</div>
            </td>
          </tr>
          <tr>
            <td style="border-bottom: 1px solid; border-left: 1px solid #000000; border-right: 1px solid #000000; vertical-align: top; width: 10%;">
              <div>&#160; 12.</div>
            </td>
            <td colspan="3" style="vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="text-align: justify;">Check if the Aggregate Amount in Row&#160;(11) Excludes Certain Shares</div>
            </td>
            <td style="width: 11.88%; vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0);">
              <div style="text-align: justify;">&#9744;</div>
            </td>
          </tr>
          <tr>
            <td style="border-left: 1px solid #000000; border-right: 1px solid #000000; vertical-align: top; width: 10%;">
              <div>&#160; 13.</div>
            </td>
            <td colspan="4" style="vertical-align: top; border-right: 1px solid rgb(0, 0, 0);">
              <div style="text-align: justify;">Percent of Class&#160;Represented by Amount in Row&#160;(11)</div>
            </td>
          </tr>
          <tr>
            <td style="border-bottom: 1px solid; border-left: 1px solid #000000; border-right: 1px solid #000000; vertical-align: top; width: 10%;">&#160;</td>
            <td colspan="4" style="vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0);">
              <div style="text-align: justify;">8.4%(2)</div>
            </td>
          </tr>
          <tr>
            <td style="border-left: 1px solid #000000; border-right: 1px solid #000000; vertical-align: top; width: 10%;">
              <div>&#160; 14.</div>
            </td>
            <td colspan="4" style="vertical-align: top; border-right: 1px solid rgb(0, 0, 0);">
              <div style="text-align: justify;">Type of Reporting Person</div>
            </td>
          </tr>
          <tr>
            <td style="border-bottom: 1px solid; border-left: 1px solid #000000; border-right: 1px solid #000000; vertical-align: top; width: 10%;">&#160;</td>
            <td colspan="4" style="vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0);">
              <div style="text-align: justify;">PN</div>
            </td>
          </tr>

      </table>
      <div style="text-align: justify; text-indent: -18pt; margin-left: 18pt; margin-bottom: 12pt; font-family: 'Times New Roman',Times,serif;"> </div>
      <div style="text-align: justify; text-indent: -18pt; margin-left: 18pt; margin-bottom: 12pt; font-family: 'Times New Roman',Times,serif;">(1) The number of shares of CARISMA Therapeutics Inc. (the &#8220;<font style="font-weight: bold;">Issuer</font>&#8221;)
        reported is based on the Issuer&#8217;s Registration Statement on Form S-4 filed with the Securities and Exchange Commission (&#8220;<font style="font-weight: bold;">SEC</font>&#8221;) on October 14, 2022, as amended by the Prospectus Supplement filed with the SEC
        on February 16, 2023, and giving effect, in connection with the Merger, to the final exchange ratio of 37.9881 provided by the Issuer and the 1-for-20 reverse stock split effective at 5:01 p.m. Eastern Time on March 7, 2023, as reported on the
        Issuer&#8217;s Current Report on Form 8-K filed with the SEC on March 8, 2023.&#160; The number of shares has been amended in this Amendment No. 1 to Schedule 13D to reflect the final exchange ratio, which was not known when the Schedule 13D was originally
        filed. For the avoidance of doubt, no disposition of shares of the Issuer have been made by the reporting person, and this Amendment No. 1 to Schedule 13D is being filed solely to reflect such final exchange ratio.<br>
      </div>
      <div style="text-align: justify; text-indent: -18pt; margin-left: 18pt; margin-bottom: 12pt; font-family: 'Times New Roman',Times,serif;">(2) As more fully described in Item 5 of this Amendment No. 1 to Schedule 13D, based on 40,254,666 shares of
        Common Stock of the Issuer (the &#8220;<font style="font-weight: bold;">Common Stock</font>&#8221;) outstanding as of March 19, 2023, the Reporting Person may be deemed to have beneficial ownership of 3,398,248 shares of Common Stock, which is equal to
        approximately 8.4% of the voting power of issued and outstanding Common Stock as of March 19, 2023.</div>
      <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" id="DSPFPageBreakArea">
        <div style="page-break-after:always;" id="DSPFPageBreak">
          <hr noshade="noshade" style="margin: 4px 0px; width: 100%; border-width: 0; height: 2px; color: #000000; background-color: #000000; clear: both;"></div>
      </div>
      <div>
        <div style="text-align: right; font-family: 'Times New Roman',Times,serif; font-size: 12pt; font-weight: bold;"> <font style="font-weight: normal; font-size: 10pt;">Page 3 of 6</font><font style="font-size: 10pt;"><br>
          </font></div>
        <div style="text-align: center; font-family: 'Times New Roman',Times,serif; font-weight: bold;">SCHEDULE&#160;13D</div>
      </div>
      <div style="text-align: justify; margin-bottom: 12pt; font-family: 'Times New Roman',Times,serif;">CUSIP No. 14216R 101</div>
      <div style="text-align: justify; margin-bottom: 12pt; font-family: 'Times New Roman',Times,serif;">
        <table cellspacing="0" cellpadding="0" border="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" id="z3a1eac718d9a49cdbc49305e4a0a97df">

            <tr>
              <td style="border-left: 1px solid #000000; border-right: 1px solid #000000; border-top: 1px solid; vertical-align: top; width: 10%;">
                <div style="margin-left: 6.5pt;">1.&#160;</div>
              </td>
              <td colspan="4" style="vertical-align: top; border-right: 1px solid rgb(0, 0, 0); border-top: 1px solid rgb(0, 0, 0);">
                <div style="text-align: justify;">Name of Reporting Person</div>
              </td>
            </tr>
            <tr>
              <td style="border-bottom: 1px solid; border-left: 1px solid #000000; border-right: 1px solid #000000; vertical-align: top; width: 10%;">&#160;</td>
              <td colspan="4" style="vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0);">
                <div style="text-align: justify;">HealthCap VII GP S.A.</div>
              </td>
            </tr>
            <tr>
              <td style="border-left: 1px solid #000000; border-right: 1px solid #000000; vertical-align: top; width: 10%;">
                <div style="margin-left: 6.5pt;">2.</div>
              </td>
              <td colspan="4" style="vertical-align: top; border-right: 1px solid rgb(0, 0, 0);">
                <div style="text-align: justify;">Check the Appropriate Box if a Member of a Group</div>
              </td>
            </tr>
            <tr>
              <td style="border-bottom: 1px solid; border-left: 1px solid #000000; border-right: 1px solid #000000; vertical-align: top; width: 10%;">&#160;</td>
              <td colspan="2" style="vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0);">
                <div style="text-align: justify;">(a)<font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 36pt" id="TRGRRTFtoHTMLTab"> </font>&#9744;</div>
              </td>
              <td colspan="2" style="vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0);">
                <div style="text-align: justify;">(b)<font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 36pt" id="TRGRRTFtoHTMLTab"> </font>&#9744;</div>
              </td>
            </tr>
            <tr>
              <td style="border-bottom: 1px solid; border-left: 1px solid #000000; border-right: 1px solid #000000; vertical-align: top; width: 10%;">
                <div style="margin-left: 6.5pt;">3.</div>
              </td>
              <td colspan="4" style="vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0);">
                <div style="text-align: justify;">SEC Use Only</div>
              </td>
            </tr>
            <tr>
              <td style="border-left: 1px solid #000000; border-right: 1px solid #000000; vertical-align: top; width: 10%;">
                <div style="margin-left: 6.5pt;">4.</div>
              </td>
              <td colspan="4" style="vertical-align: top; border-right: 1px solid rgb(0, 0, 0);">
                <div style="text-align: justify;">Source of Funds (See Instructions)</div>
              </td>
            </tr>
            <tr>
              <td style="border-bottom: 1px solid; border-left: 1px solid #000000; border-right: 1px solid #000000; vertical-align: top; width: 10%;">&#160;</td>
              <td colspan="4" style="vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0);">
                <div style="text-align: justify;">AF</div>
              </td>
            </tr>
            <tr>
              <td style="border-left: 1px solid #000000; border-right: 1px solid #000000; vertical-align: top; width: 10%;">
                <div style="margin-left: 6.5pt;">5.</div>
              </td>
              <td colspan="3" style="vertical-align: top;">
                <div style="text-align: justify;">Check if Disclosure of Legal Proceedings Is Required Pursuant to Items&#160;2(d) or 2(e)</div>
              </td>
              <td style="width: 9.28%; vertical-align: bottom; border-right: 1px solid rgb(0, 0, 0);">
                <div>&#9744;</div>
              </td>
            </tr>
            <tr>
              <td style="border-bottom: 1px solid; border-left: 1px solid #000000; border-right: 1px solid #000000; vertical-align: top; width: 10%;">&#160;</td>
              <td colspan="4" style="vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0);">
                <div style="text-align: justify;">Not Applicable</div>
              </td>
            </tr>
            <tr>
              <td style="border-left: 1px solid #000000; border-right: 1px solid #000000; vertical-align: top; width: 10%;">
                <div style="margin-left: 6.5pt;">6.</div>
              </td>
              <td colspan="4" style="vertical-align: top; border-right: 1px solid rgb(0, 0, 0);">
                <div style="text-align: justify;">Citizenship or Place of Organization</div>
              </td>
            </tr>
            <tr>
              <td style="border-bottom: 1px solid; border-left: 1px solid #000000; border-right: 1px solid #000000; vertical-align: top; width: 10%;">&#160;</td>
              <td colspan="4" style="vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0);">
                <div style="text-align: justify;">Switzerland</div>
              </td>
            </tr>
            <tr>
              <td rowspan="8" style="border-bottom: 1px solid #000000; border-left: 1px solid #000000; border-right: 1px solid #000000; vertical-align: middle; width: 10%;">
                <div style="text-align: center;">Number of Shares Beneficially Owned by Each Reporting Person With</div>
              </td>
              <td style="border-right: 1px solid #000000; vertical-align: top; width: 10%;">
                <div>&#160; 7.</div>
              </td>
              <td colspan="3" style="vertical-align: top; border-right: 1px solid rgb(0, 0, 0);">
                <div style="text-align: justify;">Sole Voting Power</div>
              </td>
            </tr>
            <tr>
              <td style="border-bottom: 1px solid; border-right: 1px solid #000000; vertical-align: top; width: 10%;">&#160;</td>
              <td colspan="3" style="vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0);">
                <div style="text-align: justify;">0</div>
              </td>
            </tr>
            <tr>
              <td style="border-right: 1px solid #000000; vertical-align: top; width: 10%;">
                <div style="text-align: justify;">&#160; 8.</div>
              </td>
              <td colspan="3" style="vertical-align: top; border-right: 1px solid rgb(0, 0, 0);">
                <div style="text-align: justify;">Shared Voting Power</div>
              </td>
            </tr>
            <tr>
              <td style="border-bottom: 1px solid; border-right: 1px solid #000000; vertical-align: top; width: 10%;">&#160;</td>
              <td colspan="3" style="vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0);">
                <div style="text-align: justify;">3,398,248(1)(2)</div>
              </td>
            </tr>
            <tr>
              <td style="border-right: 1px solid #000000; vertical-align: top; width: 10%;">
                <div style="text-align: justify;">&#160; 9.</div>
              </td>
              <td colspan="3" style="vertical-align: top; border-right: 1px solid rgb(0, 0, 0);">
                <div style="text-align: justify;">Sole Dispositive Power</div>
              </td>
            </tr>
            <tr>
              <td style="border-bottom: 1px solid; border-right: 1px solid #000000; vertical-align: top; width: 10%;">&#160;</td>
              <td colspan="3" style="vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0);">
                <div style="text-align: justify;">0</div>
              </td>
            </tr>
            <tr>
              <td style="border-right: 1px solid #000000; vertical-align: top; width: 10%;">
                <div style="text-align: justify;">&#160; 10.</div>
              </td>
              <td colspan="3" style="vertical-align: top; border-right: 1px solid rgb(0, 0, 0);">
                <div style="text-align: justify;">Shared Dispositive Power</div>
              </td>
            </tr>
            <tr>
              <td style="border-bottom: 1px solid; border-right: 1px solid #000000; vertical-align: top; width: 10%;">&#160;</td>
              <td colspan="3" style="vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0);">
                <div style="text-align: justify;">3,398,248(1)(2)</div>
              </td>
            </tr>
            <tr>
              <td style="border-left: 1px solid #000000; border-right: 1px solid #000000; vertical-align: top; width: 10%;">
                <div>&#160; 11.</div>
              </td>
              <td colspan="4" style="vertical-align: top; border-right: 1px solid rgb(0, 0, 0);">
                <div style="text-align: justify;">Aggregate Amount Beneficially Owned by Each Reporting Person</div>
              </td>
            </tr>
            <tr>
              <td style="border-bottom: 1px solid; border-left: 1px solid #000000; border-right: 1px solid #000000; vertical-align: top; width: 10%;">&#160;</td>
              <td colspan="4" style="vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0);">
                <div style="text-align: justify;">3,398,248(1)</div>
              </td>
            </tr>
            <tr>
              <td style="border-bottom: 1px solid; border-left: 1px solid #000000; border-right: 1px solid #000000; vertical-align: top; width: 10%;">
                <div>&#160; 12.</div>
              </td>
              <td colspan="3" style="vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0);">
                <div style="text-align: justify;">Check if the Aggregate Amount in Row&#160;(11) Excludes Certain Shares</div>
              </td>
              <td style="width: 9.28%; vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0);">
                <div style="text-align: justify;">&#9744;</div>
              </td>
            </tr>
            <tr>
              <td style="border-left: 1px solid #000000; border-right: 1px solid #000000; vertical-align: top; width: 10%;">
                <div>&#160; 13.</div>
              </td>
              <td colspan="4" style="vertical-align: top; border-right: 1px solid rgb(0, 0, 0);">
                <div style="text-align: justify;">Percent of Class&#160;Represented by Amount in Row&#160;(11)</div>
              </td>
            </tr>
            <tr>
              <td style="border-bottom: 1px solid; border-left: 1px solid #000000; border-right: 1px solid #000000; vertical-align: top; width: 10%;">&#160;</td>
              <td colspan="4" style="vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0);">
                <div style="text-align: justify;">8.4%(3)</div>
              </td>
            </tr>
            <tr>
              <td style="border-left: 1px solid #000000; border-right: 1px solid #000000; vertical-align: top; width: 10%;">
                <div>&#160; 14.</div>
              </td>
              <td colspan="4" style="vertical-align: top; border-right: 1px solid rgb(0, 0, 0);">
                <div style="text-align: justify;">Type of Reporting Person</div>
              </td>
            </tr>
            <tr>
              <td style="border-bottom: 1px solid; border-left: 1px solid #000000; border-right: 1px solid #000000; vertical-align: top; width: 10%;">&#160;</td>
              <td colspan="4" style="vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0); border-right: 1px solid rgb(0, 0, 0);">
                <div style="text-align: justify;">OO</div>
              </td>
            </tr>

        </table>
      </div>
      <div style="text-align: justify; text-indent: -18pt; margin-left: 18pt; margin-bottom: 12pt; font-family: 'Times New Roman',Times,serif;">(1) The number of shares of the Issuer reported is based on the Issuer&#8217;s Registration Statement on Form S-4
        filed with the SEC on October 14, 2022, as amended by the Prospectus Supplement filed with the SEC on February 16, 2023, giving effect, in connection with the Merger, to the final exchange ratio of 37.9881 provided by the Issuer and the 1-for-20
        reverse stock split effective at 5:01 p.m. Eastern Time on March 7, 2023, as reported on the Issuer&#8217;s Current Report on Form 8-K filed with the SEC on March 8, 2023.&#160; The number of shares has been amended in this Amendment No. 1 to Schedule 13D to
        reflect the final exchange ratio, which was not known when the Schedule 13D was originally filed. For the avoidance of doubt, no disposition of shares of the Issuer have been made by the reporting person, and this Amendment No. 1 to Schedule 13D is
        being filed solely to reflect such final exchange ratio.<br>
      </div>
      <div style="text-align: justify; text-indent: -18pt; margin-left: 18pt; margin-bottom: 12pt; font-family: 'Times New Roman',Times,serif;">(2)&#160; HealthCap VII GP S.A., a corporation organized under the laws of Switzerland, is the sole general partner
        of HealthCap VII, L.P. and has voting and investment control over the shares. HealthCap VII GP S.A. disclaims beneficial ownership of all shares held by HealthCap VII L.P., except to the extent of their pecuniary interest therein.</div>
      <div style="text-align: justify; text-indent: -18pt; margin-left: 18pt; margin-bottom: 12pt;"> <br>
      </div>
      <div id="DSPFPageBreakArea" style="clear: both; margin-top: 10pt; margin-bottom: 10pt;">
        <div id="DSPFPageBreak" style="page-break-after: always;">
          <hr noshade="noshade" style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;"></div>
      </div>
      <div style="text-align: right; text-indent: -18pt; margin-left: 18pt; margin-bottom: 12pt; font-family: 'Times New Roman',Times,serif;"> Page 4 of 6<br>
      </div>
      <div style="text-align: justify; text-indent: -18pt; margin-left: 18pt; margin-bottom: 12pt; font-family: 'Times New Roman',Times,serif;">(3) As more fully described in Item 5 of this Amendment No. 1 to Schedule 13D, based on 40,254,666 shares of
        Common Stock outstanding as of March 19, 2023, the Reporting Person may be deemed to have beneficial ownership of 3,398,248 shares of Common Stock, which is equal to approximately 8.4% of the voting power of issued and outstanding Common Stock as
        of March 19, 2023.</div>
      <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" id="DSPFPageBreakArea">
        <div style="page-break-after:always;" id="DSPFPageBreak">
          <hr noshade="noshade" style="margin: 4px 0px; width: 100%; border-width: 0; height: 2px; color: #000000; background-color: #000000; clear: both;"></div>
      </div>
      &#160; <br>
      <div style="text-align: right; margin-bottom: 12pt; font-family: 'Times New Roman',Times,serif; font-size: 12pt;"><font style="font-size: 10pt;">Page 5 of 6<br>
        </font></div>
      <br>
    </div>
    <div><font style="font-family: 'Times New Roman',Times,serif; font-weight: bold;">Item&#160;5.&#160;&#160; Interest in Securities of the Issuer.</font>
      <div style="text-align: justify; margin-bottom: 12pt; font-family: 'Times New Roman',Times,serif;"> <br>
      </div>
      <div style="text-align: justify; margin-bottom: 12pt; font-family: 'Times New Roman',Times,serif;"> Item 5 is hereby amended and supplemented as follows:<br>
      </div>
      <div style="text-align: justify; margin-bottom: 12pt; font-family: 'Times New Roman',Times,serif;">(a)-(b) The information set forth in rows 7 through 13 of the cover pages to this Amendment No. 1 to Schedule 13D is incorporated by reference. The
        percentage set forth in row 13 is based on 40,254,666 shares of Common Stock outstanding as of March 19, 2023, as provided by the Issuer.</div>
      <div style="text-align: justify; margin-bottom: 12pt; font-family: 'Times New Roman',Times,serif;">The Fund directly holds 3,398,248 shares of Common Stock. As the sole general partner of the Fund, the General Partner may be deemed to beneficially
        own the shares held by the Fund. Fabrice Bernhard serves as an executive officer of the General Partner, and each of Dag Richter, Daniel Schafer, and Frans Wuite (together with Mr. Bernhard, the &#8220;<font style="font-weight: bold;">Managers</font>&#8221;)
        serves as a director of the General Partner.</div>
      <br>
      <div style="text-align: justify; margin-bottom: 12pt; font-size: 12pt;"> <font style="font-size: 10pt;"><br>
        </font></div>
      <div id="DSPFPageBreakArea" style="clear: both; margin-top: 10pt; margin-bottom: 10pt;">
        <div id="DSPFPageBreak" style="page-break-after: always;">
          <hr noshade="noshade" style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;"></div>
      </div>
      <div style="text-align: right; margin-bottom: 12pt; font-family: 'Times New Roman',Times,serif; font-size: 12pt;">&#160; <font style="font-size: 10pt;"><br>
        </font></div>
      <br>
      <div style="margin-bottom: 12pt;"><br>
      </div>
      <div style="text-align: right;">Page 6 of 6<br>
      </div>
      <div style="text-align: center; margin-bottom: 12pt; font-family: 'Times New Roman',Times,serif; font-weight: bold;">SIGNATURES</div>
      <div style="text-align: justify; text-indent: 36pt; margin-bottom: 12pt; font-family: 'Times New Roman',Times,serif;">After reasonable inquiry and to the best of its knowledge and belief,&#160;the undersigned hereby certify that the information set forth
        in this statement is true, complete and correct.</div>
      <div style="text-align: justify; margin-bottom: 12pt; font-family: 'Times New Roman',Times,serif;">Date: March 22, 2023</div>
      <div style="text-align: justify; margin-left: 252pt; font-family: 'Times New Roman',Times,serif;">HEALTHCAP VII, L.P.</div>
      <div><br>
      </div>
      <div style="text-align: justify; margin-left: 252pt; font-family: 'Times New Roman',Times,serif;">By its general partner HealthCap VII GP S.A.</div>
      <div><br>
      </div>
      <div style="margin-left: 252pt;"><font style="font-family: 'Times New Roman',Times,serif;">By: <u>/s/ Dag Richter &#160; &#160; &#160; &#160; &#160; &#160; &#160; &#160; &#160; &#160; &#160; &#160;</u><u>&#160; </u></font></div>
      <div style="text-align: justify; margin-left: 252pt; font-family: 'Times New Roman',Times,serif;">Name: Dag Richter</div>
      <div style="text-align: justify; margin-left: 252pt; font-family: 'Times New Roman',Times,serif;">Title:&#160;&#160; Director</div>
      <div><br>
      </div>
      <div style="margin-left: 252pt;"><font style="font-family: 'Times New Roman',Times,serif;">By: <u>/s/ Fabrice Bernhard &#160; &#160; &#160; &#160; &#160; &#160; &#160; &#160;</u><u>&#160; </u></font></div>
      <div style="text-align: justify; margin-left: 252pt; font-family: 'Times New Roman',Times,serif;">Name: Fabrice Bernhard</div>
      <div style="text-align: justify; margin-left: 252pt; font-family: 'Times New Roman',Times,serif;">Title:&#160;&#160; General Manager</div>
      <div><br>
      </div>
      <div><br>
      </div>
      <div style="text-align: justify; margin-left: 252pt; font-family: 'Times New Roman',Times,serif;">HEALTHCAP VII GP S.A.</div>
      <div><br>
      </div>
      <div style="margin-left: 252pt;"><font style="font-family: 'Times New Roman',Times,serif;">By: <u>/s/ Dag Richter &#160; &#160; &#160; &#160; &#160; &#160; &#160; &#160; &#160; &#160; &#160; &#160; &#160;&#160;</u><u> </u></font></div>
      <div style="text-align: justify; margin-left: 252pt; font-family: 'Times New Roman',Times,serif;">Name: Dag Richter</div>
      <div style="text-align: justify; margin-left: 252pt; font-family: 'Times New Roman',Times,serif;">Title:&#160;&#160; Director</div>
      <div><br>
      </div>
      <div style="margin-left: 252pt;"><font style="font-family: 'Times New Roman',Times,serif;">By: <u>/s/ </u><u>Fabrice Bernhard &#160; &#160;&#160; &#160; &#160; &#160; &#160; &#160; &#160; &#160; &#160;</u><u> </u></font></div>
      <div style="text-align: justify; margin-left: 252pt; font-family: 'Times New Roman',Times,serif;">Name: Fabrice Bernhard</div>
      <div style="text-align: justify; margin-left: 252pt; font-family: 'Times New Roman',Times,serif;">Title:&#160;&#160; General Manager</div>
      <div><br>
      </div>
      <div style="margin-bottom: 12pt;">
        <hr align="center" style="border: none; border-bottom: 4px solid black; border-top: 1px solid black; height: 10px; color: #ffffff; background-color: #ffffff; text-align: center; margin-left: auto; margin-right: auto;"> </div>
      <div style="text-align: right; margin-left: 216pt; font-family: 'Times New Roman',Times,serif;"><br>
        <font style="font-weight: bold;"></font></div>
      <div>
        <div><br>
        </div>
      </div>
      <br>
    </div>
  </div>
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