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Related-Party Transactions (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2024
Sep. 30, 2023
Sep. 30, 2024
Sep. 30, 2023
Related-Party Transactions        
Research and development $ 11,326 $ 19,551 $ 44,095 $ 54,710
Penn        
Related-Party Transactions        
Research and development   $ 300   $ 600