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Moderna Collaboration and License Agreement - Narrative (Details)
$ in Thousands
 1 Months Ended 3 Months Ended 12 Months Ended
Jan. 31, 2025
USD ($)
Sep. 30, 2024
item
Jun. 30, 2024
USD ($)
Jan. 31, 2022
USD ($)
product
item
Mar. 31, 2025
USD ($)
item
Mar. 31, 2024
USD ($)
Dec. 31, 2024
USD ($)
item
Dec. 31, 2023
USD ($)
Feb. 28, 2025
item
Dec. 31, 2022
USD ($)
Moderna Collaboration and License Agreement                    
Collaboration revenues         $ 3,700 $ 3,400 $ 19,600 $ 14,900    
Deferred revenue liability         41,250 46,189 44,979 46,413   $ 47,459
Collaboration revenues         3,729 $ 3,397 19,632 $ 14,919    
Option Right Collaboration Revenues                    
Moderna Collaboration and License Agreement                    
Collaboration revenues             3,800      
Milestones                    
Moderna Collaboration and License Agreement                    
Collaboration revenues             2,000      
Moderna                    
Moderna Collaboration and License Agreement                    
Collaboration receivable             $ 2,900      
Moderna | Subsequent Event                    
Moderna Collaboration and License Agreement                    
Proceeds from collection of collaboration receivable $ 2,900                  
Collaboration and License Agreement                    
Moderna Collaboration and License Agreement                    
Number of potential research target designations | item             12      
Collaboration and License Agreement | Research and Development Services                    
Moderna Collaboration and License Agreement                    
Variable consideration             $ 73,900      
Term of contract (in years)             5 years      
Noncurrent portion of deferred revenue         41,300   $ 41,300      
Collaboration and License Agreement | Moderna                    
Moderna Collaboration and License Agreement                    
Maximum of research targets | item       12            
Number of nominated autoimmune target | item   2                
Number of oncology research targets | item                 12  
Collaboration and License Agreement | Moderna | Subsequent Event                    
Moderna Collaboration and License Agreement                    
Number of oncology research targets | item                 12  
Collaboration and License Agreement | Moderna | Research and Development Services                    
Moderna Collaboration and License Agreement                    
Upfront non-refundable payment received       $ 45,000 $ 45,000   45,000      
Number of potential products to develop and commercialize | product       12            
Minimum commitment to reimburse research and development costs       $ 10,000            
Period of reimbursement of research and development costs (in years)       3 years            
Number of performance obligations | item         2          
Collaboration and License Agreement | Moderna | Minimum | Research and Development Services                    
Moderna Collaboration and License Agreement                    
Amount receivable per product       $ 247,000            
Collaboration and License Agreement | Moderna | Maximum | Research and Development Services                    
Moderna Collaboration and License Agreement                    
Amount receivable per product       $ 253,000            
Moderna License Agreement | Research and Development Services                    
Moderna Collaboration and License Agreement                    
Collaboration revenues         $ 42,400          
Collaboration revenues             38,700      
Moderna License Agreement | Option Right Collaboration Revenues                    
Moderna Collaboration and License Agreement                    
Collaboration revenues         $ 3,800          
Moderna License Agreement | Moderna                    
Moderna Collaboration and License Agreement                    
Milestone payment     $ 2,000              
Collaboration revenues     $ 2,000              
Deferred revenue liability             45,000      
Decrease in contract with customer, liability             $ 3,800