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Moderna Collaboration and License Agreement - Narrative (Details)
$ in Thousands
 1 Months Ended 3 Months Ended 6 Months Ended 12 Months Ended 42 Months Ended
Jan. 31, 2025
USD ($)
Sep. 30, 2024
item
Jun. 30, 2024
USD ($)
Jan. 31, 2022
USD ($)
item
product
Jun. 30, 2025
USD ($)
Jun. 30, 2024
USD ($)
Jun. 30, 2025
USD ($)
item
Jun. 30, 2024
USD ($)
Dec. 31, 2024
USD ($)
item
Dec. 31, 2023
USD ($)
Jun. 30, 2025
USD ($)
Feb. 28, 2025
item
Dec. 31, 2022
USD ($)
Moderna Collaboration and License Agreement                          
Collaboration revenues             $ 3,700 $ 12,600 $ 19,600 $ 14,900      
Deferred revenue liability     $ 41,909   $ 41,250 $ 41,909 41,250 41,909 44,979 46,413 $ 41,250   $ 47,459
Collaboration revenues         0 9,197 3,729 12,594 19,632 $ 14,919      
Option Right Collaboration Revenues                          
Moderna Collaboration and License Agreement                          
Collaboration revenues                 3,800        
Milestones                          
Moderna Collaboration and License Agreement                          
Collaboration revenues                 2,000        
Moderna                          
Moderna Collaboration and License Agreement                          
Collaboration receivable                 $ 2,900        
Moderna | Subsequent Event                          
Moderna Collaboration and License Agreement                          
Proceeds from collection of collaboration receivable $ 2,900                        
Collaboration and License Agreement                          
Moderna Collaboration and License Agreement                          
Number of potential research target designations | item                 12        
Collaboration and License Agreement | Research and Development Services                          
Moderna Collaboration and License Agreement                          
Variable consideration                 $ 73,900        
Term of contract (in years)                 5 years        
Noncurrent portion of deferred revenue         $ 41,300   41,300   $ 41,300   41,300    
Collaboration and License Agreement | Moderna                          
Moderna Collaboration and License Agreement                          
Maximum of research targets | item       12                  
Number of nominated autoimmune target | item   2                      
Number of oncology research targets | item                       12  
Collaboration and License Agreement | Moderna | Subsequent Event                          
Moderna Collaboration and License Agreement                          
Number of oncology research targets | item                       12  
Collaboration and License Agreement | Moderna | Research and Development Services                          
Moderna Collaboration and License Agreement                          
Upfront non-refundable payment received       $ 45,000     $ 45,000   45,000        
Number of potential products to develop and commercialize | product       12                  
Minimum commitment to reimburse research and development costs       $ 10,000                  
Period of reimbursement of research and development costs (in years)       3 years                  
Number of performance obligations | item             2            
Collaboration and License Agreement | Moderna | Minimum | Research and Development Services                          
Moderna Collaboration and License Agreement                          
Amount receivable per product       $ 247,000                  
Collaboration and License Agreement | Moderna | Maximum | Research and Development Services                          
Moderna Collaboration and License Agreement                          
Amount receivable per product       $ 253,000                  
Moderna License Agreement | Research and Development Services                          
Moderna Collaboration and License Agreement                          
Collaboration revenues                 38,700   42,400    
Moderna License Agreement | Option Right Collaboration Revenues                          
Moderna Collaboration and License Agreement                          
Collaboration revenues                     $ 3,800    
Moderna License Agreement | Moderna                          
Moderna Collaboration and License Agreement                          
Milestone payment     2,000     $ 2,000   $ 2,000          
Collaboration revenues     $ 2,000                    
Deferred revenue liability                 45,000        
Decrease in contract with customer, liability                 $ 3,800