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Related Parties (Details) $ / shares in Units, $ in Thousands |  | 12 Months Ended
--- | --- | ---
Nov. 04, 2015 USD ($) | Dec. 31, 2016 USD ($) shares $ / shares
Senior Secured 2.25% Convertible Debentures [Member] |  |
Related Party Transaction [Line Items] |  |
Aggregate principal amount of debt |  | $ 32,500
Interest rate |  | 2.25%
Number of shares debt convertible (in shares) | shares |  | 43,333,334
Initial conversion price (in dollars per share) | $ / shares |  | $ 0.75
Maturity period |  | 5 years
Maturity date |  | Jun. 30, 2021
Sabby Management LLC and Broadfin LLC [Member] | Senior Secured 2.25% Convertible Debentures [Member] |  |
Related Party Transaction [Line Items] |  |
Aggregate principal amount of debt |  | $ 32,500
Interest rate |  | 2.25%
Number of shares underlying warrants (in shares) | shares |  | 3,000,000
Exercise price of warrants (in dollars per share) | $ / shares |  | $ 0.75
Number of shares debt convertible (in shares) | shares |  | 43,333,334
Initial conversion price (in dollars per share) | $ / shares |  | $ 0.75
Maturity period |  | 5 years
Maturity date |  | Jun. 30, 2021
Percentage of liquidated damages payable |  | 2.00%
Percentage of aggregate liquidated damages payable |  | 12.00%
Interest rate payable on liquidated damages |  | 12.00%
Percentage of issued and outstanding common stock payable upon conversion |  | 9.99%
Sabby Management LLC and Broadfin LLC [Member] | Senior Secured Notes Payable [Member] |  |
Related Party Transaction [Line Items] |  |
Aggregate principal amount of debt |  | $ 10,000
Number of days for stockholders approval considered for maturity date |  | 30 days
Interest rate |  | 9.00%
Two Board Directors [Member] |  |
Related Party Transaction [Line Items] |  |
Up-front fee paid | $ 40,000 |
Monthly retainer fee |  | $ 10,000

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