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Document and Entity Information - USD ($)
 12 Months Ended
Dec. 31, 2022
Mar. 17, 2023
Jun. 30, 2022
Document and Entity Information      
Document Type 10-K    
Document Annual Report true    
Document Period End Date Dec. 31, 2022    
Document Transition Report false    
Entity File Number 001-37939    
Entity Registrant Name MARKER THERAPEUTICS, INC.    
Entity Incorporation, State or Country Code DE    
Entity Tax Identification Number 45-4497941    
Entity Address, Address Line One 4551 Kennedy Commerce Drive    
Entity Address, City or Town Houston    
Entity Address, State or Province TX    
Entity Address, Postal Zip Code 77032    
City Area Code 713    
Local Phone Number 400-6400    
Title of 12(b) Security Common Stock, par value $0.001 per share    
Trading Symbol MRKR    
Security Exchange Name NASDAQ    
Entity Current Reporting Status Yes    
Entity Interactive Data Current Yes    
Entity Filer Category Non-accelerated Filer    
Entity Small Business true    
Entity Emerging Growth Company false    
ICFR Auditor Attestation Flag false    
Entity Shell Company false    
Entity Common Stock, Shares Outstanding   8,798,829  
Entity Central Index Key 0001094038    
Current Fiscal Year End Date --12-31    
Document Fiscal Year Focus 2022    
Document Fiscal Period Focus FY    
Amendment Flag false    
Auditor Name Marcum LLP    
Auditor Firm ID 688    
Auditor Location Houston, TX    
Entity Well-known Seasoned Issuer No    
Entity Public Float     $ 22,800,000
Entity Voluntary Filers No