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STOCK OPTION PLANS (Tables)

12 Months Ended

Dec. 31, 2022

STOCK OPTION PLANS

Summary of the company's stock option activity

​

​	​	​	​	​	​	​	​	​	​	​
​		​		​	​	​	​	​		Weighted Average
​	​	​	​	​	​	​	​	​	​	Remaining
​	​	​	​	Weighted Average		​	​	​	​	Contractual
​		Number of Shares		Exercise Price			Total Intrinsic Value			Life (in years)
Outstanding as of January 1, 2021		600,181	​	$	62.18	​	$	—	​	8.3
Granted		191,500	​	​	28.97	​	​	—	​	8.9
Exercised	​	(146)	​	​	21.20	​	​	—	​	—
Canceled/Expired		(22,912)	​	​	35.92	​	​	—	​	—
Outstanding as of December 31, 2021		768,623	​	​	54.69	​	​	—	​	7.7
Granted		260,000	​		4.68	​		—	​	7.8
Canceled/Expired		(142,450)	​		36.78	​		—	​	—
Outstanding as of December 31, 2022		886,173	​	$	42.90	​	$	—	​	7.3
Options vested and exercisable		560,929	​	$	59.39	​	$	—	​	6.6

​

Schedule or description of weighted average discount rate

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​	​	​	​	​	​	​	​
​	​	For the Years Ended					​
​	​	December 31,					​
​		2022			2021		​
Exercise price	​	$	4.70	​	$	29.00	​
Expected term (years)	​		5.9	​		6.0	​
Expected stock price volatility	​		85	%		94	%
Risk-free rate of interest	​		2	%		1	%
Expected dividend rate	​		0	%		0	%

​

Schedule of stock-based compensation expenses

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​	​	​	​	​	​	​
​		For the Years Ended
​	​	December 31,
​		2022			2021
Stock Compensation expenses:		​			​
Research and development	​	$	2,691,000	​	$	2,856,000
General and administrative	​		2,653,000	​		3,108,000
Total stock compensation expenses	​	$	5,344,000	​	$	5,964,000

​

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Tabular disclosure of stock based compensation expenses recorded.

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Tabular disclosure of activity for award under share-based payment arrangement. Includes, but is not limited to, outstanding award at beginning and end of year, granted, exercised, forfeited, and weighted-average grant date fair value.

+ References

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-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
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Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions.

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-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
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