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FINANCIAL CONDITION, GOING CONCERN AND MANAGEMENT PLANS (Details) - USD ($)						1 Months Ended		3 Months Ended	12 Months Ended
	Mar. 13, 2023	Dec. 12, 2022	Sep. 13, 2022	Apr. 21, 2021	Mar. 16, 2021	Jan. 31, 2023	Aug. 31, 2021	Dec. 31, 2021	Dec. 31, 2022	Dec. 31, 2021
FINANCIAL CONDITION, GOING CONCERN AND MANAGEMENT PLANS
Cash and cash equivalents									$ 11,800,000
Number of shares issued					3,228,286
Proceeds from issuance of common stock, net					$ 52,600,000				202,130	$ 52,552,758
Issuance of common shares for cash									202,130	52,552,758
Amount of notice received							$ 13,100,000
Funds received from CPRIT grant							4,800,000	$ 2,400,000
Revenue from CPRIT									3,400,000
Deferred revenue								$ 1,146,186	0	$ 1,146,186
Grant income received			$ 2,000,000.0
Grant revenue									100,000
Grant income receivable									$ 100,000
Funds received from CPRIT grant						$ 2,400,000
Common Stock
FINANCIAL CONDITION, GOING CONCERN AND MANAGEMENT PLANS
Number of shares issued									60,651	3,228,286
Issuance of common shares for cash									$ 61	$ 3,228
Lincoln Park
FINANCIAL CONDITION, GOING CONCERN AND MANAGEMENT PLANS
Commitment fee						$ 500,000
Lincoln Park | Common Stock
FINANCIAL CONDITION, GOING CONCERN AND MANAGEMENT PLANS
Stock issued during period other		$ 25,000,000
Stock issued during period other (in shares)						180,410
Subsequent event
FINANCIAL CONDITION, GOING CONCERN AND MANAGEMENT PLANS
Funds received from CPRIT grant	$ 100,000					$ 100,000
ATM Agreement | Common Stock
FINANCIAL CONDITION, GOING CONCERN AND MANAGEMENT PLANS
Number of shares issued									60,651
Stock issued during period for services									$ 200,000
ATM Agreement | Sales Agents
FINANCIAL CONDITION, GOING CONCERN AND MANAGEMENT PLANS
Aggregate offering price							$ 75,000,000.0
Commission rate							3.00%
Binding Services Agreement
FINANCIAL CONDITION, GOING CONCERN AND MANAGEMENT PLANS
Issuance of common shares for cash				$ 8,000,000.0
Binding Services Agreement | Wilson Wolf Manufacturing Corporation
FINANCIAL CONDITION, GOING CONCERN AND MANAGEMENT PLANS
Revenue recognized									5,500,000
Deferred revenue									$ 2,500,000

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