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RELATED PARTY TRANSACTIONS (Details) - USD ($)
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
RELATED PARTY TRANSACTIONS    
Total Research and development $ 1,508,000 $ 3,437,000
Baylor College of Medicine    
RELATED PARTY TRANSACTIONS    
Total Research and development 1,142,000 2,851,000
Bio-Techne Corporation    
RELATED PARTY TRANSACTIONS    
Total Research and development 101,000 306,000
Wilson Wolf Manufacturing Corporation    
RELATED PARTY TRANSACTIONS    
Total Research and development $ 265,000 $ 280,000