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Document and Entity Information - USD ($)
 12 Months Ended
Dec. 31, 2025
Mar. 16, 2026
Jun. 30, 2025
Document and Entity Information      
Document Type 10-K    
Document Annual Report true    
Document Period End Date Dec. 31, 2025    
Document Transition Report false    
Entity File Number 001-37939    
Entity Registrant Name MARKER THERAPEUTICS, INC.    
Entity Incorporation, State or Country Code DE    
Entity Tax Identification Number 45-4497941    
Entity Address, Address Line One 2450 Holcombe Blvd, TMC Partners Office 1.311    
Entity Address, City or Town Houston    
Entity Address, State or Province TX    
Entity Address, Postal Zip Code 77021    
City Area Code 713    
Local Phone Number 400-6400    
Title of 12(b) Security Common Stock, par value $0.001 per share    
Trading Symbol MRKR    
Security Exchange Name NASDAQ    
Entity Well-known Seasoned Issuer No    
Entity Voluntary Filers No    
Entity Current Reporting Status Yes    
Entity Interactive Data Current Yes    
Entity Filer Category Non-accelerated Filer    
Entity Small Business true    
Entity Emerging Growth Company false    
ICFR Auditor Attestation Flag false    
Document Financial Statement Error Correction [Flag] false    
Entity Shell Company false    
Entity Public Float     $ 17,312,000
Entity Common Stock, Shares Outstanding   16,673,127  
Documents Incorporated by Reference [Text Block] Portions of the registrant’s proxy statement relating to registrant’s 2025 Annual Meeting of Stockholders (the “Proxy Statement”) to be filed with the Securities and Exchange Commission pursuant to Regulation 14A, not later than 120 days after the close of the registrant’s fiscal year, are incorporated by reference in Part III of this Annual Report on Form 10-K. Except with respect to information specifically incorporated by reference in this Annual Report on Form 10-K, the Proxy Statement is not deemed to be filed as part of this Annual Report on Form 10-K    
Entity Central Index Key 0001094038    
Current Fiscal Year End Date --12-31    
Document Fiscal Year Focus 2025    
Document Fiscal Period Focus FY    
Amendment Flag false    
Auditor Name Marcum LLP    
Auditor Firm ID 688    
Auditor Location Houston, TX