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CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY - USD ($)
Common Stock
Additional Paid-in Capital
Accumulated Deficit
Total
Beginning Balance at Dec. 31, 2023 $ 8,891 $ 450,329,515 $ (436,285,863) $ 14,052,543
Beginning Balance (in shares) at Dec. 31, 2023 8,891,420      
Shares purchased pursuant to ATM agreement $ 8 36,894   36,902
Shares purchased pursuant to ATM agreement (in shares) 8,178      
Issuance of common stock from exercise of stock options $ 25 62,134   $ 62,159
Issuance of common stock from exercise of stock options (in shares) 25,602     25,602
Issuance of common stock, prefunded warrants and warrants for cash, net of offering costs $ 1,784 14,890,469   $ 14,892,253
Issuance of common stock, prefunded warrants and warrants for cash, net of offering costs (in shares) 1,783,805      
Stock-based compensation   245,864   245,864
Net loss     (10,731,315) (10,731,315)
Ending Balance at Dec. 31, 2024 $ 10,708 465,564,876 (447,017,178) 18,558,406
Ending Balance (in shares) at Dec. 31, 2024 10,709,005      
Shares purchased pursuant to ATM agreement $ 5,359 9,858,524   9,863,883
Shares purchased pursuant to ATM agreement (in shares) 5,358,292      
Issuance of common stock from exercise of prefunded warrants $ 605     605
Issuance of common stock from exercise of prefunded warrants (in shares) 605,830      
Stock-based compensation   537,540   537,540
Net loss     (12,163,620) (12,163,620)
Ending Balance at Dec. 31, 2025 $ 16,672 $ 475,960,940 $ (459,180,798) $ 16,796,814
Ending Balance (in shares) at Dec. 31, 2025 16,673,127