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STATEMENTS OF CHANGES IN SHAREHOLDERS' EQUITY - USD ($)
$ in Thousands
Ordinary Share
Additional paid-in capital [Member]
Accumulated deficit [Member]
Total
Balance at Dec. 31, 2017 $ 84 $ 134,843 $ (131,220) $ 3,707
Balance, shares at Dec. 31, 2017 1,200,146      
Cumulative effect to accumulated deficit from adoption of a new accounting standard (23) (23)
Share-based compensation to employees and non-employees 2,766 2,766
Issuance of ordinary shares upon exercise of options to purchase ordinary shares and RSUs by employees and non-employees [1]
Issuance of ordinary shares upon exercise of options to purchase ordinary shares and RSUs by employees and non-employees, shares 17,181      
Issuance of ordinary shares in investing agreement, net of issuance expenses in an amount of $830 [2] $ 12 4,283 4,295
Issuance of ordinary shares in investing agreement, net of issuance expenses in an amount of $830, shares [2] 164,715      
Issuance of ordinary shares in at-the-market offering, net of issuance expenses in the amount of $236 [2] $ 4 1,113 1,117
Issuance of ordinary shares in at-the-market offering, net of issuance expenses in the amount of $236, shares [2] 49,882      
Issuance of ordinary shares, warrants and pre-funded warrants in follow-on public offering, net of issuance expenses in an amount of $1,505 [2] $ 49 11,528 11,577
Issuance of ordinary shares, warrants and pre-funded warrants in follow-on public offering, net of issuance expenses in an amount of $1,505, shares [2] 728,019      
Modification of warrants to purchase ordinary shares [3] 18 18
Exercise of pre-funded warrants [2] $ 44 119 163
Exercise of pre-funded warrants, shares [2] 653,144      
Issuance of ordinary shares in a "best effort" offering, net of issuance expenses in the amount of $686      
Net loss (21,675) (21,675)
Balance at Dec. 31, 2018 $ 193 154,670 (152,918) 1,945
Balance, shares at Dec. 31, 2018 2,813,087      
Share-based compensation to employees and non-employees 1,108 1,108
Issuance of ordinary shares upon exercise of options to purchase ordinary shares and RSUs by employees and non-employees $ 2 2
Issuance of ordinary shares upon exercise of options to purchase ordinary shares and RSUs by employees and non-employees, shares 47,473      
Issuance of ordinary shares in a "best effort" offering, net of issuance expenses in the amount of $686 [2] $ 52 3,632 3,684
Issuance of ordinary shares in a "best effort" offering, net of issuance expenses in the amount of $686, shares [2] 760,000      
Exercise of pre-funded warrants and warrants [2] $ 40 1,461 1,501
Exercise of pre-funded warrants and warrants, shares [2] 584,087      
Issuance of ordinary shares in a "Registered Direct" offering, net of issuance expenses in the amount of $ 1,125 [2] $ 115 8,010 8,125
Issuance of ordinary shares in a "Registered Direct" offering, net of issuance expenses in the amount of $ 1,125, shares [2] 1,650,248      
Issuance of ordinary shares in a "Warrant exercise" agreement, net of issuance expenses in the amount of $ 1,019 [2] $ 102 9,864 9,966
Issuance of ordinary shares in a "Warrant exercise" agreement, net of issuance expenses in the amount of $ 1,019,shares 1,464,665      
Net loss (15,551) (15,551)
Balance at Dec. 31, 2019 $ 504 178,745 (168,469) 10,780
Balance, shares at Dec. 31, 2019 7,319,560      
Share-based compensation to employees and non-employees 749 749
Issuance of ordinary shares upon exercise of options to purchase ordinary shares and RSUs by employees and non-employees $ 3 (3)
Issuance of ordinary shares upon exercise of options to purchase ordinary shares and RSUs by employees and non-employees, shares 63,111      
Issuance of ordinary shares in a "Best Efforts" offering, net of issuance expenses in the amount of $ 1,056 [2] $ 290 3,720 4,010
Issuance of ordinary shares in a "Best Efforts" offering, net of issuance expenses in the amount of $ 1,056, shares [2] 4,053,172      
Issuance of ordinary shares in a "best effort" offering, net of issuance expenses in the amount of $686      
Exercise of pre-funded warrants and warrants [2] $ 244 3,979 4,223
Exercise of pre-funded warrants and warrants, shares [2] 3,378,328      
Issuance of ordinary shares in a "registered direct" offering, net of issuance expenses in the amount of $ 1,019 [2] $ 357 7,624 7,981
Issuance of ordinary shares in a "registered direct" offering, net of issuance expenses in the amount of $ 1,019, shares [2] 4,938,278      
Issuance of ordinary shares in a private placement, net of issuance expenses in the amount of $ 993 [2] $ 429 6,578 7,007
Issuance of ordinary shares in a private placement, net of issuance expenses in the amount of $ 993, shares [2] 5,579,776      
Net loss (12,976) (12,976)
Balance at Dec. 31, 2020 $ 1,827 $ 201,392 $ (181,445) $ 21,774
Balance, shares at Dec. 31, 2020 25,332,225      
[1] Represents an amount lower than $1.
[2] See note 8b.
[3] See note 8f.