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Equity Incentive Plans (Tables)

12 Months Ended

Dec. 31, 2024

Share-based Compensation Arrangement by Share-based Payment Award [Line Items]

Black-Scholes Weighted Average Assumptions

The Black-Scholes weighted average assumptions for all stock option awards granted during 2024 and 2023 were as follows:

		2024								2023
		2021 Plan				Inducement Grants				2021 Plan
Fair Value of Awards		$	0.91				0.94				0.48
Grant Price		$	1.07				1.1				0.59
Expected term (in years)			6.20				6.25				5.63
Risk‑free interest rate			4.04	%			4.10	%			4.09	%
Dividend yield			—	%			—	%			—	%
Expected volatility			109.61	%			109.64	%			105.33	%

Options Outstanding and Vested and Currently Exercisable by Exercise Prices

The options outstanding and vested and currently exercisable by exercise prices as of December 31, 2024 were as follows:

Options outstanding												Options vested and exercisable
								Weighted								Weighted				Weighted
								average				Number of				average				average
Exercise				Outstanding				remaining				options				Exercise				remaining
price				(in shares)				life years				vested				price				life years
$	0.47 - 0.49				1,063,600				8.50				716,950			$	0.49				8.50
	0.50 - 0.80				565,321				9.05				22,867				0.59				8.47
	0.81 - 1.33				564,450				9.40				20,325				0.88				8.42
	1.34 - 1.74				210,846				2.26				85,335				1.67				2.45
	1.75 - 3.14				164,325				7.70				57,225				2.64				7.53
	3.15 - 3.60				237,614				2.49				237,614				3.24				2.49
	3.61 - 13.00				168,063				5.75				168,063				9.68				5.74
					2,974,219				7.65				1,308,379				2.35				6.62

Share-based Compensation Expense

The following table shows the stock-based compensation expense related to vested stock option grants to employees and non-employees awarded under the stock plans and inducement grants by financial statement line item on the accompanying statements of comprehensive loss:

		2024				2023
Research and development		$	179,911				159,816
Sales and marketing			48,379				(948	)
General and administrative			215,857				516,832
Total share-based compensation expense		$	444,147				675,700

2021 Stock Option Plan [Member]

Share-based Compensation Arrangement by Share-based Payment Award [Line Items]

Stock Option Plan Activity

Activity under the stock option plans was as follows:

		Number of options				Weighted average exercise price				Aggregate Intrinsic Value
Outstanding at December 31, 2022			931,550			$	3.97
Granted			1,301,200				0.59
Forfeited			(130,720	)			1.97
Outstanding at December 31, 2023			2,102,030			$	2.00
Granted			1,359,821				1.07
Forfeited			(487,632	)			1.84
Outstanding at December 31, 2024			2,974,219			$	1.60				847,758
Vested and exercisable at December 31, 2024			1,308,379			$	2.35				453,514

Stock options granted under the 2021 Plan for the years ended December 31 2024 and 2023 were as follows:

		2024				2023
Employee			1,286,921				1,211,200
Nonemployee			72,900				90,000
Total			1,359,821				1,301,200

Inducement Grants [Member]

Share-based Compensation Arrangement by Share-based Payment Award [Line Items]

Stock Option Plan Activity

The inducement grants are summarized as follows:

						Weighted				Weighted
						average				average
		Number of				exercise				remaining
		options				price				life years
Outstanding at December 31, 2023			150,000			$	2.42				8.40
Granted			100,000				1.10				9.12
Outstanding at December 31, 2024			250,000			$	1.89				8.07
Vested and exercisable at December 31, 2024			75,000			$	2.42				7.36

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