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Stockholders' Equity - Stock-based compensation expense (Details) - USD ($) $ in Thousands | 12 Months Ended
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Dec. 31, 2019 | Dec. 31, 2018
Share-based Compensation | $ 2,664 | $ 4,960
General and administrative |  |
Share-based Compensation | 1,790 | 3,664
Research and development |  |
Share-based Compensation | $ 874 | $ 1,296

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- Definition Amount of noncash expense for share-based payment arrangement. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=118932676&loc=d3e3602-108585 + Details
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