<SEC-DOCUMENT>0000899243-20-012176.txt : 20200506
<SEC-HEADER>0000899243-20-012176.hdr.sgml : 20200506
<ACCEPTANCE-DATETIME>20200506193444
ACCESSION NUMBER:		0000899243-20-012176
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20200505
FILED AS OF DATE:		20200506
DATE AS OF CHANGE:		20200506

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Polaris Venture Management Co IV LLC
		CENTRAL INDEX KEY:			0001295438
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-39273
		FILM NUMBER:		20854108

	BUSINESS ADDRESS:	
		STREET 1:		ONE MARINA PARK DRIVE
		STREET 2:		10TH FLOOR
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02210
		BUSINESS PHONE:		7812900770

	MAIL ADDRESS:	
		STREET 1:		ONE MARINA PARK DRIVE
		STREET 2:		10TH FLOOR
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02210

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			POLARIS VENTURE PARTNERS ENTREPRENEURS FUND IV LP
		CENTRAL INDEX KEY:			0001170720
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-39273
		FILM NUMBER:		20854109

	BUSINESS ADDRESS:	
		STREET 1:		1000 WINTER STREET
		STREET 2:		SUITE 3350
		CITY:			WALTHAM
		STATE:			MA
		ZIP:			02451-1215
		BUSINESS PHONE:		7812900770

	MAIL ADDRESS:	
		STREET 1:		1000 WINTER STREET
		STREET 2:		SUITE 3350
		CITY:			WALTHAM
		STATE:			MA
		ZIP:			02451

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			POLARIS VENTURE PARTNERS IV LP
		CENTRAL INDEX KEY:			0001157864
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-39273
		FILM NUMBER:		20854110

	BUSINESS ADDRESS:	
		STREET 1:		1000 WINTER STREET
		STREET 2:		SUITE 3350
		CITY:			WALTHAM
		STATE:			MA
		ZIP:			024511215
		BUSINESS PHONE:		7812900770

	MAIL ADDRESS:	
		STREET 1:		1000 WINTER STREET
		STREET 2:		SUITE 3350
		CITY:			WALTHAM
		STATE:			MA
		ZIP:			02451

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Lyra Therapeutics, Inc.
		CENTRAL INDEX KEY:			0001327273
		STANDARD INDUSTRIAL CLASSIFICATION:	SURGICAL & MEDICAL INSTRUMENTS & APPARATUS [3841]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		480 ARSENAL STREET
		CITY:			WATERTOWN
		STATE:			MA
		ZIP:			02472
		BUSINESS PHONE:		617-373-4600

	MAIL ADDRESS:	
		STREET 1:		480 ARSENAL STREET
		CITY:			WATERTOWN
		STATE:			MA
		ZIP:			02472

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	480 Biomedical, Inc.
		DATE OF NAME CHANGE:	20120927

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Arsenal Vascular, Inc.
		DATE OF NAME CHANGE:	20110826

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Arsenal Medical, Inc.
		DATE OF NAME CHANGE:	20090414
</SEC-HEADER>
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    <footnotes>
        <footnote id="F1">Each share of preferred stock was automatically converted into 0.0289998 shares of common stock upon the closing of the Issuer's initial public offering.  The preferred stock had no expiration date.</footnote>
        <footnote id="F2">The reportable securities are owned directly by Polaris Venture Partners Entrepreneurs' Fund IV, L.P. (&quot;PVPE IV&quot;). PVM IV is the general partner of PVPE IV. Each of Flint and McGuire are the managing members of PVM IV and may be deemed to have shared voting and dispositive power over the shares held by PVPE IV. Each of PVM IV, Flint and McGuire disclaims beneficial ownership of these securities and this report shall not be deemed an admission that any one of them is the beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of their respective pecuniary interests therein.</footnote>
        <footnote id="F3">The reportable securities are owned directly by Polaris Venture Partners IV, L.P. (&quot;PVP IV&quot;). Polaris Venture Management Co. IV, L.L.C. (&quot;PVM IV&quot;) is the general partner of PVP IV. Each of Jonathan A. Flint (&quot;Flint&quot;) and Terrance G. McGuire (&quot;McGuire&quot;) are the managing members of PVM IV and may be deemed to have shared voting and dispositive power over the shares held by PVP IV. Each of PVM IV, Flint and McGuire disclaims beneficial ownership of these securities and this report shall not be deemed an admission that any one of them is the beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of their respective pecuniary interests therein.</footnote>
    </footnotes>

    <remarks>Flint and McGuire are also the managing members of Polaris Venture Management Co. V, L.L.C., which is the sole general partner of each of Polaris Venture Partners V, L.P., Polaris Venture Partners Entrepreneurs' Fund V, L.P., Polaris Venture Partners Founders' Fund V, L.P., and Polaris Venture Partners Special Founders' Fund V, L.P. Due to limitations of the EDGAR filing system, this report on Form 4 is one of two reports which are being filed to enable all joint filers to gain access to the EDGAR filing system.</remarks>

    <ownerSignature>
        <signatureName>/s/ Lauren Crockett, Attorney-in-Fact for Polaris Venture Management Co. IV, L.L.C., general partner of Polaris Venture Partners Entrepreneurs' Fund IV, L.P.</signatureName>
        <signatureDate>2020-05-06</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Lauren Crockett, Attorney-in-Fact for Polaris Venture Management Co. IV, L.L.C., general partner of Polaris Venture Partners IV, L.P.</signatureName>
        <signatureDate>2020-05-06</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Lauren Crockett, Attorney-in-Fact for Polaris Venture Management Co. IV, L.L.C</signatureName>
        <signatureDate>2020-05-06</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
