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    ACCESSION NUMBER:		0001193125-20-065213
    CONFORMED SUBMISSION TYPE:	S-1
    PUBLIC DOCUMENT COUNT:		48
    FILED AS OF DATE:		20200306
    DATE AS OF CHANGE:		20200306

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    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Lyra Therapeutics, Inc.
    		CENTRAL INDEX KEY:			0001327273
    		STANDARD INDUSTRIAL CLASSIFICATION:	SURGICAL & MEDICAL INSTRUMENTS & APPARATUS [3841]
    		IRS NUMBER:				000000000
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		S-1
    		SEC ACT:		1933 Act
    		SEC FILE NUMBER:	333-236962
    		FILM NUMBER:		20695733

    	BUSINESS ADDRESS:
    		STREET 1:		480 ARSENAL STREET
    		CITY:			WATERTOWN
    		STATE:			MA
    		ZIP:			02472
    		BUSINESS PHONE:		617-373-4600

    	MAIL ADDRESS:
    		STREET 1:		480 ARSENAL STREET
    		CITY:			WATERTOWN
    		STATE:			MA
    		ZIP:			02472

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	480 Biomedical, Inc.
    		DATE OF NAME CHANGE:	20120927

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	Arsenal Vascular, Inc.
    		DATE OF NAME CHANGE:	20110826

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	Arsenal Medical, Inc.
    		DATE OF NAME CHANGE:	20090414
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